Prostate Cancer

EA8153 / CHAARTED2



Abiraterone Acetate and Antiandrogen Therapy with or without Cabazitaxel and Prednisone in Treating Patients with Metastatic, Castration-Resistant Prostate Cancer Previously Treated with Docetaxel

STATUS: Closed to Accrual


This randomized phase II trial studies how well abiraterone acetate and antiandrogen therapy, with or without cabazitaxel and prednisone, work in treating patients with castration-resistant prostate cancer previously treated with docetaxel that has spread to other parts of the body. Androgens can cause the growth of prostate cancer cells. Hormone therapy using abiraterone acetate and antiandrogen therapy may fight prostate cancer by lowering and / or blocking the use of androgens by the tumor cells. Drugs used in chemotherapy, such as cabazitaxel, work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. Anti-inflammatory drugs, such as prednisone lower the bodyโ€™s immune response and are used with other drugs in the treatment of some types of cancer. Giving abiraterone acetate and antiandrogen therapy with or without cabazitaxel and prednisone may help kill more tumor cells.
  • Histologically confirmed diagnosis of prostate cancer (adenocarcinoma of the prostate)

  • Previous chemotherapy with at least 3 cycles of docetaxel for hormone-sensitive metastatic prostate cancer

  • Metastatic disease as evidenced by the presence of soft tissue and/or bone metastases on imaging studies (CT/magnetic resonance imaging [MRI] of abdomen/pelvis, bone scintigraphy or NaF PET/CT)

  • Ability to swallow abiraterone acetate tablets as a whole

  • All patients must be receiving standard of care androgen deprivation treatment (surgical castration versus LHRH agonist or antagonist treatment); subjects receiving LHRH agonist or antagonist must continue treatment throughout the time on this study

  • Patients must have castrate serum level of testosterone of < 50 ng/dL (< 1.73 nmol/L), confirmed =< 4 weeks prior to randomization

  • Patients must have progressive disease while receiving androgen deprivation therapy defined by any one of the following as per the Prostate Cancer Clinical Trials Working Group 3 (PCWG3) criteria for PSA, measurable disease or non-measurable (bone) disease during treatment with ADT: * PSA: At least two consecutive rises in serum PSA, obtained at a minimum of 1-week intervals, with the final value >= 1.0 ng/mL, confirmed =< 4 weeks prior to randomization OR * Measurable disease (by RECIST 1.1): > 20% increase in the sum of the longest diameters of all measurable lesions or the development of new measurable lesions; the short axis of a target lymph node must be more that 15 mm to be assessed for change in size OR * Non-measurable (bone) disease: The appearance of two or more new areas of uptake on bone scan (or NaF PET/CT) consistent with metastatic disease compared to previous imaging during castration therapy; the increased uptake of pre-existing lesions on bone scan will not be taken to constitute progression, and ambiguous results must be confirmed by other imaging modalities (e.g. X-ray, CT or MRI); clinical decisions about response or progression will be based on CT and bone scans

  • Patients may or may not have been treated previously with a nonsteroidal antiandrogen, such as flutamide, bicalutamide or nilutamide; for patients previously treated with an antiandrogen, they must be off treatment for at least 4 weeks (for flutamide) or 6 weeks (for bicalutamide or nilutamide) prior to registration and must have shown PSA progression after discontinuing the anti-androgen

  • Patients must have an Eastern Cooperative Oncology Group (ECOG) performance status of 0, 1, or 2

  • Absolute neutrophil count (ANC) >= 1500/mm^3 (=< 4 weeks prior to randomization)

  • Hemoglobin (HgB) >= 9.0 gr/dL (=< 4 weeks prior to randomization)

  • Platelets >= 100,000/mm^3 (=< 4 weeks prior to randomization)

  • Creatinine < 2.0 mg/dL (=< 4 weeks prior to randomization)

  • Patients must be informed of the experimental nature of the study and its potential risks, and must sign an Institutional Review Board (IRB)-approved written informed consent form indicating such an understanding

  • Patients with resected or irradiated brain metastases or those treated with stereotactic radiation therapy are eligible to enroll, provided that they do not require treatment with steroids that exceeds 10 mg of prednisone daily or equivalent

  • Sexually active males must use an accepted and effective method of double barrier contraception (vasectomy must be combined with a physical barrier method) or abstain from sexual intercourse for the duration of their participation in the study and for 26 weeks after the last dose of study drug

  • Any prior chemotherapy or androgen receptor (AR)-directed therapy for CRPC, (e.g. docetaxel, cabazitaxel, mitoxantrone, abiraterone acetate, ketoconazole, or enzalutamide); previous treatment with radium-223 or sipuleucel-T, or other immunotherapy-based treatment is allowed

  • Pure small cell or other variant (non-adenocarcinoma) prostate cancer histology for which treatment with abiraterone would not be considered appropriate

  • Patients may not be receiving other therapeutic investigational agents or be receiving concurrent anticancer therapy other than standard androgen deprivation therapy; concurrent treatment with agents to prevent skeletal-related events (such as zoledronic acid or denosumab) will be allowed as long as it was initiated prior to study registration or there are plans to initiate it after cycle 2 day 1

  • Any medical condition for which prednisone (corticosteroid) is contraindicated

  • If total bilirubin is > upper limit of normal (ULN) (NOTE: in subjects with Gilbertโ€™s syndrome, if total bilirubin is > ULN, measure direct and indirect bilirubin and if direct bilirubin is within normal range, subject may be eligible) or

  • Alanine (ALT) or aspartate (AST) aminotransferase > 1.5 x ULN

  • Active infection requiring treatment with antibiotics

  • History of adrenal insufficiency or hypoaldosteronism

  • Myocardial infarction or arterial thrombotic event =< 6 months of randomization, heart failure of New York Heart Association class II or higher, uncontrolled angina, severe uncontrolled ventricular arrhythmia

  • External beam radiation therapy =< 2 weeks of registration

  • Prior history of allergic reactions to granulocyte colony-stimulating factor (G-CSF)

  • Prior history of allergic reactions to docetaxel and/or to medications formulated with polysorbate 80

  • History of active malignancy; patients with a history of cancer that has been adequately treated and are free of disease recurrence for 3 years or more are allowed to participate; patients with non-melanoma skin cancers or carcinoma in situ of the bladder that have been adequately excised are eligible to participate

  • Life expectancy of < 12 months at screening

  • Grade >= 2 neuropathy

  • Uncontrolled hypertension (systolic BP >= 160 mmHg or diastolic blood pressure [BP] >= 100 mmHg). Patients with a history of hypertension are allowed to enroll provided blood pressure is controlled with anti-hypertensive treatment

  • NaF PET/CT OPTIONAL SUB-STUDY ELIGIBILITY CRITERIA

  • Ability to lie still for imaging

  • Weight =< 300 lbs (pounds)

  • Metastatic disease confined predominantly to the bones

United States
AK
Fairbanks
Fairbanks Memorial Hospital
Status: CLOSED_TO_ACCRUAL
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Email: Veronica.Stevenson@foundationhealth.org

AR
Ft. Smith
Mercy Hospital Fort Smith
Status: CLOSED_TO_ACCRUAL
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Hot Springs
CHI Saint Vincent Cancer Center Hot Springs
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: clinicaltrials@sfmc-gi.org

Jonesboro
NEA Baptist Memorial Hospital and Fowler Family Cancer Center - Jonesboro
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: Emily.Carvell@bmhcc.org

Little Rock
John L McClellan Memorial Veterans Hospital
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Email: richard.dennis2@va.gov

AZ
Goodyear
CTCA at Western Regional Medical Center
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Kingman
Kingman Regional Medical Center
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Email: ecog.rss@jimmy.harvard.edu

Phoenix
Cancer Center at Saint Joseph's
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CA
Antioch
Kaiser Permanente-Deer Valley Medical Center
Status: CLOSED_TO_ACCRUAL
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Email: Kpoct@kp.org

Arroyo Grande
Mission Hope Medical Oncology - Arroyo Grande
Status: CLOSED_TO_ACCRUAL
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Email: research@dignityhealth.org

PCR Oncology
Status: CLOSED_TO_ACCRUAL
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Email: research@sncrf.org

Auburn
Sutter Auburn Faith Hospital
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: bernicl@sutterhealth.org

Sutter Cancer Centers Radiation Oncology Services-Auburn
Status: CLOSED_TO_ACCRUAL
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Berkeley
Alta Bates Summit Medical Center-Herrick Campus
Status: CLOSED_TO_ACCRUAL
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Burlingame
Mills-Peninsula Medical Center
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Cameron Park
Sutter Cancer Centers Radiation Oncology Services-Cameron Park
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Castro Valley
Eden Hospital Medical Center
Status: CLOSED_TO_ACCRUAL
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Chico
Adventist Health Cancer Care Center Chico
Status: CLOSED_TO_ACCRUAL
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Email: hs-ccnctrials@ucdavis.edu

