Blood Cancer

EA9131



Simplified Patient Care Strategy in Decreasing Early Death in Patients with Acute Promyelocytic Leukemia

STATUS: Closed to Accrual


This research trial studies how well simplified patient care strategy works in decreasing early death in patients with acute promyelocytic leukemia. Implementing simplified acute promyelocytic leukemia guidelines along with support from acute promyelocytic leukemia experts may decrease deaths and improve survival.
  • Confirmed to have a diagnosis of APL, which is defined as: * Positive t(15:17) by fluorescence in situ hybridization (FISH) OR * Positive t(15:17) by conventional karyotype, OR * Positive promyelocytic leukemia/retinoic acid receptor PML/RAR alpha by polymerase chain reaction (PCR)

  • Patients must accept treatment and supportive care guidelines

  • Referrals must be made as early as possible by treating physician (provider) but no later than 3 calendar days after ATRA or APL directed therapy is initiated; consent can be obtained up until day 7 after initiating APL directed therapy

  • Co-management can be started as soon as referral is made including weekends; the physician at the National Cancer Institute Community Oncology Research Program (NCORP) community facility should make every effort to call the APL expert at the first suspicion of APL

United States
AK
Fairbanks
Fairbanks Memorial Hospital
Contact: Site Public Contact
Email: Veronica.Stevenson@foundationhealth.org

CA
Anaheim
Kaiser Permanente-Anaheim
Contact: Site Public Contact
Email: clinical.trials@kp.org

Antioch
Kaiser Permanente-Deer Valley Medical Center
Contact: Site Public Contact
Email: Kpoct@kp.org

Baldwin Park
Kaiser Permanente-Baldwin Park
Contact: Site Public Contact
Email: clinical.trials@kp.org

Bellflower
Kaiser Permanente-Bellflower
Contact: Site Public Contact
Email: clinical.trials@kp.org

Fontana
Kaiser Permanente-Fontana
Contact: Site Public Contact
Email: clinical.trials@kp.org

Fremont
Kaiser Permanente-Fremont
Contact: Site Public Contact
Email: Kpoct@kp.org

Fresno
Fresno Cancer Center
Contact: Site Public Contact
Email: Kpoct@kp.org

Kaiser Permanente-Fresno
Contact: Site Public Contact
Email: Kpoct@kp.org

Harbor City
Kaiser Permanente - Harbor City
Contact: Site Public Contact
Email: clinical.trials@kp.org

Irvine
Kaiser Permanente-Irvine
Contact: Site Public Contact
Email: clinical.trials@kp.org

Los Angeles
Kaiser Permanente Los Angeles Medical Center
Contact: Site Public Contact
Email: clinical.trials@kp.org

Kaiser Permanente West Los Angeles
Contact: Site Public Contact
Email: clinical.trials@kp.org

Modesto
Kaiser Permanente-Modesto
Contact: Site Public Contact
Email: Kpoct@kp.org

Oakland
Kaiser Permanente Oakland-Broadway
Contact: Site Public Contact
Email: Kpoct@kp.org

Kaiser Permanente-Oakland
Contact: Site Public Contact
Email: Kpoct@kp.org

Ontario
Kaiser Permanente-Ontario
Contact: Site Public Contact
Email: clinical.trials@kp.org

Panorama City
Kaiser Permanente - Panorama City
Contact: Site Public Contact
Email: clinical.trials@kp.org

Rancho Cordova
Kaiser Permanente-Rancho Cordova Cancer Center
Contact: Site Public Contact
Email: Kpoct@kp.org

Redwood City
Kaiser Permanente- Marshall Medical Offices
Contact: Site Public Contact

Kaiser Permanente-Redwood City
Contact: Site Public Contact
Email: Kpoct@kp.org

Richmond
Kaiser Permanente-Richmond
Contact: Site Public Contact
Email: Kpoct@kp.org

Riverside
Kaiser Permanente-Riverside
Contact: Site Public Contact
Email: clinical.trials@kp.org

Rohnert Park
Rohnert Park Cancer Center
Contact: Site Public Contact
Email: Kpoct@kp.org

Roseville
Kaiser Permanente-Roseville
Contact: Site Public Contact
Email: Kpoct@kp.org

The Permanente Medical Group-Roseville Radiation Oncology
Contact: Site Public Contact
Email: Kpoct@kp.org

Sacramento
Kaiser Permanente - Sacramento
Contact: Site Public Contact
Email: Kpoct@kp.org

Kaiser Permanente Downtown Commons
Contact: Site Public Contact
Email: kpoct@kp.org

