Biomarker Sciences Program

The novel Biomarker Sciences Program exists to support the clinical research of the two other scientific programs in the ECOG-ACRIN Cancer Research Group (ECOG-ACRIN). This program contains three large scientific groups, by specialty: the Developmental Therapeutics Committee, Imaging Committee, and Laboratory Science and Pathology Committee. Together, researchers in this program:

  • Evaluate and integrate cross-cutting biologic science opportunities
  • Attract basic and translational science from member and external organizations
  • Foster translational and correlative science across the Group

The Biomarker Steering Committee, shown below, guides the program and the cross-committee interactions among researchers.

1Summary: The Three Committees
The Imaging Committee is the hub for imaging scientists to engage with the Group. Leaders of early-phase research programs in cancer centers and the National Cancer Institute's (NCI) Specialized Programs of Research Excellence (SPORES) participate in the Developmental Therapeutics Committee to maximize awareness of emerging, cutting-edge therapies. Via the Laboratory Science and Pathology Committee, ECOG-ACRIN engages with experts in somatic genetics, circulating tumor analyses, and immunologic assay development. These committees have made major contributions to the design and implementation of the NCI-MATCH precision medicine cancer trial. The entire program draws heavily on the resources of ECOG-ACRIN's network of Research Cores.

Biomarker Steering Committee



Co-Chair

Represents the program as a deputy chair on the Executive Committee

Co-Chair

Co-Chair

Co-Chair

Keith T. Flaherty, MD

Harvard University, the Dana-Farber/Harvard Cancer Center, and the Massachusetts General Hospital Cancer Center
Biography

 

Stanley R. Hamilton, MD

City of Hope
Biography

 

David A. Mankoff, MD, PhD

University of Pennsylvania and the Abramson Cancer Center
Biography

 

Anthony F. Shields, MD, PhD

Wayne State University and the Barbara Ann Karmanos Cancer Institute
Biography