Davis
Sutter Davis Hospital
Status: CLOSED_TO_ACCRUAL
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Dublin
Epic Care-Dublin
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Kaiser Permanente Dublin
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Emeryville
Bay Area Breast Surgeons Inc
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Epic Care Partners in Cancer Care
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Fremont
Kaiser Permanente-Fremont
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Email: Kpoct@kp.org

Palo Alto Medical Foundation-Fremont
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Email: bernicl@sutterhealth.org

Fresno
Fresno Cancer Center
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Email: Kpoct@kp.org

Kaiser Permanente-Fresno
Status: CLOSED_TO_ACCRUAL
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Martinez
Contra Costa Regional Medical Center
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Modesto
Kaiser Permanente-Modesto
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Email: Kpoct@kp.org

Memorial Medical Center
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Mountain View
Palo Alto Medical Foundation-Camino Division
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Palo Alto Medical Foundation-Gynecologic Oncology
Status: CLOSED_TO_ACCRUAL
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Email: bernicl@sutterhealth.org

Novato
Sutter Cancer Research Consortium
Status: CLOSED_TO_ACCRUAL
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Email: bernicl@sutterhealth.org

Oakland
Alta Bates Summit Medical Center - Summit Campus
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Bay Area Tumor Institute
Status: CLOSED_TO_ACCRUAL
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Email: lradke@bati.org

Kaiser Permanente Oakland-Broadway
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Kaiser Permanente-Oakland
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Palo Alto
Palo Alto Medical Foundation Health Care
Status: CLOSED_TO_ACCRUAL
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Email: bernicl@sutterhealth.org

VA Palo Alto Health Care System
Status: CLOSED_TO_ACCRUAL
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Rancho Cordova
Kaiser Permanente-Rancho Cordova Cancer Center
Status: CLOSED_TO_ACCRUAL
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Email: Kpoct@kp.org

Redwood City
Kaiser Permanente-Redwood City
Status: CLOSED_TO_ACCRUAL
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Email: Kpoct@kp.org

Richmond
Kaiser Permanente-Richmond
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: Kpoct@kp.org

Rohnert Park
Rohnert Park Cancer Center
Status: CLOSED_TO_ACCRUAL
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Email: Kpoct@kp.org

Roseville
Kaiser Permanente-Roseville
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: Kpoct@kp.org

Sutter Cancer Centers Radiation Oncology Services-Roseville
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: bernicl@sutterhealth.org

Sutter Roseville Medical Center
Status: CLOSED_TO_ACCRUAL
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Email: bernicl@sutterhealth.org

The Permanente Medical Group-Roseville Radiation Oncology
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: Kpoct@kp.org

Sacramento
Kaiser Permanente - Sacramento
Status: CLOSED_TO_ACCRUAL
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Email: Kpoct@kp.org

Kaiser Permanente Downtown Commons
Status: CLOSED_TO_ACCRUAL
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Email: kpoct@kp.org

Kaiser Permanente-South Sacramento
Status: CLOSED_TO_ACCRUAL
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Email: Kpoct@kp.org

South Sacramento Cancer Center
Status: CLOSED_TO_ACCRUAL
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Email: Kpoct@kp.org

Sutter Medical Center Sacramento
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: bernicl@sutterhealth.org

San Francisco
California Pacific Medical Center-Pacific Campus
Status: CLOSED_TO_ACCRUAL
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Email: bernicl@sutterhealth.org

Kaiser Permanente-San Francisco
Status: CLOSED_TO_ACCRUAL
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Email: Kpoct@kp.org

San Jose
Kaiser Permanente-Santa Teresa-San Jose
Status: CLOSED_TO_ACCRUAL
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Email: Kpoct@kp.org

San Leandro
Kaiser Permanente San Leandro
Status: CLOSED_TO_ACCRUAL
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Email: Kpoct@kp.org

San Luis Obispo
Pacific Central Coast Health Center-San Luis Obispo
Status: CLOSED_TO_ACCRUAL
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Email: Diane.DeVos-Schmidt@DignityHealth.org

San Mateo
Mills Health Center
Status: CLOSED_TO_ACCRUAL
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Email: ctsucontact@westat.com

San Rafael
Kaiser Permanente-San Rafael
Status: CLOSED_TO_ACCRUAL
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Email: Kpoct@kp.org

Kaiser San Rafael-Gallinas
Status: CLOSED_TO_ACCRUAL
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Email: Kpoct@kp.org

Santa Clara
Kaiser Permanente Medical Center - Santa Clara
Status: CLOSED_TO_ACCRUAL
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Email: Kpoct@kp.org

Santa Cruz
Palo Alto Medical Foundation-Santa Cruz
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: bernicl@sutterhealth.org

Santa Maria
Mission Hope Medical Oncology - Santa Maria
Status: CLOSED_TO_ACCRUAL
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Email: research@dignityhealth.org

Santa Rosa
Kaiser Permanente-Santa Rosa
Status: CLOSED_TO_ACCRUAL
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Email: Kpoct@kp.org

Sutter Pacific Medical Foundation
Status: CLOSED_TO_ACCRUAL
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Email: bernicl@sutterhealth.org

South San Francisco
Kaiser Permanente Cancer Treatment Center
Status: CLOSED_TO_ACCRUAL
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Email: Kpoct@kp.org

Kaiser Permanente-South San Francisco
Status: CLOSED_TO_ACCRUAL
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Email: Kpoct@kp.org

Stockton
Kaiser Permanente-Stockton
Status: CLOSED_TO_ACCRUAL
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Email: Kpoct@kp.org

Sunnyvale
Palo Alto Medical Foundation-Sunnyvale
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: bernicl@sutterhealth.org

Vacaville
Kaiser Permanente Medical Center-Vacaville
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: Kpoct@kp.org

Sutter Cancer Centers Radiation Oncology Services-Vacaville
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: bernicl@sutterhealth.org

Vallejo
Kaiser Permanente-Vallejo
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: Kpoct@kp.org

Sutter Solano Medical Center / Cancer Center
Status: CLOSED_TO_ACCRUAL
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Email: bernicl@sutterhealth.org

Walnut Creek
Epic Care Cyberknife Center
Status: CLOSED_TO_ACCRUAL
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Email: somega@bati.org

Kaiser Permanente-Walnut Creek
Status: CLOSED_TO_ACCRUAL
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Email: Kpoct@kp.org

CO
Aurora
Rocky Mountain Cancer Centers-Aurora
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: info@westernstatesncorp.org

The Medical Center of Aurora
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: info@westernstatesncorp.org

Boulder
Boulder Community Foothills Hospital
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: info@westernstatesncorp.org

Boulder Community Hospital
Status: ACTIVE
Contact: Site Public Contact
Email: jbloomfield@co-cancerresearch.org

Rocky Mountain Cancer Centers-Boulder
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: info@westernstatesncorp.org

Centennial
Rocky Mountain Cancer Centers - Centennial
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: info@westernstatesncorp.org

Colorado Springs
Penrose-Saint Francis Healthcare
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: clinicaltrials@sfmc-gi.org

Rocky Mountain Cancer Centers-Penrose
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: info@westernstatesncorp.org

Denver
Cancer Center of Colorado at Sloan's Lake
Status: CLOSED_TO_ACCRUAL
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Colorado Blood Cancer Institute
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: info@westernstatesncorp.org

Denver Health Medical Center
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: ccrp@co-cancerresearch.org

National Jewish Health-Main Campus
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: glicht@co-cancerresearch.org

Porter Adventist Hospital
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: clinicaltrials@sfmc-gi.org

Presbyterian - Saint Lukes Medical Center - Health One
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: info@westernstatesncorp.org

Rocky Mountain Cancer Centers-Midtown
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: info@westernstatesncorp.org

Rocky Mountain Cancer Centers-Rose
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: info@westernstatesncorp.org

Rose Medical Center
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: ccrp@co-cancerresearch.org

SCL Health Saint Joseph Hospital
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: info@westernstatesncorp.org

The Women's Imaging Center
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: info@westernstatesncorp.org

Western Surgical Care
Status: CLOSED_TO_ACCRUAL
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Durango
Mercy Medical Center
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: clinicaltrials@sfmc-gi.org

Southwest Oncology PC
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: clinicaltrials@sfmc-gi.org

Englewood
Mountain Blue Cancer Care Center - Swedish
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: info@westernstatesncorp.org

Swedish Medical Center
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: info@westernstatesncorp.org

Golden
Mountain Blue Cancer Care Center
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: clinicaltrials@sfmc-gi.org

National Jewish Health-Western Hematology Oncology
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: glicht@co-cancerresearch.org

Grand Junction
Grand Valley Oncology
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: gvoclinicaltrials@gjhosp.org

Saint Mary's Hospital and Regional Medical Center
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: ccrp@co-cancerresearch.org

Greeley
North Colorado Medical Center
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: info@westernstatesncorp.org

Lafayette
Good Samaritan Medical Center
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact

