ECOG-ACRIN BY THE NUMBERS

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Announcements

Registration for the Fall 2019 Group Meeting will open by late August. Email announcements will circulate when registration opens.

The CRA Core Committee is offering limited travel assistance to the Fall 2019 Group Meeting More Here

Call for Abstracts: Young investigators interested in presenting your research at the Fall 2019 Group Meeting may submit an abstract now Apply Here

Don’t miss the June 2019 Newsletter 

Like what you’re reading? We want your feedback! Please take a two-minute newsletter Readership Survey

ComboMATCH concept sheets are being accepted until further notice More Here

NEW! Did you know there is a new TMIST newsletter? More Here

Latest News

The results of leukemia trial E1912 are published in The New England Journal of Medicine. Tait Shanafelt, MD (Stanford University) and colleagues report that treatment with the combination of ibrutinib and rituximab is superior to standard treatment for patients 70 years of age or younger, with chronic lymphocytic leukemia (CLL) More Here 

 

The Journal of Clinical Oncology has published the results of the ACRIN 6685 trial. Val J. Lowe, MD (Mayo Clinic) and colleagues report that surgical planning for head and neck cancer benefits from FDG-PET/CT, especially in patients who are clinically node-negative  More Here

 

San Antonio Breast Cancer Symposium honors ECOG-ACRIN vice chair Joseph A. Sparano, MD with its prestigious William L. McGuire Memorial Lecture Award More Here

 

 

TMIST

Amy Curtis, MD (Spartanburg Medical Center): Women are intrigued by the many questions asked in TMIST Conversation with The Cancer Letter

 

 

TAILORx

  • ASCO updates guidelines for early breast cancer based on TAILORx, MINDACT trials News Article

  • TAILORx data guides adjuvant therapy in younger breast cancer patients Press Release

  • The New England Journal of Medicine publishes analysis of a pre-specified secondary analysis that adds new information to the original TAILORx findings NEJM Article

  • “The Precision of Evidence Needed to Practice “Precision Medicine” NEJM Accompanying Editorial

  • Updated ASCO guidelines establish TAILORx-defined cutoffs for determining chemotherapy benefit with the Oncotype DX Breast Recurrence Score® test in node-negative breast cancer Press Release

  • One Year Post-TAILORx: Attitudes Shift and Questions Linger in Breast Cancer Recurrence Testing GenomeWeb (requires free registration) 

  • Using Genomic Profiling to Guide Treatment Decisions for ER-Positive Breast Cancers, by Harold J. Burstein, MD, PhD CancerNetwork

  • New TAILORx Data Provide Treatment Guidance for Women Under 50 With Early Breast Cancer The ASCO Post

NCI-MATCH

  • Arm H finds the combination of dabrafenib and trametinib effective in a heavily pre-treated cohort of 17 distinct tumor types–several rare–with BRAF mutations Press Release

  • Keith Flaherty, MD, ECOG-ACRIN study chair, comments on targeted drugs in an article on basket trials published in Xconomy National

E2810

  • Final results show no benefit from pazopanib in advanced kidney cancer after surgery to remove metastases Press Release

  • ASCO 2019: Randomized, Double-Blind Phase III Study of Pazopanib versus Placebo in Patients with Metastatic Renal Cell Carcinoma who have no Evidence of Disease Following Metastasectomy – Medical Oncologist Perspective UroToday
  • No benefit from pazopanib in advanced kidney cancer after surgery to remove metastases Medical Xpress

E3A06

  • Final results demonstrate that lenalidomide reduces the risk that precancer myeloma will progress to overt multiple myeloma in high-risk individuals Press Release

E1609

  • Low-Dose Ipilimumab Demonstrates Overall Survival Advantage Over High-Dose Interferon-alpha2b in Resected High-Risk Melanoma ASCO Daily News

Group Meeting Highlights

 

Welcome

Welcome to the ECOG-ACRIN Cancer Research Group website, the source of information about the cooperative group that was formed by the merger of the Eastern Cooperative Oncology Group (ECOG) and the American College of Radiology Imaging Network (ACRIN). We are excited to share news of our collaborative effort to design and conduct ground-breaking translational and clinical research.

The merger brought together the strengths and capabilities of two highly respected organizations. Since 1955, ECOG has performed practice-changing multicenter cancer clinical trials, working with more than 6000 physicians, nurses, pharmacists, statisticians, clinical research associates, and cancer research advocates from the United States and around the world. ACRIN, the premier imaging science program in the nation, complements ECOG’s research efforts with its expertise in early detection, imaging diagnosis, comparative-effectiveness research, and cost-effectiveness analysis. Now, as a single entity, we aim to achieve earlier cancer detection, more successful therapeutic intervention, higher rates of prevention, and better patient outcomes.

We look forward to sharing our research and partnering with you, as we reshape the future of patient care.

 

Robert L. Comis, MD
Group Co-Chair


Mitchell D. Schnall, MD, PhD
Group Co-Chair
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