Kaiser Permanente-South Sacramento
Contact: Site Public Contact
Email: Kpoct@kp.org

South Sacramento Cancer Center
Contact: Site Public Contact
Email: Kpoct@kp.org

San Diego
Kaiser Permanente-San Diego Mission
Contact: Site Public Contact
Email: clinical.trials@kp.org

Kaiser Permanente-San Diego Zion
Contact: Site Public Contact
Email: clinical.trials@kp.org

San Francisco
Kaiser Permanente-San Francisco
Contact: Site Public Contact
Email: Kpoct@kp.org

San Jose
Kaiser Permanente-Santa Teresa-San Jose
Contact: Site Public Contact
Email: Kpoct@kp.org

San Leandro
Kaiser Permanente San Leandro
Contact: Site Public Contact
Email: Kpoct@kp.org

San Marcos
Kaiser Permanente-San Marcos
Contact: Site Public Contact
Email: clinical.trials@kp.org

San Rafael
Kaiser San Rafael-Gallinas
Contact: Site Public Contact
Email: Kpoct@kp.org

Santa Clara
Kaiser Permanente Medical Center - Santa Clara
Contact: Site Public Contact
Email: Kpoct@kp.org

Santa Rosa
Kaiser Permanente-Santa Rosa
Contact: Site Public Contact
Email: Kpoct@kp.org

South San Francisco
Kaiser Permanente Cancer Treatment Center
Contact: Site Public Contact
Email: Kpoct@kp.org

Kaiser Permanente-South San Francisco
Contact: Site Public Contact
Email: Kpoct@kp.org

Stockton
Kaiser Permanente-Stockton
Contact: Site Public Contact
Email: Kpoct@kp.org

Vacaville
Kaiser Permanente Medical Center-Vacaville
Contact: Site Public Contact
Email: Kpoct@kp.org

Vallejo
Kaiser Permanente-Vallejo
Contact: Site Public Contact
Email: Kpoct@kp.org

Walnut Creek
Kaiser Permanente-Walnut Creek
Contact: Site Public Contact
Email: Kpoct@kp.org

Woodland Hills
Kaiser Permanente-Woodland Hills
Contact: Site Public Contact
Email: clinical.trials@kp.org

CO
Aurora
Rocky Mountain Cancer Centers-Aurora
Contact: Site Public Contact
Email: info@westernstatesncorp.org

The Medical Center of Aurora
Contact: Site Public Contact
Email: info@westernstatesncorp.org

Boulder
Boulder Community Foothills Hospital
Contact: Site Public Contact
Email: info@westernstatesncorp.org

Boulder Community Hospital
Contact: Site Public Contact
Email: jbloomfield@co-cancerresearch.org

Rocky Mountain Cancer Centers-Boulder
Contact: Site Public Contact
Email: info@westernstatesncorp.org

Centennial
Rocky Mountain Cancer Centers - Centennial
Contact: Site Public Contact
Email: info@westernstatesncorp.org

Denver
Cancer Center of Colorado at Sloan's Lake
Contact: Site Public Contact

Colorado Blood Cancer Institute
Contact: Site Public Contact
Email: info@westernstatesncorp.org

Denver Health Medical Center
Contact: Site Public Contact
Email: ccrp@co-cancerresearch.org

National Jewish Health-Main Campus
Contact: Site Public Contact
Email: glicht@co-cancerresearch.org

Presbyterian - Saint Lukes Medical Center - Health One
Contact: Site Public Contact
Email: info@westernstatesncorp.org

Rocky Mountain Cancer Centers-Midtown
Contact: Site Public Contact
Email: info@westernstatesncorp.org

Rocky Mountain Cancer Centers-Rose
Contact: Site Public Contact
Email: info@westernstatesncorp.org

Rose Medical Center
Contact: Site Public Contact
Email: ccrp@co-cancerresearch.org

SCL Health Saint Joseph Hospital
Contact: Site Public Contact
Email: info@westernstatesncorp.org

The Women's Imaging Center
Contact: Site Public Contact
Email: info@westernstatesncorp.org

Englewood
Mountain Blue Cancer Care Center - Swedish
Contact: Site Public Contact
Email: info@westernstatesncorp.org

Swedish Medical Center
Contact: Site Public Contact
Email: info@westernstatesncorp.org

Golden
National Jewish Health-Western Hematology Oncology
Contact: Site Public Contact
Email: glicht@co-cancerresearch.org

Grand Junction
Saint Mary's Hospital and Regional Medical Center
Contact: Site Public Contact
Email: ccrp@co-cancerresearch.org

Greeley
North Colorado Medical Center
Contact: Site Public Contact
Email: info@westernstatesncorp.org