Lakewood
Rocky Mountain Cancer Centers-Lakewood
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: info@westernstatesncorp.org

Saint Anthony Hospital
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: clinicaltrials@sfmc-gi.org

Littleton
Littleton Adventist Hospital
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: clinicaltrials@sfmc-gi.org

Rocky Mountain Cancer Centers-Littleton
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: info@westernstatesncorp.org

Lone Tree
Rocky Mountain Cancer Centers-Sky Ridge
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: info@westernstatesncorp.org

Sky Ridge Medical Center
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: info@westernstatesncorp.org

Longmont
Longmont United Hospital
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: clinicaltrials@sfmc-gi.org

Rocky Mountain Cancer Centers-Longmont
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: info@westernstatesncorp.org

Loveland
McKee Medical Center
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: info@westernstatesncorp.org

Parker
Parker Adventist Hospital
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: clinicaltrials@sfmc-gi.org

Rocky Mountain Cancer Centers-Parker
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: info@westernstatesncorp.org

Pueblo
Rocky Mountain Cancer Centers - Pueblo
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: info@westernstatesncorp.org

Saint Mary Corwin Medical Center
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: clinicaltrials@sfmc-gi.org

Thornton
National Jewish Health-Northern Hematology Oncology
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: glicht@co-cancerresearch.org

Rocky Mountain Cancer Centers-Thornton
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: info@westernstatesncorp.org

Wheat Ridge
SCL Health Lutheran Medical Center
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: ccrp@co-cancerresearch.org

CT
Derby
Smilow Cancer Hospital-Derby Care Center
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: canceranswers@yale.edu

Fairfield
Smilow Cancer Hospital Care Center-Fairfield
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: canceranswers@yale.edu

Greenwich
Greenwich Hospital
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact

Guilford
Smilow Cancer Hospital Care Center - Guiford
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: canceranswers@yale.edu

Hartford
Smilow Cancer Hospital Care Center at Saint Francis
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: canceranswers@yale.edu

Middletown
Middlesex Hospital
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: beth_slifer@midhosp.org

New Haven
Smilow Cancer Center / Yale-New Haven Hospital
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: canceranswers@yale.edu

Yale University
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: canceranswers@yale.edu

North Haven
Yale-New Haven Hospital North Haven Medical Center
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: canceranswers@yale.edu

Trumbull
Smilow Cancer Hospital Care Center-Trumbull
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: canceranswers@yale.edu

Waterbury
Smilow Cancer Hospital-Waterbury Care Center
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: canceranswers@yale.edu

Waterford
Smilow Cancer Hospital Care Center - Waterford
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: canceranswers@yale.edu

DC
Washington
George Washington University Medical Center
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact

MedStar Georgetown University Hospital
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact

Sibley Memorial Hospital
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: jquiver1@jhmi.edu

DE
Dover
Bayhealth Hospital Kent Campus
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: mary_ella_quillen@bayhealth.org

Frankford
Beebe South Coastal Health Campus
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: Dmiskin@Beebehealthcare.org

Lewes
Beebe Medical Center
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: Dmiskin@Beebehealthcare.org

Milford
Bayhealth Hospital Sussex Campus
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: jenni_glick@bayhealth.org

Newark
Christiana Care Health System-Christiana Hospital
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: mhayden@christianacare.org

Delaware Clinical and Laboratory Physicians PA
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: mhayden@christianacare.org

Helen F Graham Cancer Center
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: mhayden@christianacare.org

Medical Oncology Hematology Consultants PA
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: mhayden@christianacare.org

Rehoboth Beach
Beebe Health Campus
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: Dmiskin@Beebehealthcare.org

Seaford
TidalHealth Nanticoke / Allen Cancer Center
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: anna-maria.howard@peninsula.org

Wilmington
Christiana Care Health System-Wilmington Hospital
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: mhayden@christianacare.org

GA
Atlanta
Emory Saint Joseph's Hospital
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact

Emory University Hospital / Winship Cancer Institute
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact

Emory University Hospital Midtown
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact

Grady Health System
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact

Columbus
John B Amos Cancer Center
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: cdean@iacthealth.com

Decatur
Atlanta VA Medical Center
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact

Newnan
CTCA at Southeastern Regional Medical Center
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact

HI
Aiea
Hawaii Cancer Care - Savio
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact

Pali Momi Medical Center
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact

Queen's Cancer Center - Pearlridge
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact

The Cancer Center of Hawaii-Pali Momi
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact

Honolulu
Hawaii Cancer Care Inc - Waterfront Plaza
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: i.webster@hawaiicancercare.com

Hawaii Cancer Care Inc-Liliha
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact

Island Urology
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: virginia@cc.hawaii.edu

Kaiser Permanente Moanalua Medical Center
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: shelley.a.clark@kp.org

Kapiolani Medical Center for Women and Children
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact

Kuakini Medical Center
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact

Queen's Cancer Cenrer - POB I
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact

Queen's Cancer Center - Kuakini
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact

Queen's Medical Center
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact

Straub Clinic and Hospital
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact

The Cancer Center of Hawaii-Liliha
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact

University of Hawaii Cancer Center
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact

Lihue
Wilcox Memorial Hospital and Kauai Medical Clinic
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact

IA
Ames
Mary Greeley Medical Center
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact

McFarland Clinic PC - Ames
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: ksoder@mcfarlandclinic.com

Boone
McFarland Clinic PC-Boone
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact

Clive
Medical Oncology and Hematology Associates-West Des Moines
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: clinicaltrials@sfmc-gi.org

Mercy Cancer Center-West Lakes
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: clinicaltrials@sfmc-gi.org

Council Bluffs
Alegent Health Mercy Hospital
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: clinicaltrials@sfmc-gi.org

Creston
Greater Regional Medical Center
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: clinicaltrials@sfmc-gi.org

Des Moines
Broadlawns Medical Center
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact

Iowa Lutheran Hospital
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact

Iowa Methodist Medical Center
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact

Medical Oncology and Hematology Associates-Des Moines
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact

Mercy Medical Center - Des Moines
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: clinicaltrials@sfmc-gi.org

Mission Cancer and Blood - Laurel
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: clinicaltrials@sfmc-gi.org

Fort Dodge
McFarland Clinic PC-Trinity Cancer Center
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact

Trinity Regional Medical Center
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact

Iowa City
University of Iowa / Holden Comprehensive Cancer Center
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact

Jefferson
McFarland Clinic PC-Jefferson
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact

Marshalltown
McFarland Clinic PC-Marshalltown
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact

West Des Moines
Mercy Medical Center-West Lakes
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: clinicaltrials@sfmc-gi.org

Methodist West Hospital
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact

ID
Boise
Saint Alphonsus Cancer Care Center-Boise
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: stephanie.couch@stjoeshealth.org

Caldwell
Saint Alphonsus Cancer Care Center-Caldwell
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: stephanie.couch@stjoeshealth.org

Coeur D'Alene
Kootenai Health - Coeur d'Alene
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: mccinfo@mtcancer.org

Emmett
Walter Knox Memorial Hospital
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: stephanie.couch@stjoeshealth.org

Meridian
Idaho Urologic Institute-Meridian
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: stephanie.couch@stjoeshealth.org

Nampa
Saint Alphonsus Medical Center-Nampa
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: stephanie.couch@stjoeshealth.org

Post Falls
Kootenai Clinic Cancer Services - Post Falls
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: mccinfo@mtcancer.org

Sandpoint
Kootenai Cancer Clinic
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: mccinfo@mtcancer.org

IL
Aurora
Rush - Copley Medical Center
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: Cancer.Research@rushcopley.com

Bloomington
Illinois CancerCare-Bloomington
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: andersonj@illinoiscancercare.com

Canton
Illinois CancerCare-Canton
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: andersonj@illinoiscancercare.com

Carbondale
Memorial Hospital of Carbondale
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: clinical.research@sih.net

Carterville
SIH Cancer Institute
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: clinical.research@sih.net

Carthage
Illinois CancerCare-Carthage
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: andersonj@illinoiscancercare.com

Centralia
Centralia Oncology Clinic
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: rhamrick@dmhhs.org

Chicago
Northwestern University
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: cancer@northwestern.edu

Danville
Carle on Vermilion
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: Research@carle.com

DeKalb
Northwestern Medicine Cancer Center Kishwaukee
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: Donald.Smith3@nm.org

Decatur
Cancer Care Specialists of Illinois - Decatur
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: rhamrick@dmhhs.org

Decatur Memorial Hospital
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: rhamrick@dmhhs.org

Dixon
Illinois CancerCare-Dixon
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact

Effingham
Carle Physician Group-Effingham
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: Research@carle.com

Crossroads Cancer Center
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: rhamrick@dmhhs.org

Eureka
Illinois CancerCare-Eureka
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: andersonj@illinoiscancercare.com

Evanston
NorthShore University HealthSystem-Evanston Hospital
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact

Galesburg
Illinois CancerCare-Galesburg
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: andersonj@illinoiscancercare.com

