EA1151 – Tomosynthesis Mammography Imaging Screening Trial (TMIST)

The Tomosynthesis Mammography Imaging Screening Trial (TMIST), the first large-scale breast cancer screening trial in nearly 25 years, is approved for funding by the National Cancer Institute (NCI). The ECOG-ACRIN Cancer Research Group (ECOG-ACRIN), leading the trial, is now recruiting medical facilities as it prepares to open the trial in mid-2017.

TMIST will enroll 165,000 asymptomatic women in the US and Canada, between the ages of 45 and 74, to compare the incidence of advanced cancers in those screened for four years with digital breast tomosynthesis vs. standard digital mammography. The study aims to provide a modern basis for the continued use of mammography for breast cancer screening.

Physician and Research Staff Educational Materials:

Materials will be provided as they become available.