Lung Cancer

EA5181



Testing the Addition of an Antibody to Standard Chemoradiation followed by the Antibody for One Year to Standard Chemoradiation followed by One Year of the Antibody in Patients with Unresectable Stage III Non-Small Cell Lung Cancer

STATUS: Active


This phase III trial studies how well an antibody (durvalumab) with chemotherapy and radiation therapy (chemoradiation) works in treating patients with stage III non-small cell lung cancer that cannot be removed by surgery (unresectable). Immunotherapy with monoclonal antibodies, such as durvalumab, may help the bodyโ€™s immune system attack the cancer, and may interfere with the ability of tumor cells to grow and spread. This study is being done to see if adding durvalumab to standard chemoradiation followed by additional durvalumab can extend patients life and / or prevent the tumor from coming back compared to the usual approach of chemoradiation alone followed by durvalumab.
  • STEP 1 INCLUSION ELIGIBILITY CRITERIA - CONCURRENT THERAPY

  • Patient must be >= 18 years old

  • Patient must have one of the following: * Newly diagnosed stage IIIA/B/C non-small cell lung cancer (NSCLC) (per the American Joint Committee on Cancer [AJCC] 8th edition) that is unresectable and is histologically and/or cytologically confirmed * Nodal recurrence after surgery for early stage NSCLC

  • Patient must have an Eastern Cooperative Oncology Group (ECOG) performance status of 0 or 1

  • Patient must have a body weight > 30 kg

  • Patient must not have unintentional weight loss > 10% within 30 days prior to registration

  • Patient must have a baseline electrocardiography (ECG) obtained within 6 weeks prior to registration

  • Patient must have measurable disease per Response Evaluation Criteria in Solid Tumors (RECIST) version (v)1.1. Baseline imaging assessments and measurements used to evaluate all measurable or non-measurable sites of disease must be done within 4 weeks prior to registration

  • Absolute neutrophil count (ANC) >= 1500 cells/uL (obtained =< 7 days prior to registration)

  • White blood cells (WBC) counts >= 2500/uL (obtained =< 7 days prior to registration)

  • Platelet count >= 100,000/uL (obtained =< 7 days prior to registration)

  • Hemoglobin >= 9.0 g/dL (obtained =< 7 days prior to registration)

  • Total bilirubin =< 1.5 x institutional upper limit of normal (ULN) with the following exception: patients with known Gilbert disease who have serum bilirubin level < 3 x ULN may be enrolled (obtained =< 7 days prior to registration)

  • Aspartate aminotransferase (AST) and alanine transaminase (ALT) =< 3.0 x institutional ULN (obtained =< 7 days prior to registration)

  • Serum creatinine =< 1.5 x institutional ULN or creatinine clearance >= 45 mL/min on the basis of the Cockcroft-Gault glomerular filtration rate estimation (obtained =< 7 days prior to registration)

  • Patient must have pulmonary function tests (PFTs) with both forced expiratory volume in 1 second (FEV1) and diffusion capacity of the lung for carbon monoxide (DLCO) >= 40% of predicted, obtained within 5 months prior to registration

  • Patient is expected to have lung volume (V)20 of =< 35%, after radiation oncologist views pre-treatment work up

  • Patients with nodal recurrence after surgery for early-stage NSCLC are eligible if the following criteria are met: * No prior chemotherapy or radiation was ever administered for this lung cancer originally or for recurrence prior to entering this protocol * Prior curative-intent surgery was at least 90 days prior to the nodal recurrence * No prior radiation was administered to the region of study cancer that would cause overlap of treatment fields

  • Patients who are human immunodeficiency virus (HIV) positive may participate in the study IF they meet all of the following eligibility requirements: * They must be stable on their anti-retroviral regimen, and they must be healthy from an HIV perspective * They must have a CD4 count of greater than 250 cells/mcL, obtained within 6 months prior to registration * They must not be receiving prophylactic therapy for an opportunistic infection

  • Patients with a prior or concurrent malignancy whose natural history or treatment does not have the potential to interfere with the safety or efficacy assessment of the investigational regimen are eligible for this trial. Patients must not have had chemotherapy or radiotherapy within 4 weeks (6 weeks for nitrosoureas or mitomycin C) prior to registration

  • Patient must not be pregnant or breast-feeding due to the potential harm to an unborn fetus and possible risk for adverse events in nursing infants with the treatment regimens being used.