Western Illinois Cancer Treatment Center
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact

Geneva
Northwestern Medicine Cancer Center Delnor
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: Donald.Smith3@nm.org

Glenview
NorthShore University HealthSystem-Glenbrook Hospital
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact

Harvey
Ingalls Memorial Hospital
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: clinicaltrials@ingalls.org

Highland Park
NorthShore University HealthSystem-Highland Park Hospital
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact

Joliet
Duly Health and Care Joliet
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: maureenc@jolietoncology.com

Kewanee
Illinois CancerCare-Kewanee Clinic
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: andersonj@illinoiscancercare.com

Lake Forest
Northwestern Medicine Lake Forest Hospital
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: cancertrials@northwestern.edu

Macomb
Illinois CancerCare-Macomb
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: andersonj@illinoiscancercare.com

Mattoon
Carle Physician Group-Mattoon / Charleston
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: Research@carle.com

Mount Vernon
Good Samaritan Regional Health Center
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact

O'Fallon
Cancer Care Center of O'Fallon
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: morganthaler.jodi@mhsil.com

Ottawa
Illinois CancerCare-Ottawa Clinic
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: andersonj@illinoiscancercare.com

Pekin
Illinois CancerCare-Pekin
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: andersonj@illinoiscancercare.com

Peoria
Illinois CancerCare-Peoria
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: andersonj@illinoiscancercare.com

Methodist Medical Center of Illinois
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: andersonj@illinoiscancercare.com

Peru
Illinois CancerCare-Peru
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: andersonj@illinoiscancercare.com

Valley Radiation Oncology
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact

Princeton
Illinois CancerCare-Princeton
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: andersonj@illinoiscancercare.com

Skokie
North Shore Medical Center
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: ecog.rss@jimmy.harvard.edu

Springfield
Memorial Medical Center
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact

Southern Illinois University School of Medicine
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact

Springfield Clinic
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact

Swansea
Southwest Illinois Health Services LLP
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: lynns@thecancercenter.com

Urbana
Carle Cancer Center
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: Research@carle.com

The Carle Foundation Hospital
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: Research@carle.com

Warrenville
Northwestern Medicine Cancer Center Warrenville
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: Donald.Smith3@nm.org

Yorkville
Rush-Copley Healthcare Center
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: Cancer.Research@rushcopley.com

IN
Evansville
Deaconess Clinic Downtown
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: Research@Deaconess.com

Fort Wayne
Parkview Hospital Randallia
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: parkviewresearch@parkview.com

Parkview Regional Medical Center
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact

Indianapolis
Indiana University / Melvin and Bren Simon Cancer Center
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: iutrials@iu.edu

Richard L. Roudebush Veterans Affairs Medical Center
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: iutrials@iu.edu

Sidney and Lois Eskenazi Hospital
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: iutrials@iu.edu

Mishawaka
Memorial Regional Cancer Center Day Road
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: ctsucontact@westat.com

Newburgh
Chancellor Center for Oncology
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: Research@Deaconess.com

Richmond
Reid Health
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: clinical.trials@daytonncorp.org

South Bend
Memorial Hospital of South Bend
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact

KS
Coffeyville
Coffeyville Regional Medical Center
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact

Fairway
University of Kansas Clinical Research Center
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: KUCC_Navigation@kumc.edu

Garden City
Central Care Cancer Center - Garden City
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: aroland@kccop.org

Great Bend
Central Care Cancer Center - Great Bend
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: aroland@kccop.org

Hays
HaysMed University of Kansas Health System
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact

Kansas City
University of Kansas Cancer Center
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: KUCC_Navigation@kumc.edu

University of Kansas Cancer Center-West
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: KUCC_Navigation@kumc.edu

Lawrence
Lawrence Memorial Hospital
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: Stephanie.Norris@LMH.ORG

Lenexa
Kansas Institute of Medicine Cancer and Blood Center
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: aroland@kccop.org

Minimally Invasive Surgery Hospital
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: aroland@kccop.org

Olathe
Olathe Health Cancer Center
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: Jeni.wakefield@olathehealth.org

Overland Park
Menorah Medical Center
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: aroland@kccop.org

University of Kansas Cancer Center-Overland Park
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: KUCC_Navigation@kumc.edu

Pittsburg
Ascension Via Christi - Pittsburg
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: jennifer.jameson@ascension.org

Salina
Salina Regional Health Center
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: mleepers@srhc.com

Topeka
University of Kansas Health System Saint Francis Campus
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact

Westwood
University of Kansas Hospital-Westwood Cancer Center
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: KUCC_Navigation@kumc.edu

Wichita
Cancer Center of Kansas - Wichita
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: Keisha.humphries@ascension.org

Cancer Center of Kansas-Wichita Medical Arts Tower
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: Keisha.humphries@ascension.org

KY
Bardstown
Flaget Memorial Hospital
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: clinicaltrials@sfmc-gi.org

Corbin
Commonwealth Cancer Center-Corbin
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: clinicaltrials@sfmc-gi.org

Lexington
Saint Joseph Hospital East
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: clinicaltrials@sfmc-gi.org

Saint Joseph Radiation Oncology Resource Center
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: clinicaltrials@sfmc-gi.org

University of Kentucky / Markey Cancer Center
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact

London
Saint Joseph London
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: clinicaltrials@sfmc-gi.org

Louisville
Jewish Hospital
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: clinicaltrials@sfmc-gi.org

Saints Mary and Elizabeth Hospital
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: clinicaltrials@sfmc-gi.org

UofL Health Medical Center Northeast
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: clinicaltrials@sfmc-gi.org

Shepherdsville
Jewish Hospital Medical Center South
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: clinicaltrials@sfmc-gi.org

LA
Metairie
East Jefferson General Hospital
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: emede1@lsuhsc.edu

LSU Healthcare Network / Metairie Multi-Specialty Clinic
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: emede1@lsuhsc.edu

New Orleans
Louisiana State University Health Science Center
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: emede1@lsuhsc.edu

University Medical Center New Orleans
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: emede1@lsuhsc.edu

Veteran's Administration Medical Center - New Orleans
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: emede1@lsuhsc.edu

MA
Fitchburg
Simonds-Sinon Regional Cancer Center
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact

Springfield
Baystate Medical Center
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: tamara.wrenn@baystatehealth.org

Worcester
UMass Memorial Medical Center - University Campus
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: cancer.research@umassmed.edu

MD
Annapolis
Anne Arundel Medical Center
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: research@aahs.org

Baltimore
Johns Hopkins University / Sidney Kimmel Cancer Center
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: jhcccro@jhmi.edu

Bethesda
Walter Reed National Military Medical Center
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact

ME
Augusta
Harold Alfond Center for Cancer Care
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact

Belfast
Waldo County General Hospital
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact

Biddeford
MaineHealth / SMHC Cancer Care and Blood Disorders-Biddeford
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: LLemire@mmc.org

Norway
Stephens Memorial Hospital
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: OncClinicalResearch@mmc.org

Rockport
Penobscot Bay Medical Center
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: ClinicalResearch@mmc.org

Sanford
MaineHealth / SMHC Cancer Care and Blood Disorders-Sanford
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: LLemire@mmc.org

South Portland
Maine Medical Partners - South Portland
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: ClinicalResearch@mmc.org

MI
Adrian
Hickman Cancer Center
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact

Battle Creek
Bronson Battle Creek
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: crcwm-regulatory@crcwm.org

Bay City
McLaren Cancer Institute-Bay City
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: ctoadmin@karmanos.org

Bloomfield
McLaren Cancer Institute-Bloomfield
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: ctoadmin@karmanos.org

Clarkston
McLaren Cancer Institute-Clarkston
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: ctoadmin@karmanos.org

Detroit
Wayne State University / Karmanos Cancer Institute
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: ctoadmin@karmanos.org

Farmington Hills
Weisberg Cancer Treatment Center
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: ctoadmin@karmanos.org

Flint
McLaren Cancer Institute-Flint
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: ctoadmin@karmanos.org

Singh and Arora Hematology Oncology PC
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: ctoadmin@karmanos.org

Grand Rapids
Helen DeVos Children's Hospital at Spectrum Health
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: crcwm-regulatory@crcwm.org

Mercy Health Saint Mary's
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: crcwm-regulatory@crcwm.org

Spectrum Health at Butterworth Campus
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: crcwm-regulatory@crcwm.org

Kalamazoo
Borgess Medical Center
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: crcwm-regulatory@crcwm.org

Bronson Methodist Hospital
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: crcwm-regulatory@crcwm.org

West Michigan Cancer Center
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: crcwm-regulatory@crcwm.org

Lansing
Karmanos Cancer Institute at McLaren Greater Lansing
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: ctoadmin@karmanos.org

Lapeer
McLaren Cancer Institute-Lapeer Region
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: ctoadmin@karmanos.org

Monroe
Toledo Clinic Cancer Centers-Monroe
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact

