Breast Active Clinical Trials

Numerous clinical trials are always active (ie, open and enrolling patients) in the ECOG-ACRIN Cancer Research Group, which focuses its research on adults who have or are at risk of developing cancer. The buttons below depict the general research categories being investigated in ECOG-ACRIN clinical trials. To access information within a particular category, click on the relevant button. Upon clicking, the color of the button will change from grey to red, and a table will appear on screen. The table will display the study number, study description, lead investigator(s), accrual goal, and the date participating institutions started to open the trial. Please read the ECOG-ACRIN Disclaimer in its entirety before accessing this information.

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To view educational materials, click on the links provided in the Educational Materials column. To send an email to the study chair, click on their name and a new email window will open.

Brain

Breast

Cancer Care Delivery Research

Cancer Control and Survivorship

Breast Cancer Trials Currently Recruiting Participants

STUDY	DESCRIPTION	ECOG-ACRIN STUDY CHAIR (STATISTICIAN)	ACCRUAL GOAL	DATE ACTIVATED	EDUCATIONAL MATERIALS
EA1131	A Randomized Phase III Post-Operative Trial of Platinum Based Chemotherapy vs. Observation in Patients with Residual Triple-Negative Basal-Like Breast Cancer following Neoadjuvant Chemotherapy	Ingrid A. Mayer, MD, MSCI, Chair Carlos L. Arteaga, MD, Co-Chair (Fengmin Zhao, PhD)	558	04/29/2016	EA1131 Resources
EA1151 aka TMIST	Tomosynthesis Mammographic Imaging Screening Trial (TMIST)	Etta D. Pisano, MD, Chair (Constantine A. Gatsonis, MD)	165000	07/06/2017	EA1151 Resources
EAI142	[18F] Fluoroestradiol (FES) PET as a Predictive Measure for Endocrine Therapy in Patients with Newly Diagnosed Metastatic Breast Cancer	Farrokh Dehdashti, MD, Co-Chair Hannah M. Linden, MD, FACP, Co-Chair Amy Fowler, MD, PhD, Junior Co-Chair Amy Clark, MD, MSCE, Junior Co-Chair (Zheng Zhang, PhD)	99	02/02/2016	EAI142 Resources
E2112	A Randomized Phase III Trial of Endocrine Therapy plus Entinostat or Placebo in Patients with Hormone Receptor-Positive Advanced Breast Cancer Note: This is an FDA registration trial	Roisin Connolly, MB, BCh, Chair Kathy D. Miller, MD, Co-Chair (Fengmin Zhao, PhD)	600	03/19/2014	E2112 Resources
6694, an imaging substudy for Alliance A011104	Effect of Preoperative Breast MRI on Surgical Outcomes, Costs and Quality of Life of Women with Breast Cancer	Christopher E. Comstock, MD, Chair (Eunhee Kim, PhD)	488	02/21/2014	6694 Resources

STUDY DESCRIPTION ECOG-ACRIN STUDY CHAIR
(STATISTICIAN) ACCRUAL
GOAL DATE
ACTIVATED EDUCATIONAL MATERIALS

EA1131 A Randomized Phase III Post-Operative Trial of Platinum Based Chemotherapy vs. Observation in Patients with Residual Triple-Negative Basal-Like Breast Cancer following Neoadjuvant Chemotherapy

Ingrid A. Mayer, MD, MSCI,
Chair
Carlos L. Arteaga, MD, Co-Chair
(Fengmin Zhao, PhD) 558 04/29/2016 EA1131 Resources

EA1151
aka
TMIST Tomosynthesis Mammographic Imaging Screening Trial (TMIST)
Etta D. Pisano, MD,
Chair
(Constantine A. Gatsonis, MD) 165000 07/06/2017 EA1151 Resources

EAI142 [18F] Fluoroestradiol (FES) PET as a Predictive Measure for Endocrine Therapy in Patients with Newly Diagnosed Metastatic Breast Cancer Farrokh Dehdashti, MD, Co-Chair
Hannah M. Linden, MD, FACP, Co-Chair
Amy Fowler, MD, PhD, Junior Co-Chair
Amy Clark, MD, MSCE, Junior Co-Chair
(Zheng Zhang, PhD) 99 02/02/2016 EAI142 Resources

E2112 A Randomized Phase III Trial of Endocrine Therapy plus Entinostat or Placebo in Patients with Hormone Receptor-Positive Advanced Breast Cancer

Note: This is an FDA registration trial Roisin Connolly, MB, BCh, Chair
Kathy D. Miller, MD, Co-Chair
(Fengmin Zhao, PhD) 600 03/19/2014 E2112 Resources

6694, an imaging substudy for Alliance A011104 Effect of Preoperative Breast MRI on Surgical Outcomes, Costs and Quality of Life of Women with Breast Cancer Christopher E. Comstock, MD,
Chair
(Eunhee Kim, PhD) 488 02/21/2014 6694 Resources

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