Greenwood Village
Rocky Mountain Cancer Centers-Greenwood Village
Contact: Site Public Contact
Email: info@westernstatesncorp.org

Lafayette
Good Samaritan Medical Center
Contact: Site Public Contact

Littleton
Rocky Mountain Cancer Centers-Littleton
Contact: Site Public Contact
Email: info@westernstatesncorp.org

Lone Tree
Rocky Mountain Cancer Centers-Sky Ridge
Contact: Site Public Contact
Email: info@westernstatesncorp.org

Sky Ridge Medical Center
Contact: Site Public Contact
Email: info@westernstatesncorp.org

Loveland
McKee Medical Center
Contact: Site Public Contact
Email: info@westernstatesncorp.org

Thornton
National Jewish Health-Northern Hematology Oncology
Contact: Site Public Contact
Email: glicht@co-cancerresearch.org

Wheat Ridge
SCL Health Lutheran Medical Center
Contact: Site Public Contact
Email: ccrp@co-cancerresearch.org

FL
Jacksonville
Mayo Clinic in Florida
Contact: Site Public Contact

GA
Albany
Phoebe Putney Memorial Hospital
Contact: Site Public Contact
Email: ga_cares@augusta.edu

Athens
University Cancer and Blood Center LLC
Contact: Site Public Contact
Email: research@universitycancer.com

Augusta
Augusta University Medical Center
Contact: Site Public Contact
Email: ga_cares@augusta.edu

Decatur
Dekalb Medical Center
Contact: Site Public Contact
Email: clinicaltrialsoncology@dekalbmedical.org

Savannah
Lewis Cancer and Research Pavilion at Saint Joseph's/Candler
Contact: Site Public Contact
Email: underberga@sjchs.org

Low Country Cancer Care
Contact: Site Public Contact
Email: Lorraine.OHara@hcahealthcare.com

Summit Cancer Care-Candler
Contact: Site Public Contact
Email: ecog.rss@jimmy.harvard.edu

HI
Honolulu
Kaiser Permanente Moanalua Medical Center
Contact: Site Public Contact
Email: shelley.a.clark@kp.org

IA
Ames
Mary Greeley Medical Center
Contact: Site Public Contact

McFarland Clinic PC - Ames
Contact: Site Public Contact
Email: ksoder@mcfarlandclinic.com

Boone
McFarland Clinic PC-Boone
Contact: Site Public Contact

Fort Dodge
McFarland Clinic PC-Trinity Cancer Center
Contact: Site Public Contact

Jefferson
McFarland Clinic PC-Jefferson
Contact: Site Public Contact

Marshalltown
McFarland Clinic PC-Marshalltown
Contact: Site Public Contact

Sioux City
Siouxland Regional Cancer Center
Contact: Site Public Contact
Email: HoopingarnerT@jencc.com

IL
Bloomington
Illinois CancerCare-Bloomington
Contact: Site Public Contact
Email: andersonj@illinoiscancercare.com

Canton
Illinois CancerCare-Canton
Contact: Site Public Contact
Email: andersonj@illinoiscancercare.com

Carbondale
Memorial Hospital of Carbondale
Contact: Site Public Contact
Email: clinical.research@sih.net

Carterville
SIH Cancer Institute
Contact: Site Public Contact
Email: clinical.research@sih.net

Carthage
Illinois CancerCare-Carthage
Contact: Site Public Contact
Email: andersonj@illinoiscancercare.com

Centralia
Centralia Oncology Clinic
Contact: Site Public Contact
Email: rhamrick@dmhhs.org

Chicago
John H Stroger Jr Hospital of Cook County
Contact: Site Public Contact

Northwestern University
Contact: Site Public Contact
Email: cancer@northwestern.edu

Decatur
Cancer Care Specialists of Illinois - Decatur
Contact: Site Public Contact
Email: rhamrick@dmhhs.org

Decatur Memorial Hospital
Contact: Site Public Contact
Email: rhamrick@dmhhs.org

Dixon
Illinois CancerCare-Dixon
Contact: Site Public Contact

Effingham
Crossroads Cancer Center
Contact: Site Public Contact
Email: rhamrick@dmhhs.org

Eureka
Illinois CancerCare-Eureka
Contact: Site Public Contact
Email: andersonj@illinoiscancercare.com

Galesburg
Illinois CancerCare-Galesburg
Contact: Site Public Contact
Email: andersonj@illinoiscancercare.com

Western Illinois Cancer Treatment Center
Contact: Site Public Contact

Kewanee
Illinois CancerCare-Kewanee Clinic
Contact: Site Public Contact
Email: andersonj@illinoiscancercare.com