  • All patients of childbearing potential must have a negative blood test or urine study, with a minimum sensitivity 50 mlU/L or equivalent units of HCG, within 7 days prior to registration to rule out pregnancy. A patient of childbearing potential is anyone, regardless of sexual orientation or whether they have undergone tubal ligation, who meets the following criteria: 1) has achieved menarche at some point, 2) has not undergone a hysterectomy or bilateral oophorectomy; or 3) has not been naturally postmenopausal (amenorrhea following cancer therapy does not rule out childbearing potential) for at least 24 consecutive months (i.e., has had menses at any time in the preceding 24 consecutive months).

  • Patients must not expected to conceive or father children by using accepted and highly effective method(s) of contraception during sexual intercourse for at least one week prior to the start of treatment, during protocol treatment, and continue for 90 days after the last dose of protocol treatment. * Highly effective methods of contraception include Etonogestrel-releasing implants (Implanon or Norplant), Intravaginal: Ethinylestradiol/etonogestrel-releasing intravaginal devices: e.g., NuvaRing, injection: Medroxyprogesterone injection: e.g., Depo-Provera, combined pill: Normal and low dose combined oral contraceptive pill, patch: Norelgestromin/ethinylestradiol-releasing transdermal system: e.g., Ortho Evra, Minipillc: Progesterone based oral contraceptive pill using desogestrel: Cerazette is currently the only highly effective progesterone based pill * Methods that are considered inadequate include male or female condom with or without spermicide; female cap, diaphragm, or sponge with or without spermicide; non-copper containing intrauterine device; progestogen-only oral hormonal contraceptive pills where inhibition of ovulation is not the primary mode of action [excluding Cerazette/desogestrel which is considered highly effective]; and triphasic combined oral contraceptive pills)

  • STEP 1 EXCLUSION ELIGIBILITY CRITERIA - CONCURRENT THERAPY

  • Patient must not have any active, known or suspected autoimmune disease and neuromuscular paraneoplastic syndromes including, but not limited to myasthenia gravis, Lambert-Eaton myasthenic syndrome, limbic encephalitis, myositis, Guillain-Barrรฉ, systemic lupus erythematosus, and systemic sclerosis. Patients with type I diabetes mellitus requiring insulin, hypothyroidism only requiring hormone replacement, skin disorders (such as vitiligo, psoriasis, or alopecia) not requiring systemic treatment, or conditions not expected to recur in the absence of an external trigger are eligible

  • Patient must not have a history of active hepatitis B (chronic or acute) or hepatitis C infection. Patients with past or resolved hepatitis B infection (defined as having a negative hepatitis B surface antigen [HBsAg] test and a positive anti-HBc [antibody to hepatitis B core antigen] antibody test) are eligible. Patients positive for hepatitis C virus (HCV) antibody are eligible only if polymerase chain reaction (PCR) is negative for hepatitis C virus ribonucleic acid (HCV RNA)

  • Patient must not have a known active tuberculosis infection

  • Patient must not have any severe infections within 4 weeks prior to registration including, but not limited to, hospitalization for complications of infection, bacteremia, or severe pneumonia

  • Patient must not have signs or symptoms of severe infection (sepsis) within 2 weeks prior registration

  • Patient must not have been treated with systemic immunostimulatory agents (including but not limited to interferon-a [IFN-a], interleukin [IL]-2) within 6 weeks or five half-lives of the drug (whichever is shorter) prior to registration; or treated with an investigational agent within 4 weeks prior to registration (or within five half-lives of the investigational agent, whichever is longer)

  • Patient must not have a history of severe allergic, anaphylactic, or other hypersensitivity reactions to chimeric or humanized antibodies or fusion proteins

