Trial Results Summaries

The ECOG-ACRIN Cancer Research Group (ECOG-ACRIN) strives to make the results of clinical trials available to the public in a standard, easy-to-read format. These summaries highlight ECOG-ACRIN studies, link to resources for more information, and acknowledge the vital contribution of trial participants to this research and improving patient care.

Below is the current listing of trial results summaries, with more to come. Hover over any of the column headings and click the up/down arrows to sort. You can also search by keyword. To access the summary for a particular trial, click on the trial name.

Cancer Type Trial Name Trial ID
Blood (Leukemia) Chemotherapy with or without Blinatumomab for B-Cell Acute Lymphoblastic Leukemia E1910
Blood (Leukemia) Ibrutinib-Rituximab or Chemoimmunotherapy for Chronic Lymphocytic Leukemia E1912
Blood (Leukemia) Simplified Patient Care Strategy in Decreasing Early Death in Patients with Acute Promyelocytic Leukemia EA9131
Blood (Lymphoma) Rituximab, Bendamustine Hydrochloride, and Bortezomib Followed by Rituximab and Lenalidomide in Treating Older Patients with Mantle Cell Lymphoma E1411
Blood (Lymphoma) Rituximab and Chemotherapy with or without Lenalidomide for Diffuse Large B-Cell Lymphoma E1412
Blood (Lymphoma) Bendamustine Hydrochloride and Rituximab with or without Bortezomib Followed by Rituximab with or without Lenalidomide in High-Risk Follicular Lymphoma E2408
Blood (Lymphoma) Combination of Immunotherapy and Targeted Chemotherapy in Relapsed Hodgkin Lymphoma E4412
Blood (Lymphoma) Rituximab with or without Stem Cell Transplant for Minimal Residual Disease-Negative Mantle Cell Lymphoma in First Complete Remission EA4151
Blood (Myeloma) Bortezomib or Carfilzomib with Lenalidomide and Dexamethasone in Treating Patients with Newly Diagnosed Multiple Myeloma E1A11
Blood (Myeloma) Lenalidomide and Dexamethasone With or Without Thalidomide in Treating Patients With Multiple Myeloma E4A03
Brain Radiation Therapy with or without Temozolomide for Symptomatic or Progressive Low-Grade Gliomas E3F05
Breast A Study to Evaluate Genetic Predictors of Aromatase Inhibitor Musculoskeletal Symptoms (AIMSS) E1Z11
Breast Exemestane with or without Entinostat for Patients with Recurrent Hormone Receptor-Positive Breast Cancer that is Locally Advanced or Metastatic E2112
Breast Value of Breast MRI to Treat Patients Diagnosed with Ductal Carcinoma In Situ E4112
Breast Doxorubicin, Cyclophosphamide, and Paclitaxel with or without Bevacizumab for Lymph Node-Positive or High-Risk, Lymph Node-Negative Breast Cancer E5103
Breast Testing Platinum-based Chemotherapy after Surgery in Triple-negative Breast Cancers EA1131
Breast Comparison of 3D Mammography to Abbreviated Breast MRI in Women with Dense Breasts EA1141
Breast Reducing Chemotherapy-Induced Neuropathy in African American Patients with Breast Cancer EAZ171
Breast Trial Assigning Individualized Options for Treatment TAILORx/PACCT-1
Colorectal Financial Burden Assessment in Patients with Stage 1-3 Colon or Rectal Cancer Undergoing Treatment EAQ162CD
Gastrointestinal and Pancreatic Neuroendocrine Tumors Testing if One Chemotherapy Combination is Better Than Another for High Grade Neuroendocrine Cancers EA2142
Head and Neck Chemotherapy with or without Bevacizumab for Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma E1305
Head and Neck Transoral Surgery and Low-Dose Radiation Therapy for Oropharynx Cancer E3311
Head and Neck Testing the Addition of Chemotherapy to the Treatment of Cancer of the Sinonasal Area EA3163
Kidney Pazopanib Hydrochloride in Treating Patients with Metastatic Kidney Cancer Who Have No Evidence of Disease After Surgery E2810
Kidney Testing the Addition of the Drug Nivolumab Before and After Surgery for Renal Cell Cancer PROSPER RCC/EA8143
Lung Testing the Addition of Nivolumab after Surgery for Non-Small Cell Lung Cancer ANVIL/EA5142
Lung Comparing Two Approaches to Using Antibody Therapy to Treat Stage 3 Non-Small Cell Lung Cancer Which Cannot Be Removed by Surgery EA5181
Melanoma (Skin) Ipilimumab or High-Dose Interferon Alfa-2b for Treating High-Risk Stage 3-4 Melanoma Removed by Surgery E1609
Melanoma (Skin) Testing the Therapy Sequence for Advanced BRAF Mutation Melanoma DREAMseq/EA6134
Melanoma (Skin) Testing Pembrolizumab vs Observation in Patients with Merkel Cell Carcinoma After Surgery STAMP/EA6174
Pancreas Comparing Two Treatment Combinations for Older Patients with Pancreatic Cancer that has Spread GIANT/EA2186
Pancreatic Neuroendocrine Tumors Temozolomide with or without Capecitabine for Treating Advanced Pancreatic Neuroendocrine Tumors E2211
Prostate Androgen Deprivation Therapy with or without Chemotherapy in Treating Metastatic Prostate Cancer CHAARTED/E3805
Prostate Testing the Addition of Cabazitaxel to Abiraterone for Metastatic Prostate Cancer in Patients Who Have Had Docetaxel CHAARTED2/EA8153
Various Engendering Reproductive Health Within Oncologic Survivorship EROS/E1Q11
Various Implementing a Virtual Tobacco Treatment in Community Oncology Practices (Smoke Free Support Study 2) EAQ171CD

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