Macomb
Illinois CancerCare-Macomb
Contact: Site Public Contact
Email: andersonj@illinoiscancercare.com

O'Fallon
Cancer Care Center of O'Fallon
Contact: Site Public Contact
Email: morganthaler.jodi@mhsil.com

Ottawa
Illinois CancerCare-Ottawa Clinic
Contact: Site Public Contact
Email: andersonj@illinoiscancercare.com

Pekin
Illinois CancerCare-Pekin
Contact: Site Public Contact
Email: andersonj@illinoiscancercare.com

OSF Saint Francis Radiation Oncology at Pekin Cancer Treatment Center
Contact: Site Public Contact
Email: andersonj@illinoiscancercare.com

Peoria
Illinois CancerCare-Peoria
Contact: Site Public Contact
Email: andersonj@illinoiscancercare.com

Methodist Medical Center of Illinois
Contact: Site Public Contact
Email: andersonj@illinoiscancercare.com

OSF Saint Francis Medical Center
Contact: Site Public Contact
Email: andersonj@illinoiscancercare.com

OSF Saint Francis Radiation Oncology at Peoria Cancer Center
Contact: Site Public Contact
Email: andersonj@illinoiscancercare.com

Peru
Illinois CancerCare-Peru
Contact: Site Public Contact
Email: andersonj@illinoiscancercare.com

Valley Radiation Oncology
Contact: Site Public Contact

Princeton
Illinois CancerCare-Princeton
Contact: Site Public Contact
Email: andersonj@illinoiscancercare.com

Springfield
Memorial Medical Center
Contact: Site Public Contact

Southern Illinois University School of Medicine
Contact: Site Public Contact

Springfield Clinic
Contact: Site Public Contact

Swansea
Southwest Illinois Health Services LLP
Contact: Site Public Contact
Email: lynns@thecancercenter.com

KS
Chanute
Cancer Center of Kansas - Chanute
Contact: Site Public Contact
Email: Keisha.humphries@ascension.org

Dodge City
Cancer Center of Kansas - Dodge City
Contact: Site Public Contact
Email: Keisha.humphries@ascension.org

El Dorado
Cancer Center of Kansas - El Dorado
Contact: Site Public Contact
Email: Keisha.humphries@ascension.org

Fort Scott
Cancer Center of Kansas - Fort Scott
Contact: Site Public Contact
Email: Keisha.humphries@ascension.org

Garden City
Central Care Cancer Center - Garden City
Contact: Site Public Contact
Email: aroland@kccop.org

Great Bend
Central Care Cancer Center - Great Bend
Contact: Site Public Contact
Email: aroland@kccop.org

Independence
Cancer Center of Kansas-Independence
Contact: Site Public Contact
Email: Keisha.humphries@ascension.org

Kingman
Cancer Center of Kansas-Kingman
Contact: Site Public Contact
Email: Keisha.humphries@ascension.org

Lawrence
Lawrence Memorial Hospital
Contact: Site Public Contact
Email: Stephanie.Norris@LMH.ORG

Lenexa
Kansas Institute of Medicine Cancer and Blood Center
Contact: Site Public Contact
Email: aroland@kccop.org

Minimally Invasive Surgery Hospital
Contact: Site Public Contact
Email: aroland@kccop.org

Liberal
Cancer Center of Kansas-Liberal
Contact: Site Public Contact
Email: Keisha.humphries@ascension.org

Manhattan
Cancer Center of Kansas-Manhattan
Contact: Site Public Contact
Email: Keisha.humphries@ascension.org

McPherson
Cancer Center of Kansas - McPherson
Contact: Site Public Contact
Email: Keisha.humphries@ascension.org

Newton
Cancer Center of Kansas - Newton
Contact: Site Public Contact
Email: Keisha.humphries@ascension.org

Overland Park
Menorah Medical Center
Contact: Site Public Contact
Email: aroland@kccop.org

Parsons
Cancer Center of Kansas - Parsons
Contact: Site Public Contact
Email: Keisha.humphries@ascension.org

Pratt
Cancer Center of Kansas - Pratt
Contact: Site Public Contact
Email: Keisha.humphries@ascension.org

Salina
Cancer Center of Kansas - Salina
Contact: Site Public Contact
Email: Keisha.humphries@ascension.org

Wellington
Cancer Center of Kansas - Wellington
Contact: Site Public Contact
Email: Keisha.humphries@ascension.org

Wichita
Ascension Via Christi Hospitals Wichita
Contact: Site Public Contact
Email: Keisha.humphries@ascension.org