  • Patient must not have been treated with systemic immunosuppressive medications (equivalent to > 10 mg prednisone per day) or other immunosuppressive medications within 7 days prior to registration. Inhaled or topical steroids and adrenal replacement steroid doses equivalent to > 10 mg prednisone per day are permitted in the absence of active autoimmune disease

  • Patient must not have had a prior allogeneic bone marrow transplantation or prior solid organ transplantation

  • Patient must not have a history of idiopathic pulmonary fibrosis, pneumonitis (including drug induced), organizing pneumonia (i.e., bronchiolitis obliterans, cryptogenic organizing pneumonia, etc.), or evidence of active pneumonitis on screening chest computed tomography (CT) scan within 4 weeks prior to registration

  • Patient must not have had any prior systemic treatment with an anti-PD-1, anti-PD-L1, anti-PD-L2, anti-CTLA-4 antibody, or any other antibody or drug specifically targeting T-cell costimulation or immune checkpoint pathways

  • Patient with known history or current symptoms of cardiac disease, or history of treatment with cardiotoxic agents, should have a clinical risk assessment and severity of cardiac symptoms. Symptoms should be stable over the past 3 months. Specifically, patient must not have coronary artery bypass grafting, myocardial infarction, acute coronary syndrome severe/unstable angina, stroke, transient ischemic attack, or heart failure hospitalization within 3 months prior to registration

  • Patient must not have an uncontrolled intercurrent illness, including but not limited to, ongoing or active infection, symptomatic congestive heart failure, uncontrolled hypertension, unstable angina pectoris, cardiac arrhythmia, interstitial lung disease, serious chronic gastrointestinal conditions associated with diarrhea, or psychiatric illness/social situations that would limit compliance with study requirement, substantially increase risk of incurring adverse events (AEs) or compromise the ability of the patient to give written informed consent

  • Patient must not have received a live, attenuated vaccine within 4 weeks prior to registration

  • Patient must not have had past radiation to the current intended treatment site

  • Patient must not donate blood or sperm while on study treatment

  • STEP 2 INCLUSION ELIGIBILITY CRITERIA - CONSOLIDATION

  • Patients with any > grade 2 non-hematologic or > grade 3 hematologic toxicities must recover to grade 2 (or less) within 45 days after the end of Step 1 concurrent chemo/radiation, with the exception of alopecia and vitiligo

  • STEP 2 EXCLUSION ELIGIBILITY CRITERIA - CONSOLIDATION

  • Patient must not receive any non-protocol anti-cancer therapy after the end of Step 1 chemo/radiation or during Step 2 consolidation

  • Patients with suspected cases of >= grade 2 pneumonitis (non-infectious) are not eligible for Step 2 consolidative MEDI4736 (durvalumab) and will proceed onto follow-up instead

  • Patient must not have disease progression on the first post-treatment (Step 1 for concurrent chemo/radiation) chest CT scan, which must be obtained within 14 days after the last dose of radiation therapy. If so, the patient is not eligible for Step 2 consolidative MEDI4736 (durvalumab) and will proceed onto follow-up instead

United States
AK
Anchorage
Alaska Breast Care and Surgery LLC
Status: ACTIVE
Contact: Site Public Contact
Email: AKPAMC.OncologyResearchSupport@providence.org

Alaska Oncology and Hematology LLC
Status: ACTIVE
Contact: Site Public Contact
Email: AKPAMC.OncologyResearchSupport@providence.org

Alaska Women's Cancer Care
Status: ACTIVE
Contact: Site Public Contact
Email: AKPAMC.OncologyResearchSupport@providence.org

Anchorage Associates in Radiation Medicine
Status: ACTIVE
Contact: Site Public Contact
Email: AKPAMC.OncologyResearchSupport@providence.org

Anchorage Oncology Centre
Status: ACTIVE
Contact: Site Public Contact
Email: AKPAMC.OncologyResearchSupport@providence.org

Anchorage Radiation Therapy Center
Status: ACTIVE
Contact: Site Public Contact
Email: AKPAMC.OncologyResearchSupport@providence.org

Katmai Oncology Group
Status: ACTIVE
Contact: Site Public Contact
Email: AKPAMC.OncologyResearchSupport@providence.org