Mount Clemens
McLaren Cancer Institute-Macomb
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: ctoadmin@karmanos.org

Muskegon
Mercy Health Mercy Campus
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: crcwm-regulatory@crcwm.org

Niles
Lakeland Hospital Niles
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact

Norton Shores
Cancer and Hematology Centers of Western Michigan - Norton Shores
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: connie.szczepanek@crcwm.org

Petoskey
McLaren Cancer Institute-Northern Michigan
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: ctoadmin@karmanos.org

Port Huron
Huron Medical Center PC
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: research@sncrf.org

Lake Huron Medical Center
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: research@sncrf.org

Reed City
Spectrum Health Reed City Hospital
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: crcwm-regulatory@crcwm.org

Saint Joseph
Lakeland Medical Center Saint Joseph
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: crcwm-regulatory@crcwm.org

Marie Yeager Cancer Center
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: crcwm-regulatory@crcwm.org

Traverse City
Munson Medical Center
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: crcwm-regulatory@crcwm.org

Wyoming
Metro Health Hospital
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: crcwm-regulatory@crcwm.org

MN
Aitkin
Riverwood Healthcare Center
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: CancerTrials@EssentiaHealth.org

Bemidji
Sanford Joe Lueken Cancer Center
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: OncologyClinicalTrialsFargo@sanfordhealth.org

Brainerd
Essentia Health Saint Joseph's Medical Center
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: CancerTrials@EssentiaHealth.org

Burnsville
Fairview Ridges Hospital
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: mmcorc@healthpartners.com

Minnesota Oncology - Burnsville
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: mmcorc@healthpartners.com

Cambridge
Cambridge Medical Center
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: mmcorc@healthpartners.com

Coon Rapids
Mercy Hospital
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: mmcorc@healthpartners.com

Deer River
Essentia Health - Deer River Clinic
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: CancerTrials@EssentiaHealth.org

Detroit Lakes
Essentia Health Saint Mary's - Detroit Lakes Clinic
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: CancerTrials@EssentiaHealth.org

Duluth
Essentia Health Cancer Center
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: CancerTrials@EssentiaHealth.org

Essentia Health Saint Mary's Medical Center
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: CancerTrials@EssentiaHealth.org

Miller-Dwan Hospital
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: CancerTrials@EssentiaHealth.org

Edina
Fairview Southdale Hospital
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: mmcorc@healthpartners.com

Fergus Falls
Lake Region Healthcare Corporation-Cancer Care
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: CancerTrials@EssentiaHealth.org

Fosston
Essentia Health - Fosston
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: CancerTrials@EssentiaHealth.org

Fridley
Unity Hospital
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: mmcorc@healthpartners.com

Hibbing
Essentia Health Hibbing Clinic
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact

Maple Grove
Fairview Clinics and Surgery Center Maple Grove
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: mmcorc@healthpartners.com

Maplewood
Minnesota Oncology Hematology PA-Maplewood
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: mmcorc@healthpartners.com

Saint John's Hospital - Healtheast
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: mmcorc@healthpartners.com

Minneapolis
Abbott-Northwestern Hospital
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: mmcorc@healthpartners.com

Health Partners Inc
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: mmcorc@healthpartners.com

Hennepin County Medical Center
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: mmcorc@healthpartners.com

Monticello
Monticello Cancer Center
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: mmcorc@healthpartners.com

New Ulm
New Ulm Medical Center
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: mmcorc@healthpartners.com

Park Rapids
Essentia Health - Park Rapids
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: CancerTrials@EssentiaHealth.org

Princeton
Fairview Northland Medical Center
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: mmcorc@healthpartners.com

Robbinsdale
North Memorial Medical Health Center
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: mmcorc@healthpartners.com

Saint Cloud
Coborn Cancer Center at Saint Cloud Hospital
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: coborncancercenter@centracare.com

Saint Louis Park
Park Nicollet Clinic - Saint Louis Park
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: mmcorc@healthpartners.com

Saint Paul
Regions Hospital
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: mmcorc@healthpartners.com

United Hospital
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: mmcorc@healthpartners.com

Sandstone
Essentia Health Sandstone
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: CancerTrials@EssentiaHealth.org

Shakopee
Saint Francis Regional Medical Center
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: mmcorc@healthpartners.com

Stillwater
Lakeview Hospital
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: mmcorc@healthpartners.com

Thief River Falls
Sanford Thief River Falls Medical Center
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact

Virginia
Essentia Health Virginia Clinic
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: CancerTrials@EssentiaHealth.org

Waconia
Ridgeview Medical Center
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: mmcorc@healthpartners.com

Willmar
Rice Memorial Hospital
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: mmcorc@healthpartners.com

Woodbury
Minnesota Oncology Hematology PA-Woodbury
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: mmcorc@healthpartners.com

Worthington
Sanford Cancer Center Worthington
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact

Wyoming
Fairview Lakes Medical Center
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: mmcorc@healthpartners.com

MO
Ballwin
Saint Louis Cancer and Breast Institute-Ballwin
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact

Bolivar
Central Care Cancer Center - Bolivar
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: aroland@kccop.org

Bonne Terre
Parkland Health Center-Bonne Terre
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact

Branson
Cox Cancer Center Branson
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact

Cape Girardeau
Saint Francis Medical Center
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: sfmc@sfmc.net

Southeast Cancer Center
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact

Columbia
University of Missouri - Ellis Fischel
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact

Creve Coeur
Siteman Cancer Center at West County Hospital
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: info@siteman.wustl.edu

Farmington
Parkland Health Center - Farmington
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact

Independence
Centerpoint Medical Center LLC
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: aroland@kccop.org

Jefferson City
Capital Region Southwest Campus
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: swooden@mail.crmc.org

Joplin
Freeman Health System
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: LJCrockett@freemanhealth.com

Mercy Hospital Joplin
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: esmeralda.carrillo@mercy.net

Kansas City
Research Medical Center
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: aroland@kccop.org

The University of Kansas Cancer Center-South
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: ctnursenav@kumc.edu

Truman Medical Centers
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact

University of Kansas Cancer Center - North
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: KUCC_Navigation@kumc.edu

Lee's Summit
University of Kansas Cancer Center - Lee's Summit
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: KUCC_Navigation@kumc.edu

Rolla
Delbert Day Cancer Institute at PCRMC
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: kaysmith@phelpshealth.org

Mercy Clinic-Rolla-Cancer and Hematology
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact

Saint Joseph
Heartland Regional Medical Center
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: linda.schumacher@mymlc.com

Saint Louis
Mercy Hospital Saint Louis
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact

Mercy Hospital South
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: janet.lesko@mercy.net

Missouri Baptist Medical Center
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact

Saint Louis Cancer and Breast Institute-South City
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact

Siteman Cancer Center at Christian Hospital
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: info@siteman.wustl.edu

Siteman Cancer Center-South County
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: info@siteman.wustl.edu

Veteran's Affairs Medical Center - Saint Louis
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: ctsucontact@westat.com

Washington University School of Medicine
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: info@siteman.wustl.edu

Saint Peters
Siteman Cancer Center at Saint Peters Hospital
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: info@siteman.wustl.edu

Sainte Genevieve
Sainte Genevieve County Memorial Hospital
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact

Springfield
CoxHealth South Hospital
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact

Mercy Hospital Springfield
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact

Sullivan
Missouri Baptist Sullivan Hospital
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact

Sunset Hills
Missouri Baptist Outpatient Center-Sunset Hills
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact

Washington
Mercy Hospital Washington
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact

MS
Grenada
Baptist Cancer Center-Grenada
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: BCCclintrials@bmhcc.org

Jackson
University of Mississippi Medical Center
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact

New Albany
Baptist Memorial Hospital and Cancer Center-Union County
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: BCCclintrials@bmhcc.org

Oxford
Baptist Memorial Hospital and Cancer Center-Oxford
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: BCCclintrials@bmhcc.org

Southhaven
Baptist Memorial Hospital and Cancer Center-Desoto
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: BCCclintrials@bmhcc.org

MT
Anaconda
Community Hospital of Anaconda
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: mccinfo@mtcancer.org

Billings
Billings Clinic Cancer Center
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: research@billingsclinic.org

Saint Vincent Frontier Cancer Center
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact

Saint Vincent Healthcare
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: mccinfo@mtcancer.org

Bozeman
Bozeman Deaconess Hospital
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: mccinfo@mtcancer.org

Butte
Saint James Community Hospital and Cancer Treatment Center
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact

Great Falls
Benefis Healthcare- Sletten Cancer Institute
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: mccinfo@mtcancer.org

Great Falls Clinic
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: mccinfo@mtcancer.org

Helena
Saint Peter's Community Hospital
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: mccinfo@mtcancer.org

Kalispell
Kalispell Regional Medical Center
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: mccinfo@mtcancer.org

Missoula
Community Medical Hospital
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: mccinfo@mtcancer.org

NC
Clinton
Southeastern Medical Oncology Center-Clinton
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: jfields@cancersmoc.com