Associates In Womens Health
Contact: Site Public Contact
Email: Keisha.humphries@ascension.org

Cancer Center of Kansas - Wichita
Contact: Site Public Contact
Email: Keisha.humphries@ascension.org

Cancer Center of Kansas-Wichita Medical Arts Tower
Contact: Site Public Contact
Email: Keisha.humphries@ascension.org

Wesley Medical Center
Contact: Site Public Contact
Email: Keisha.humphries@ascension.org

Winfield
Cancer Center of Kansas - Winfield
Contact: Site Public Contact
Email: Keisha.humphries@ascension.org

LA
New Orleans
Ochsner Medical Center Jefferson
Contact: Site Public Contact
Email: Gregory.Johnstone@ochsner.org

MN
Aitkin
Riverwood Healthcare Center
Contact: Site Public Contact
Email: CancerTrials@EssentiaHealth.org

Bemidji
Sanford Joe Lueken Cancer Center
Contact: Site Public Contact
Email: OncologyClinicalTrialsFargo@sanfordhealth.org

Brainerd
Essentia Health Saint Joseph's Medical Center
Contact: Site Public Contact
Email: CancerTrials@EssentiaHealth.org

Burnsville
Fairview Ridges Hospital
Contact: Site Public Contact
Email: mmcorc@healthpartners.com

Minnesota Oncology - Burnsville
Contact: Site Public Contact
Email: mmcorc@healthpartners.com

Cambridge
Cambridge Medical Center
Contact: Site Public Contact
Email: mmcorc@healthpartners.com

Coon Rapids
Mercy Hospital
Contact: Site Public Contact
Email: mmcorc@healthpartners.com

Deer River
Essentia Health - Deer River Clinic
Contact: Site Public Contact
Email: CancerTrials@EssentiaHealth.org

Detroit Lakes
Essentia Health Saint Mary's - Detroit Lakes Clinic
Contact: Site Public Contact
Email: CancerTrials@EssentiaHealth.org

Duluth
Essentia Health Cancer Center
Contact: Site Public Contact
Email: CancerTrials@EssentiaHealth.org

Essentia Health Saint Mary's Medical Center
Contact: Site Public Contact
Email: CancerTrials@EssentiaHealth.org

Miller-Dwan Hospital
Contact: Site Public Contact
Email: CancerTrials@EssentiaHealth.org

Edina
Fairview Southdale Hospital
Contact: Site Public Contact
Email: mmcorc@healthpartners.com

Fergus Falls
Lake Region Healthcare Corporation-Cancer Care
Contact: Site Public Contact
Email: CancerTrials@EssentiaHealth.org

Fosston
Essentia Health - Fosston
Contact: Site Public Contact
Email: CancerTrials@EssentiaHealth.org

Fridley
Unity Hospital
Contact: Site Public Contact
Email: mmcorc@healthpartners.com

Hibbing
Essentia Health Hibbing Clinic
Contact: Site Public Contact

Maple Grove
Fairview Clinics and Surgery Center Maple Grove
Contact: Site Public Contact
Email: mmcorc@healthpartners.com

Maplewood
Minnesota Oncology Hematology PA-Maplewood
Contact: Site Public Contact
Email: mmcorc@healthpartners.com

Saint John's Hospital - Healtheast
Contact: Site Public Contact
Email: mmcorc@healthpartners.com

Minneapolis
Abbott-Northwestern Hospital
Contact: Site Public Contact
Email: mmcorc@healthpartners.com

Health Partners Inc
Contact: Site Public Contact
Email: mmcorc@healthpartners.com

Hennepin County Medical Center
Contact: Site Public Contact
Email: mmcorc@healthpartners.com

Monticello
Monticello Cancer Center
Contact: Site Public Contact
Email: mmcorc@healthpartners.com

New Ulm
New Ulm Medical Center
Contact: Site Public Contact
Email: mmcorc@healthpartners.com

Park Rapids
Essentia Health - Park Rapids
Contact: Site Public Contact
Email: CancerTrials@EssentiaHealth.org

Princeton
Fairview Northland Medical Center
Contact: Site Public Contact
Email: mmcorc@healthpartners.com

Robbinsdale
North Memorial Medical Health Center
Contact: Site Public Contact
Email: mmcorc@healthpartners.com

Rochester
Mayo Clinic in Rochester
Contact: Site Public Contact

Saint Louis Park
Park Nicollet Clinic - Saint Louis Park
Contact: Site Public Contact
Email: mmcorc@healthpartners.com

Saint Paul
Regions Hospital
Contact: Site Public Contact
Email: mmcorc@healthpartners.com