Providence Alaska Medical Center
Status: ACTIVE
Contact: Site Public Contact
Email: AKPAMC.OncologyResearchSupport@providence.org

Fairbanks
Fairbanks Memorial Hospital
Status: ACTIVE
Contact: Site Public Contact
Email: Veronica.Stevenson@foundationhealth.org

AR
Ft. Smith
Mercy Hospital Fort Smith
Status: ACTIVE
Contact: Site Public Contact

Hot Springs
CHI Saint Vincent Cancer Center Hot Springs
Status: TEMPORARILY_CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: ResearchInstituteInquiries@CommonSpirit.org

Jonesboro
NEA Baptist Memorial Hospital and Fowler Family Cancer Center - Jonesboro
Status: ACTIVE
Contact: Site Public Contact
Email: Emily.Carvell@bmhcc.org

Little Rock
University of Arkansas for Medical Sciences
Status: ACTIVE
Contact: Site Public Contact

AZ
Gilbert
Banner MD Anderson Cancer Center
Status: ACTIVE
Contact: Site Public Contact

Kingman
Kingman Regional Medical Center
Status: ACTIVE
Contact: Site Public Contact
Email: research@sncrf.org

Phoenix
Cancer Center at Saint Joseph's
Status: ACTIVE
Contact: Site Public Contact
Email: CancerInstitute@DignityHealth.org

Sun City
Banner Boswell Medical Center
Status: ACTIVE
Contact: Site Public Contact
Email: BMDACCResearch@bannerhealth.com

Tucson
Banner University Medical Center - Tucson
Status: ACTIVE
Contact: Site Public Contact
Email: UACC-NCTN@uacc.arizona.edu

University of Arizona Cancer Center-North Campus
Status: ACTIVE
Contact: Site Public Contact

University of Arizona Cancer Center-Orange Grove Campus
Status: ACTIVE
Contact: Site Public Contact

CA
Arroyo Grande
Mission Hope Medical Oncology - Arroyo Grande
Status: ACTIVE
Contact: Site Public Contact
Email: ResearchInstituteInquiries@CommonSpirit.org

PCR Oncology
Status: ACTIVE
Contact: Site Public Contact
Email: research@sncrf.org

Auburn
Sutter Auburn Faith Hospital
Status: ACTIVE
Contact: Site Public Contact
Email: hempell@sutterhealth.org

Sutter Cancer Centers Radiation Oncology Services-Auburn
Status: ACTIVE
Contact: Site Public Contact
Email: hempell@sutterhealth.org

Berkeley
Alta Bates Summit Medical Center-Herrick Campus
Status: ACTIVE
Contact: Site Public Contact
Email: hempell@sutterhealth.org

Burbank
Providence Saint Joseph Medical Center / Disney Family Cancer Center
Status: ACTIVE
Contact: Site Public Contact
Email: Najee.Boucher@providence.org

Burlingame
Mills-Peninsula Medical Center
Status: TEMPORARILY_CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: hempell@sutterhealth.org

Cameron Park
Sutter Cancer Centers Radiation Oncology Services-Cameron Park
Status: ACTIVE
Contact: Site Public Contact
Email: hempell@sutterhealth.org

Castro Valley
Eden Hospital Medical Center
Status: ACTIVE
Contact: Site Public Contact
Email: hempell@sutterhealth.org

Davis
Sutter Davis Hospital
Status: ACTIVE
Contact: Site Public Contact
Email: hempell@sutterhealth.org

El Segundo
21st Century Oncology - El Segundo
Status: TEMPORARILY_CLOSED_TO_ACCRUAL
Contact: Site Public Contact

Fremont
Palo Alto Medical Foundation-Fremont
Status: ACTIVE
Contact: Site Public Contact
Email: hempell@sutterhealth.org

Modesto
Memorial Medical Center
Status: ACTIVE
Contact: Site Public Contact
Email: hempell@sutterhealth.org

Mountain View
Palo Alto Medical Foundation-Camino Division
Status: ACTIVE
Contact: Site Public Contact
Email: hempell@sutterhealth.org