Goldsboro
Southeastern Medical Oncology Center-Goldsboro
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: jfields@cancersmoc.com

Wayne Memorial Hospital
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: ecooke@cancersmoc.com

Greenville
East Carolina University
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: eubankss@ecu.edu

Jacksonville
Onslow Memorial Hospital
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: ecooke@cancersmoc.com

Southeastern Medical Oncology Center-Jacksonville
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: jfields@cancersmoc.com

Kenansville
Vidant Oncology-Kenansville
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: Carla.Zimmerman@vidanthealth.com

Kinston
Vidant Oncology-Kinston
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: Carla.Zimmerman@vidanthealth.com

Richlands
Vidant Oncology-Richlands
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: Carla.Zimmerman@vidanthealth.com

Washington
Marion L Shepard Cancer Center at Vidant Beaufort Hospital
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact

ND
Bismarck
Sanford Bismarck Medical Center
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: OncologyClinicalTrialsFargo@sanfordhealth.org

Fargo
Essentia Health Cancer Center-South University Clinic
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: CancerTrials@EssentiaHealth.org

Sanford Broadway Medical Center
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: OncologyClinicalTrialsFargo@sanfordhealth.org

Sanford Roger Maris Cancer Center
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: OncologyClinicalTrialsFargo@sanfordhealth.org

Sanford South University Medical Center
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact

Jamestown
Essentia Health - Jamestown Clinic
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: CancerTrials@EssentiaHealth.org

NE
Grand Island
CHI Health Saint Francis
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: clinicaltrials@sfmc-gi.org

Kearney
CHI Health Good Samaritan
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: clinicaltrials@sfmc-gi.org

Heartland Hematology and Oncology
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: clinicaltrials@sfmc-gi.org

Lincoln
Saint Elizabeth Regional Medical Center
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: clinicaltrials@sfmc-gi.org

Omaha
Alegent Health Bergan Mercy Medical Center
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: clinicaltrials@sfmc-gi.org

Alegent Health Immanuel Medical Center
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: clinicaltrials@sfmc-gi.org

Alegent Health Lakeside Hospital
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: clinicaltrials@sfmc-gi.org

Creighton University Medical Center
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: clinicaltrials@sfmc-gi.org

Hematology and Oncology Consultants PC
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: clinicaltrials@sfmc-gi.org

Papillion
Midlands Community Hospital
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: clinicaltrials@sfmc-gi.org

NJ
Cape May Court House
AtlantiCare Health Park-Cape May Court House
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact

Egg Harbor Township
AtlantiCare Surgery Center
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact

Teaneck
Holy Name Hospital
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact

NV
Carson City
Carson Tahoe Regional Medical Center
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: research@sncrf.org

Henderson
Cancer and Blood Specialists-Henderson
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: research@sncrf.org

Comprehensive Cancer Centers of Nevada - Henderson
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: research@sncrf.org

Comprehensive Cancer Centers of Nevada-Horizon Ridge
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: research@sncrf.org

Comprehensive Cancer Centers of Nevada-Southeast Henderson
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: research@sncrf.org

GenesisCare USA - Henderson
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: research@sncrf.org

Las Vegas Cancer Center-Henderson
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: research@sncrf.org

Las Vegas Urology - Green Valley
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: research@sncrf.org

Las Vegas Urology - Pebble
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: research@sncrf.org

OptumCare Cancer Care at Seven Hills
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: research@sncrf.org

Urology Specialists of Nevada - Green Valley
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: research@sncrf.org

Las Vegas
Alliance for Childhood Diseases / Cure 4 the Kids Foundation
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: research@sncrf.org

Ann M Wierman MD LTD
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: research@sncrf.org

Cancer Therapy and Integrative Medicine
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: research@sncrf.org

Cancer and Blood Specialists-Shadow
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: research@sncrf.org

Cancer and Blood Specialists-Tenaya
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: research@sncrf.org

Comprehensive Cancer Centers of Nevada
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: research@sncrf.org

Comprehensive Cancer Centers of Nevada - Central Valley
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: research@sncrf.org

Comprehensive Cancer Centers of Nevada - Northwest
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: research@sncrf.org

Comprehensive Cancer Centers of Nevada - Town Center
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: research@sncrf.org

Comprehensive Cancer Centers of Nevada-Summerlin
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: research@sncrf.org

Desert West Surgery
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: research@sncrf.org

GenesisCare USA - Fort Apache
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: research@sncrf.org

GenesisCare USA - Las Vegas
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: research@sncrf.org

GenesisCare USA - Vegas Tenaya
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: research@sncrf.org

HealthCare Partners Medical Group Oncology / Hematology-Centennial Hills
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: research@sncrf.org

HealthCare Partners Medical Group Oncology / Hematology-Maryland Parkway
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: research@sncrf.org

HealthCare Partners Medical Group Oncology / Hematology-San Martin
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: research@sncrf.org

HealthCare Partners Medical Group Oncology / Hematology-Tenaya
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: research@sncrf.org

Hope Cancer Care of Nevada
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: research@sncrf.org

Las Vegas Cancer Center-Medical Center
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: research@sncrf.org

Las Vegas Prostate Cancer Center
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: research@sncrf.org

Las Vegas Urology - Cathedral Rock
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: research@sncrf.org

Las Vegas Urology - Pecos
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: research@sncrf.org

Las Vegas Urology - Smoke Ranch
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: research@smcrf.org

Las Vegas Urology - Sunset
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: research@sncrf.org

OptumCare Cancer Care at Charleston
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: research@sncrf.org

OptumCare Cancer Care at Fort Apache
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: research@sncrf.org

OptumCare Cancer Care at MountainView
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: research@sncrf.org

Radiation Oncology Centers of Nevada Central
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: research@sncrf.org

Radiation Oncology Centers of Nevada Southeast
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: research@sncrf.org

Summerlin Hospital Medical Center
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: research@sncrf.org

Sunrise Hospital and Medical Center
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: research@sncrf.org

University Cancer Center
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: research@sncrf.org

University Medical Center of Southern Nevada
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: research@sncrf.org

Urology Specialists of Nevada - Central
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: research@sncrf.org

Urology Specialists of Nevada - Northwest
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: research@sncrf.org

Urology Specialists of Nevada - Southwest
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: research@sncrf.org

Pahrump
Hope Cancer Care of Nevada-Pahrump
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: research@sncrf.org

Reno
Radiation Oncology Associates
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: research@sncrf.org

Renown Regional Medical Center
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: research@sncrf.org

Saint Mary's Regional Medical Center
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: research@sncrf.org

NY
Bronx
Montefiore Medical Center - Moses Campus
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: eskwak@montefiore.org

Montefiore Medical Center-Einstein Campus
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: eskwak@montefiore.org

Montefiore Medical Center-Weiler Hospital
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: eskwak@montefiore.org

Middletown
Garnet Health Medical Center
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: jgerlach@garnethealth.org

OH
Akron
Cleveland Clinic Akron General
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: CancerAnswer@ccf.org

Beachwood
UHHS-Chagrin Highlands Medical Center
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: CTUReferral@UHhospitals.org

Beavercreek
Indu and Raj Soin Medical Center
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: clinical.trials@daytonncorp.org

Boardman
Saint Elizabeth Boardman Hospital
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: clinical.trials@daytonncorp.org

Centerville
Dayton Physicians LLC-Miami Valley South
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: clinical.trials@daytonncorp.org

Miami Valley Hospital South
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: clinical.trials@daytonncorp.org

Chardon
Geauga Hospital
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: CTUReferral@UHhospitals.org

Cincinnati
Bethesda North Hospital
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: clinicaltrials@sfmc-gi.org

Good Samaritan Hospital - Cincinnati
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: clinicaltrials@sfmc-gi.org

Oncology Hematology Care Inc-Kenwood
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: clinical.trials@daytonncorp.org

TriHealth Cancer Institute-Anderson
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: clinicaltrials@sfmc-gi.org

TriHealth Cancer Institute-Westside
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: clinicaltrials@sfmc-gi.org

Cleveland
Case Western Reserve University
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: CTUReferral@UHhospitals.org

Columbus
Ohio State University Comprehensive Cancer Center
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: Jamesline@osumc.edu

Dayton
Dayton Physician LLC-Miami Valley Hospital North
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: clinical.trials@daytonncorp.org

Good Samaritan Hospital - Dayton
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: clinical.trials@daytonncorp.org

Miami Valley Hospital
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: clinical.trials@daytonncorp.org

Miami Valley Hospital North
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: clinical.trials@daytonncorp.org

Elyria
Mercy Cancer Center-Elyria
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: CTUReferral@UHhospitals.org

Findlay
Armes Family Cancer Center
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: clinical.trials@daytonncorp.org

Blanchard Valley Hospital
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: clinical.trials@daytonncorp.org

Orion Cancer Care
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: clinical.trials@daytonncorp.org

Franklin
Atrium Medical Center-Middletown Regional Hospital
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: clinical.trials@daytonncorp.org

