Biomarker Sciences Program

The novel Biomarker Sciences Program exists to support the clinical research of the two other scientific programs in the ECOG-ACRIN Cancer Research Group (ECOG-ACRIN). This program contains three large scientific groups, by specialty: the Developmental Therapeutics Committee, Imaging Committee, and Laboratory Science and Pathology Committee. Together, researchers in this program:

  • Evaluate and integrate cross-cutting biologic science opportunities
  • Attract basic and translational science from member and external organizations
  • Foster translational and correlative science across the Group

The Biomarker Steering Committee, shown below, guides the program and the cross-committee interactions among researchers.

1Summary: The Three Committees
The Imaging Committee is the hub for imaging scientists to engage with the Group. Leaders of early-phase research programs in cancer centers and the National Cancer Institute's (NCI) Specialized Programs of Research Excellence (SPORES) participate in the Developmental Therapeutics Committee to maximize awareness of emerging, cutting-edge therapies. Via the Laboratory Science and Pathology Committee, ECOG-ACRIN engages with experts in somatic genetics, circulating tumor analyses, and immunologic assay development. These committees have made major contributions to the design and implementation of the NCI-MATCH precision medicine cancer trial. The entire program draws heavily on the resources of ECOG-ACRIN's network of Research Cores.

Biomarker Steering Committee



Co-Chair

Represents the program as a deputy chair on the Executive Committee

Co-Chair

Co-Chair

Co-Chair

Keith T. Flaherty, MD

Harvard University, the Dana-Farber/Harvard Cancer Center, and the Massachusetts General Hospital Cancer Center
Biography

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Stanley R. Hamilton, MD

City of Hope
Biography

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David A. Mankoff, MD, PhD

University of Pennsylvania and the Abramson Cancer Center
Biography

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Anthony F. Shields, MD, PhD

Wayne State University and the Barbara Ann Karmanos Cancer Institute
Biography

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ECOG-ACRIN Cancer Research Group