United Hospital
Contact: Site Public Contact
Email: mmcorc@healthpartners.com

Sandstone
Essentia Health Sandstone
Contact: Site Public Contact
Email: CancerTrials@EssentiaHealth.org

Shakopee
Saint Francis Regional Medical Center
Contact: Site Public Contact
Email: mmcorc@healthpartners.com

Stillwater
Lakeview Hospital
Contact: Site Public Contact
Email: mmcorc@healthpartners.com

Thief River Falls
Sanford Thief River Falls Medical Center
Contact: Site Public Contact

Virginia
Essentia Health Virginia Clinic
Contact: Site Public Contact
Email: CancerTrials@EssentiaHealth.org

Waconia
Ridgeview Medical Center
Contact: Site Public Contact
Email: mmcorc@healthpartners.com

Willmar
Rice Memorial Hospital
Contact: Site Public Contact
Email: mmcorc@healthpartners.com

Woodbury
Minnesota Oncology Hematology PA-Woodbury
Contact: Site Public Contact
Email: mmcorc@healthpartners.com

Worthington
Sanford Cancer Center Worthington
Contact: Site Public Contact

Wyoming
Fairview Lakes Medical Center
Contact: Site Public Contact
Email: mmcorc@healthpartners.com

MO
Bolivar
Central Care Cancer Center - Bolivar
Contact: Site Public Contact
Email: aroland@kccop.org

Bonne Terre
Parkland Health Center-Bonne Terre
Contact: Site Public Contact

Cape Girardeau
Saint Francis Medical Center
Contact: Site Public Contact
Email: sfmc@sfmc.net

Southeast Cancer Center
Contact: Site Public Contact

Farmington
Parkland Health Center - Farmington
Contact: Site Public Contact

Independence
Centerpoint Medical Center LLC
Contact: Site Public Contact
Email: aroland@kccop.org

Jefferson City
Capital Region Southwest Campus
Contact: Site Public Contact
Email: swooden@mail.crmc.org

Kansas City
Research Medical Center
Contact: Site Public Contact
Email: aroland@kccop.org

Saint Louis
Missouri Baptist Medical Center
Contact: Site Public Contact

Sainte Genevieve
Sainte Genevieve County Memorial Hospital
Contact: Site Public Contact

Sullivan
Missouri Baptist Sullivan Hospital
Contact: Site Public Contact

Sunset Hills
Missouri Baptist Outpatient Center-Sunset Hills
Contact: Site Public Contact

MT
Billings
Saint Vincent Frontier Cancer Center
Contact: Site Public Contact

Saint Vincent Healthcare
Contact: Site Public Contact
Email: mccinfo@mtcancer.org

Butte
Saint James Community Hospital and Cancer Treatment Center
Contact: Site Public Contact

NC
Asheville
AdventHealth Infusion Center Asheville
Contact: Site Public Contact
Email: AMBER.WHEELER@AdventHealth.com

Clyde
AdventHealth Infusion Center Haywood
Contact: Site Public Contact
Email: AMBER.WHEELER@AdventHealth.com

Hendersonville
AdventHealth Hendersonville
Contact: Site Public Contact
Email: AMBER.WHEELER@AdventHealth.com

Weaverville
AdventHealth Infusion Center Weaverville
Contact: Site Public Contact
Email: AMBER.WHEELER@AdventHealth.com

ND
Bismarck
Sanford Bismarck Medical Center
Contact: Site Public Contact
Email: OncologyClinicalTrialsFargo@sanfordhealth.org

Fargo
Essentia Health Cancer Center-South University Clinic
Contact: Site Public Contact
Email: CancerTrials@EssentiaHealth.org

Sanford Broadway Medical Center
Contact: Site Public Contact
Email: OncologyClinicalTrialsFargo@sanfordhealth.org

Sanford Roger Maris Cancer Center
Contact: Site Public Contact
Email: OncologyClinicalTrialsFargo@sanfordhealth.org

Sanford South University Medical Center
Contact: Site Public Contact

Jamestown
Essentia Health - Jamestown Clinic
Contact: Site Public Contact
Email: CancerTrials@EssentiaHealth.org

NY
New York
Memorial Sloan Kettering Cancer Center
Contact: Site Public Contact

PA
Bryn Mawr
Bryn Mawr Hospital
Contact: Site Public Contact
Email: turzoe@mlhs.org

Collegeville
Main Line Health Center-Collegeville
Contact: Site Public Contact
Email: turzoe@mlhs.org

Danville
Geisinger Medical Center
Contact: Site Public Contact
Email: HemonCCTrials@geisinger.edu