Dayton Physicians LLC-Atrium
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: clinical.trials@daytonncorp.org

Greenville
Dayton Physicians LLC-Wayne
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: clinical.trials@daytonncorp.org

Wayne Hospital
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: clinical.trials@daytonncorp.org

Kettering
First Dayton Cancer Care
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: clinical.trials@daytonncorp.org

Greater Dayton Cancer Center
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: clinical.trials@daytonncorp.org

Kettering Medical Center
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: clinical.trials@daytonncorp.org

Maumee
Toledo Clinic Cancer Centers-Maumee
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact

Toledo Radiation Oncology at Northwest Ohio Onocolgy Center
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact

Mentor
UH Seidman Cancer Center at Lake Health Mentor Campus
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: CTUReferral@UHhospitals.org

Parma
University Hospitals Parma Medical Center
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: CTUReferral@UHhospitals.org

Perrysburg
Mercy Health Perrysburg Cancer Center
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: sheree@columbusccop.org

Sandusky
UH Seidman Cancer Center at Firelands Regional Medical Center
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: CTUReferral@UHhospitals.org

Springfield
Springfield Regional Cancer Center
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: clinical.trials@daytonncorp.org

Springfield Regional Medical Center
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: clinical.trials@daytonncorp.org

Sylvania
ProMedica Flower Hospital
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact

Toledo
Mercy Health - Saint Anne Hospital
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: sheree@columbusccop.org

ProMedica Toledo Hospital / Russell J Ebeid Children's Hospital
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact

Toledo Clinic Cancer Centers-Toledo
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact

Troy
Dayton Physicians LLC-Upper Valley
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: clinical.trials@daytonncorp.org

Upper Valley Medical Center
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: clinical.trials@daytonncorp.org

Warren
Saint Joseph Warren Hospital
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: clinical.trials@daytonncorp.org

Westlake
UHHS-Westlake Medical Center
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: CTUReferral@UHhospitals.org

Youngstown
Saint Elizabeth Youngstown Hospital
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: clinical.trials@daytonncorp.org

OK
Lawton
Cancer Centers of Southwest Oklahoma Research
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact

Oklahoma City
Mercy Hospital Oklahoma City
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact

University of Oklahoma Health Sciences Center
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: ou-clinical-trials@ouhsc.edu

Tulsa
Cancer Treatment Centers of America
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: ctsucontact@westat.com

Oklahoma Cancer Specialists and Research Institute-Tulsa
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact

OR
Baker City
Saint Alphonsus Medical Center-Baker City
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: stephanie.couch@stjoeshealth.org

Ontario
Saint Alphonsus Medical Center-Ontario
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: stephanie.couch@stjoeshealth.org

PA
Abington
Jefferson Abington Hospital
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact

Beaver
UPMC-Heritage Valley Health System Beaver
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact

Chadds Ford
Christiana Care Health System-Concord Health Center
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: mhayden@christianacare.org

Danville
Geisinger Medical Center
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: HemonCCTrials@geisinger.edu

Greensburg
UPMC Cancer Centers - Arnold Palmer Pavilion
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact

Harrisburg
UPMC Pinnacle Cancer Center / Community Osteopathic Campus
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: klitchfield@PINNACLEHEALTH.org

Hazleton
Geisinger Medical Center-Cancer Center Hazleton
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: HemonCCTrials@geisinger.edu

Hershey
Penn State Milton S Hershey Medical Center
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: CTO@hmc.psu.edu

Johnstown
UPMC-Johnstown / John P. Murtha Regional Cancer Center
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact

Lewisburg
Geisinger Medical Oncology-Lewisburg
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: HemonCCTrials@geisinger.edu

Lewistown
Lewistown Hospital
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: HemonCCTrials@geisinger.edu

McKeesport
UPMC Cancer Center at UPMC McKeesport
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact

Moon Township
UPMC-Coraopolis / Heritage Valley Radiation Oncology
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact

Philadelphia
Temple University Hospital
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact

University of Pennsylvania / Abramson Cancer Center
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact

Pittsburgh
UPMC-Magee Womens Hospital
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact

UPMC-Mercy Hospital
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact

UPMC-Passavant Hospital
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact

UPMC-Presbyterian Hospital
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact

UPMC-Saint Clair Hospital Cancer Center
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact

UPMC-Saint Margaret
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact

UPMC-Shadyside Hospital
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact

University of Pittsburgh Cancer Institute (UPCI)
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact

Pottsville
Geisinger Cancer Services-Pottsville
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: HemonCCTrials@geisinger.edu

Sayre
Guthrie Medical Group PC-Robert Packer Hospital
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact

Scranton
Community Medical Center
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: HemonCCTrials@geisinger.edu

Selinsgrove
Geisinger Medical Oncology-Selinsgrove
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: HemonCCTrials@geisinger.edu

Seneca
UPMC Cancer Center at UPMC Northwest
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact

State College
Geisinger Medical Group
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: HemonCCTrials@geisinger.edu

Uniontown
UPMC Uniontown Hospital Radiation Oncology
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact

Washington
UPMC Washington Hospital Radiation Oncology
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: cancer@washingtonhospital.org

West Reading
Reading Hospital
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact

Wilkes-Barre
Geisinger Wyoming Valley / Henry Cancer Center
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: HemonCCTrials@geisinger.edu

Williamsport
UPMC Susquehanna
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact

Willow Grove
Asplundh Cancer Pavilion
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact

PR
Bayamon
Cancer Center-Metro Medical Center Bayamon
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact

Caguas
HIMA San Pablo Oncologic Hospital
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact

Manati
Doctors Cancer Center
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact

Ponce
Instituto Oncologia Moderna Ponce
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact

San Juan
Centro Comprensivo de Cancer de UPR
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: ecog.rss@jimmy.harvard.edu

San Juan City Hospital
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact

San Juan Community Oncology Group
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact

RI
Westerly
Smilow Cancer Hospital Care Center - Westerly
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: canceranswers@yale.edu

SD
Sioux Falls
Sanford Cancer Center Oncology Clinic
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: OncologyClinicTrialsSF@sanfordhealth.org

Sanford USD Medical Center - Sioux Falls
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: OncologyClinicalTrialsSF@SanfordHealth.org

TN
Bristol
Bristol Regional Medical Center
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: justin.reynolds@wellmont.org

Chattanooga
Memorial Hospital
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: clinicaltrials@sfmc-gi.org

Collierville
Baptist Memorial Hospital and Cancer Center-Collierville
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: BCCclintrials@bmhcc.org

Franklin
Vanderbilt-Ingram Cancer Center Cool Springs
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact

Hixson
Pulmonary Medicine Center of Chattanooga-Hixson
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: clinicaltrials@sfmc-gi.org

Johnson City
Wellmont Medical Associates Oncology and Hematology-Johnson City
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: justin.reynolds@wellmont.org

Kingsport
Ballad Health Cancer Care โ€“ Kingsport
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: Justin.reynolds@balladhealth.org

Wellmont Holston Valley Hospital and Medical Center
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: justin.reynolds@wellmont.org

Memphis
Baptist Memorial Hospital and Cancer Center-Memphis
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: BCCclintrials@bmhcc.org

Nashville
Vanderbilt Breast Center at One Hundred Oaks
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact

Vanderbilt University / Ingram Cancer Center
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact

Ooltewah
Memorial GYN Plus
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: clinicaltrials@sfmc-gi.org

TX
Bryan
Saint Joseph Regional Cancer Center
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: clinicaltrials@sfmc-gi.org

Conroe
MD Anderson in The Woodlands
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: askmdanderson@mdanderson.org

Dallas
UT Southwestern / Simmons Cancer Center-Dallas
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: canceranswerline@UTSouthwestern.edu

Fort Worth
UT Southwestern / Simmons Cancer Center-Fort Worth
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: canceranswerline@UTSouthwestern.edu

Houston
Lyndon Baines Johnson General Hospital
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact

M D Anderson Cancer Center
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: askmdanderson@mdanderson.org

MD Anderson West Houston
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: askmdanderson@mdanderson.org

League City
MD Anderson League City
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: askmdanderson@mdanderson.org

Richardson
UT Southwestern Clinical Center at Richardson / Plano
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: Suzanne.cole@utsouthwestern.edu

San Antonio
University of Texas Health Science Center at San Antonio
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: phoresearchoffice@uthscsa.edu

Sugar Land
MD Anderson in Sugar Land
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: askmdanderson@mdanderson.org

UT
American Fork
American Fork Hospital / Huntsman Intermountain Cancer Center
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: officeofresearch@imail.org

Cedar City
Sandra L Maxwell Cancer Center
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: officeofresearch@imail.org

Farmington
Farmington Health Center
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: cancerinfo@hci.utah.edu

Logan
Logan Regional Hospital
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: officeofresearch@imail.org

Murray
Intermountain Medical Center
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: officeofresearch@imail.org

