ECOG-ACRIN Leukemia Integrated Translational Science Center

This center brings together a team of outstanding researchers in both translational and clinical sciences who aim to transform the standard practice of leukemia care with the development of personalized diagnostic methods, biomarkers, and therapies. The ECOG-ACRIN Cancer Research Group (ECOG-ACRIN) established the center in 2019 with funding from the National Cancer Institute (NCI), part of the National Institutes of Health (NIH).

The center attracts junior and senior clinical investigators, laboratory scientists, computational biologists, biostatisticians, and other individuals to form synergistic cross-disciplinary research teams across the NCI's National Clinical Trials Network (NCTN). The center hosts two symposia per year in the spring and fall ECOG-ACRIN Group Meeting. It funds pilot projects and supports them with an extensive suite of scientific resources. Among its resource partners are the Memorial Sloan-Kettering Cancer Center's Marie-Joseé and Henry R. Kravis Center for Molecular Oncology and Center for Hematologic Malignancies. The New York Genome Center also contributes resources.

This center generates, coordinates, and leads translational studies in leukemia within ECOG-ACRIN and across the NCTN. In ECOG-ACRIN, it is the central hub for investigations by the Leukemia Laboratory Committee with support from ECOG-ACRIN's Leukemia Translational Research Laboratory, Leukemia Tissue Bank, and the Group's comprehensive Leukemia Data Warehouse. However, through all of these resources, ECOG-ACRIN is making major contributions to leukemia research across the entire NCTN. Read the NIH grant details.

Principal Investigators

Contact PI/
Project Leader

Ross L. Levine, MD

Memorial Sloan-Kettering Cancer Center

Leukemia Translational Science CenterLeukemia Translational Science Center

Ari M. Melnick, MD

Weill Cornell Medical College

Adolfo A. Ferrando, MD, PhD

Columbia University

ECOG-ACRIN Cancer Research Group