Exton
Main Line Health Center-Exton
Contact: Site Public Contact
Email: turzoe@mlhs.org

Media
Riddle Memorial Hospital
Contact: Site Public Contact
Email: turzoe@mlhs.org

Paoli
Paoli Memorial Hospital
Contact: Site Public Contact
Email: turzoe@mlhs.org

Philadelphia
University of Pennsylvania/Abramson Cancer Center
Contact: Site Public Contact

Wynnewood
Lankenau Medical Center
Contact: Site Public Contact
Email: turzoe@mlhs.org

PR
Aguadilla
Advance Oncology Center
Contact: Site Public Contact

Arecibo
Doctor's Cancer Center-Arecibo
Contact: Site Public Contact

Bayamon
Cancer Center-Metro Medical Center Bayamon
Contact: Site Public Contact

Hematologia Oncologia San Pablo
Contact: Site Public Contact

Caguas
HIMA San Pablo Oncologic Hospital
Contact: Site Public Contact

Manati
Doctors Cancer Center
Contact: Site Public Contact

Ponce
Instituto Oncologia Moderna Ponce
Contact: Site Public Contact

San Juan
Centro Comprensivo de Cancer de UPR
Contact: Site Public Contact
Email: ecog.rss@jimmy.harvard.edu

Primary Care Physician Group
Contact: Site Public Contact

San Juan City Hospital
Contact: Site Public Contact

San Juan Community Oncology Group
Contact: Site Public Contact

Santa Isabel
Centro de Hematologia y Oncologia del Sur
Contact: Site Public Contact

SC
Gaffney
Gibbs Cancer Center-Gaffney
Contact: Site Public Contact
Email: kmertz-rivera@gibbscc.org

Greenville
Saint Francis Cancer Center
Contact: Site Public Contact
Email: melissa_beckman@bshsi.org

Saint Francis Hospital
Contact: Site Public Contact
Email: melissa_beckman@bshsi.org

Greer
Gibbs Cancer Center-Pelham
Contact: Site Public Contact
Email: kmertz-rivera@gibbscc.org

Spartanburg
Spartanburg Medical Center
Contact: Site Public Contact
Email: kmertz-rivera@gibbscc.org

Union
MGC Hematology Oncology-Union
Contact: Site Public Contact
Email: kmertz-rivera@gibbscc.org

SD
Sioux Falls
Sanford Cancer Center Oncology Clinic
Contact: Site Public Contact
Email: OncologyClinicTrialsSF@sanfordhealth.org

Sanford USD Medical Center - Sioux Falls
Contact: Site Public Contact
Email: OncologyClinicalTrialsSF@SanfordHealth.org

TN
Memphis
Baptist Memorial Hospital and Cancer Center-Memphis
Contact: Site Public Contact
Email: BCCclintrials@bmhcc.org

UT
American Fork
American Fork Hospital / Huntsman Intermountain Cancer Center
Contact: Site Public Contact
Email: officeofresearch@imail.org

Cedar City
Sandra L Maxwell Cancer Center
Contact: Site Public Contact
Email: officeofresearch@imail.org

Logan
Logan Regional Hospital
Contact: Site Public Contact
Email: officeofresearch@imail.org

Murray
Intermountain Medical Center
Contact: Site Public Contact
Email: officeofresearch@imail.org

Ogden
McKay-Dee Hospital Center
Contact: Site Public Contact
Email: officeofresearch@imail.org

Provo
Utah Valley Regional Medical Center
Contact: Site Public Contact
Email: officeofresearch@imail.org

Riverton
Riverton Hospital
Contact: Site Public Contact
Email: officeofresearch@imail.org

Saint George
Saint George Regional Medical Center
Contact: Site Public Contact
Email: officeofresearch@imail.org

Salt Lake City
LDS Hospital
Contact: Site Public Contact
Email: officeofresearch@imail.org

Utah Cancer Specialists-Salt Lake City
Contact: Site Public Contact
Email: officeofresearch@imail.org

WI
Appleton
ThedaCare Regional Cancer Center
Contact: Site Public Contact
Email: ResearchDept@thedacare.org

Ashland
Duluth Clinic Ashland
Contact: Site Public Contact
Email: CancerTrials@EssentiaHealth.org

Northwest Wisconsin Cancer Center
Contact: Site Public Contact
Email: CancerTrials@EssentiaHealth.org

Burlington
Aurora Cancer Care-Southern Lakes VLCC
Contact: Site Public Contact
Email: ncorp@aurora.org

Cudahy
Aurora Saint Luke's South Shore
Contact: Site Public Contact
Email: ncorp@aurora.org