Ogden
McKay-Dee Hospital Center
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: officeofresearch@imail.org

Provo
Utah Valley Regional Medical Center
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: officeofresearch@imail.org

Riverton
Riverton Hospital
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: officeofresearch@imail.org

Saint George
Saint George Regional Medical Center
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: officeofresearch@imail.org

Salt Lake City
Huntsman Cancer Institute / University of Utah
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: cancerinfo@hci.utah.edu

LDS Hospital
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: officeofresearch@imail.org

Utah Cancer Specialists-Salt Lake City
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: officeofresearch@imail.org

South Jordan
South Jordan Health Center
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: cancerinfo@hci.utah.edu

VA
Bristol
Wellmont Medical Associates-Bristol
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: justin.reynolds@wellmont.org

Charlottesville
University of Virginia Cancer Center
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: PAS9E@virginia.edu

Martinsville
Sovah Health Martinsville
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: sharon.hubbard@lpnt.net

Mechanicsville
Bon Secours Memorial Regional Medical Center
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: Jaime_scott@bshsi.org

Midlothian
Bon Secours Saint Francis Medical Center
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: Jaime_scott@bshsi.org

Norfolk
Bon Secours DePaul Medical Center
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: Jaime_scott@bshsi.org

Norton
Southwest VA Regional Cancer Center
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: justin.reynolds@wellmont.org

Portsmouth
Bon Secours Maryview Medical Center
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: Jaime_scott@bshsi.org

Richmond
Bon Secours Cancer Institute at Reynolds Crossing
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: Jaime_scott@bshsi.org

Bon Secours Saint Mary's Hospital
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: Jaime_scott@bshsi.org

Suffolk
Bon Secours Health Center at Harbour View
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: Jaime_scott@bshsi.org

WI
Appleton
ThedaCare Regional Cancer Center
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: ResearchDept@thedacare.org

Ashland
Duluth Clinic Ashland
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: CancerTrials@EssentiaHealth.org

Northwest Wisconsin Cancer Center
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: CancerTrials@EssentiaHealth.org

Chippewa Falls
Marshfield Clinic-Chippewa Center
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: oncology.clinical.trials@marshfieldresearch.org

Eau Claire
Marshfield Medical Center-EC Cancer Center
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: oncology.clinical.trials@marshfieldresearch.org

Green Bay
Saint Vincent Hospital Cancer Center Green Bay
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: ewd_research_admin@hshs.org

Saint Vincent Hospital Cancer Center at Saint Mary's
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: ewd_research_admin@hshs.org

Johnson Creek
UW Cancer Center Johnson Creek
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: lynda.persico@uwmf.wisc.edu

Ladysmith
Marshfield Clinic - Ladysmith Center
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: oncology.clinical.trials@marshfieldresearch.org

Madison
University of Wisconsin Carbone Cancer Center
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact

Manitowoc
Holy Family Memorial Hospital
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact

Marshfield
Marshfield Medical Center-Marshfield
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: oncology.clinical.trials@marshfieldresearch.org

Menomonee Falls
Froedtert Menomonee Falls Hospital
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact

Milwaukee
Medical College of Wisconsin
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact

Minocqua
Marshfield Clinic-Minocqua Center
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: oncology.clinical.trials@marshfieldresearch.org

New Richmond
Cancer Center of Western Wisconsin
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: mmcorc@healthpartners.com

Oconto Falls
Saint Vincent Hospital Cancer Center at Oconto Falls
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: ewd_research_admin@hshs.org

Rice Lake
Marshfield Medical Center-Rice Lake
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: oncology.clinical.trials@marshfieldresearch.org

Stevens Point
Marshfield Medical Center-River Region at Stevens Point
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: oncology.clinical.trials@marshfieldresearch.org

Sturgeon Bay
Saint Vincent Hospital Cancer Center at Sturgeon Bay
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: ewd_research_admin@hshs.org

Wausau
Marshfield Clinic-Wausau Center
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: oncology.clinical.trials@marshfieldresearch.org

West Bend
Froedtert West Bend Hospital / Kraemer Cancer Center
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact

Weston
Marshfield Medical Center - Weston
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: oncology.clinical.trials@marshfieldresearch.org

Wisconsin Rapids
Marshfield Clinic - Wisconsin Rapids Center
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: oncology.clinical.trials@marshfieldresearch.org

WV
Charleston
West Virginia University Charleston Division
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact

WY
Cheyenne
Cheyenne Regional Medical Center-West
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: ccrp@co-cancerresearch.org

Cody
Billings Clinic-Cody
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: research@billingsclinic.org

Sheridan
Welch Cancer Center
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: mccinfo@mtcancer.org

PRIMARY OBJECTIVES:
I. To assess whether the addition of 6 cycles of cabazitaxel to abiraterone acetate in patients with castration-resistant prostate cancer (CRPC) that have previously received docetaxel and androgen deprivation therapy (ADT) for hormone-sensitive prostate cancer (HSPC) can improve progression-free survival (PFS) compared to abiraterone acetate alone.

SECONDARY OBJECTIVES:
I. To assess whether the addition of 6 cycles of cabazitaxel to abiraterone acetate in patients with CRPC that have previously received docetaxel and ADT for HSPC can increase the percentage of change in prostate-specific antigen (PSA) from baseline to week 12 of treatment as well as the maximum decline in PSA that occurs at any point after treatment compared to abiraterone acetate alone.
II. To assess whether the addition of 6 cycles of cabazitaxel to abiraterone acetate in patients with CRPC that have previously received docetaxel for HSPC can prolong time to PSA progression compared to abiraterone acetate alone.
III. To assess whether the addition of 6 cycles of cabazitaxel to abiraterone acetate in patients with CRPC that have previously received docetaxel for HSPC can improve radiographic response (per Response Evaluation Criteria in Solid Tumors [RECIST] 1.1) compared to abiraterone acetate alone.
IV. To assess whether the addition of 6 cycles of cabazitaxel to abiraterone acetate in patients with CRPC that have previously received docetaxel and ADT for HSPC can prolong the overall survival (OS) compared to abiraterone acetate alone.
V. To assess safety and tolerability of the combination of 6 cycles of cabazitaxel and abiraterone acetate.

EXPLORATORY OBJECTIVES:
I. To examine whether patients with circulating tumor cells (CTCs) positive for AR-V7 at baseline have a longer radiographic or clinical PFS to the combination of cabazitaxel and abiraterone acetate vs. abiraterone acetate alone.
II. To examine whether the addition of cabazitaxel to abiraterone acetate can change the AR-V7 status of patients who are positive at study entry.
III. To examine whether the addition of cabazitaxel to abiraterone acetate has any impact on future development of AR-V7 positivity at the time of disease progression.

IMAGING OBJECTIVES:
I. To assess if the changes in total tumor burden from baseline to week 12 as assessed with sodium fluoride (NaF) positron emission tomography (PET)/computed tomography (CT) will differ between two arms.
II. To correlate total tumor burden at the baseline as assessed with NaF PET/CT with the PFS.
III. To correlate heterogeneity of response from baseline to week 12 as assessed with NaF PET/CT with the PFS.

TOBACCO USE OBJECTIVES:
I. To determine the effects of tobacco, operationalized as combustible tobacco (1a), other forms of tobacco (1b), and environmental tobacco exposure (ETS) (1c) on provider-reported cancer-treatment toxicity (adverse events (both clinical and hematologic) and dose modifications).
II. To determine the effects of tobacco on patient-reported physical symptoms and psychological symptoms.
III. To examine quitting behaviors and behavioral counseling/support and cessation medication utilization.
IV. To explore the effect of tobacco use and exposure on treatment duration, relative dose intensity, and therapeutic benefit

OUTLINE: Patients are randomized to 1 of 2 arms.

ARM A: Patients receive abiraterone acetate orally (PO) once daily (QD) on days 1-21, prednisone PO twice daily (BID) on days 1-21. Courses of abiraterone acetate and prednisone repeat every 21 days in the absence of disease progression or unacceptable toxicity. Patients receive cabazitaxel intravenously (IV) over 1 hour on day 1, and treatment with cabazitaxel repeats every 21 days for up to 6 courses in the absence of disease progression or unacceptable toxicity. Patients also receive standard of care antiandrogen therapy with either luteinizing hormone-releasing hormone (LHRH) agonist or antagonist, or surgical castration with bilateral orchiectomy.

ARM B: Patients receive abiraterone acetate and prednisone as in Arm A. Patients also receive standard of care antiandrogen therapy with either LHRH agonist or antagonist, or surgical castration with bilateral orchiectomy.

After completion of study treatment, patients are followed up every 3 or 6 months and then annually for up to 5 years.

Interactive content above is from the official study record on the National Cancer Institute website, cancer.gov.


The ECOG-ACRIN Cancer Research Group designed and conducted this trial with funding from the National Cancer Institute through its National Clinical Trials Network.


EA8153 / CHAARTED2 (Closed)
ECOG-ACRIN Cancer Research Group