Eau Claire
Marshfield Medical Center-EC Cancer Center
Contact: Site Public Contact
Email: oncology.clinical.trials@marshfieldresearch.org

Fond Du Lac
Aurora Health Center-Fond du Lac
Contact: Site Public Contact
Email: ncorp@aurora.org

Germantown
Aurora Health Care Germantown Health Center
Contact: Site Public Contact
Email: ncorp@aurora.org

Grafton
Aurora Cancer Care-Grafton
Contact: Site Public Contact
Email: ncorp@aurora.org

Green Bay
Aurora BayCare Medical Center
Contact: Site Public Contact
Email: ncorp@aurora.org

Kenosha
Aurora Cancer Care-Kenosha South
Contact: Site Public Contact
Email: ncorp@aurora.org

La Crosse
Gundersen Lutheran Medical Center
Contact: Site Public Contact
Email: cancerctr@gundersenhealth.org

Marinette
Aurora Bay Area Medical Group-Marinette
Contact: Site Public Contact
Email: ncorp@aurora.org

Marshfield
Marshfield Medical Center-Marshfield
Contact: Site Public Contact
Email: oncology.clinical.trials@marshfieldresearch.org

Milwaukee
Aurora Cancer Care-Milwaukee
Contact: Site Public Contact
Email: ncorp@aurora.org

Aurora Saint Luke's Medical Center
Contact: Site Public Contact
Email: ncorp@aurora.org

Aurora Sinai Medical Center
Contact: Site Public Contact
Email: ncorp@aurora.org

Minocqua
Marshfield Clinic-Minocqua Center
Contact: Site Public Contact
Email: oncology.clinical.trials@marshfieldresearch.org

New Richmond
Cancer Center of Western Wisconsin
Contact: Site Public Contact
Email: mmcorc@healthpartners.com

Oshkosh
Vince Lombardi Cancer Clinic - Oshkosh
Contact: Site Public Contact
Email: ncorp@aurora.org

Racine
Aurora Cancer Care-Racine
Contact: Site Public Contact
Email: ncorp@aurora.org

Rice Lake
Lakeview Medical Center-Marshfield Clinic
Contact: Site Public Contact
Email: oncology.clinical.trials@marshfieldresearch.org

Marshfield Medical Center-Rice Lake
Contact: Site Public Contact
Email: oncology.clinical.trials@marshfieldresearch.org

Sheboygan
Vince Lombardi Cancer Clinic-Sheboygan
Contact: Site Public Contact
Email: ncorp@aurora.org

Stevens Point
Marshfield Medical Center-River Region at Stevens Point
Contact: Site Public Contact
Email: oncology.clinical.trials@marshfieldresearch.org

Summit
Aurora Medical Center in Summit
Contact: Site Public Contact
Email: ncorp@aurora.org

Two Rivers
Vince Lombardi Cancer Clinic-Two Rivers
Contact: Site Public Contact
Email: ncorp@aurora.org

Wauwatosa
Aurora Cancer Care-Milwaukee West
Contact: Site Public Contact
Email: ncorp@aurora.org

West Allis
Aurora West Allis Medical Center
Contact: Site Public Contact
Email: ncorp@aurora.org

Weston
Marshfield Medical Center - Weston
Contact: Site Public Contact
Email: oncology.clinical.trials@marshfieldresearch.org

WY
Cheyenne
Cheyenne Regional Medical Center-West
Contact: Site Public Contact
Email: ccrp@co-cancerresearch.org

PRIMARY OBJECTIVES:
I. To evaluate if the proposed patient care strategy, that includes use of simplified guidelines along with acute promyelocytic leukemia (APL) expert support, decreases the one-month induction mortality rate from 30% to under 15%.

SECONDARY OBJECTIVES:
I. To assess the overall survival 1 year after accrual is completed.
II. To assess incidence and severity of differentiation syndrome.
III. To correlate outcomes with time to initiation of all-trans retinoic acid (ATRA) from diagnosis or suspicion of diagnosis.
IV. To compare outcomes between academic and community centers separately.
V. To evaluate factors associated with outcome.

OUTLINE:
Patients receive standard of care treatment for APL. Patientsโ€™ doctors regularly discuss with an APL expert to identify and mange treatment.

After diagnosis, patients are followed up for 1 year.

Interactive content above is from the official study record on the National Cancer Institute website, cancer.gov.


The ECOG-ACRIN Cancer Research Group designed and conducted this trial with funding from the National Cancer Institute through its National Clinical Trials Network.


EA9131 (Closed)
ECOG-ACRIN Cancer Research Group