Palo Alto Medical Foundation-Gynecologic Oncology
Status: ACTIVE
Contact: Site Public Contact
Email: hempell@sutterhealth.org

Palo Alto
Palo Alto Medical Foundation Health Care
Status: ACTIVE
Contact: Site Public Contact
Email: hempell@sutterhealth.org

Roseville
Sutter Cancer Centers Radiation Oncology Services-Roseville
Status: ACTIVE
Contact: Site Public Contact
Email: hempell@sutterhealth.org

Sutter Roseville Medical Center
Status: ACTIVE
Contact: Site Public Contact
Email: hempell@sutterhealth.org

Sacramento
Sutter Medical Center Sacramento
Status: ACTIVE
Contact: Site Public Contact
Email: hempell@sutterhealth.org

University of California Davis Comprehensive Cancer Center
Status: ACTIVE
Contact: Site Public Contact

San Francisco
California Pacific Medical Center-Pacific Campus
Status: ACTIVE
Contact: Site Public Contact
Email: hempell@sutterhealth.org

San Luis Obispo
Pacific Central Coast Health Center-San Luis Obispo
Status: ACTIVE
Contact: Site Public Contact
Email: ResearchInstituteInquiries@CommonSpirit.org

Santa Cruz
Palo Alto Medical Foundation-Santa Cruz
Status: ACTIVE
Contact: Site Public Contact
Email: hempell@sutterhealth.org

Santa Maria
Mission Hope Medical Oncology - Santa Maria
Status: ACTIVE
Contact: Site Public Contact
Email: ResearchInstituteInquiries@CommonSpirit.org

Santa Rosa
Sutter Pacific Medical Foundation
Status: ACTIVE
Contact: Site Public Contact
Email: hempell@sutterhealth.org

Sunnyvale
Palo Alto Medical Foundation-Sunnyvale
Status: ACTIVE
Contact: Site Public Contact
Email: hempell@sutterhealth.org

Vacaville
Sutter Cancer Centers Radiation Oncology Services-Vacaville
Status: ACTIVE
Contact: Site Public Contact
Email: hempell@sutterhealth.org

Vallejo
Sutter Solano Medical Center / Cancer Center
Status: ACTIVE
Contact: Site Public Contact
Email: hempell@sutterhealth.org

CO
Aurora
Rocky Mountain Cancer Centers-Aurora
Status: ACTIVE
Contact: Site Public Contact
Email: info@westernstatesncorp.org

The Medical Center of Aurora
Status: ACTIVE
Contact: Site Public Contact
Email: info@westernstatesncorp.org

Boulder
Boulder Community Foothills Hospital
Status: ACTIVE
Contact: Site Public Contact
Email: info@westernstatesncorp.org

Boulder Community Hospital
Status: ACTIVE
Contact: Site Public Contact
Email: jbloomfield@co-cancerresearch.org

Rocky Mountain Cancer Centers-Boulder
Status: ACTIVE
Contact: Site Public Contact
Email: info@westernstatesncorp.org

Centennial
Rocky Mountain Cancer Centers - Centennial
Status: ACTIVE
Contact: Site Public Contact
Email: info@westernstatesncorp.org

Colorado Springs
Penrose-Saint Francis Healthcare
Status: ACTIVE
Contact: Site Public Contact
Email: ResearchTracking@Centura.Org

Rocky Mountain Cancer Centers-Penrose
Status: ACTIVE
Contact: Site Public Contact
Email: ResearchTracking@Centura.Org

Saint Francis Cancer Center
Status: ACTIVE
Contact: Site Public Contact
Email: ResearchTracking@Centura.Org

Denver
Cancer Center of Colorado at Sloan's Lake
Status: TEMPORARILY_CLOSED_TO_ACCRUAL
Contact: Site Public Contact

Colorado Blood Cancer Institute
Status: ACTIVE
Contact: Site Public Contact
Email: info@westernstatesncorp.org

National Jewish Health-Main Campus
Status: TEMPORARILY_CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: glicht@co-cancerresearch.org

Porter Adventist Hospital
Status: ACTIVE
Contact: Site Public Contact
Email: ResearchTracking@Centura.Org

Presbyterian - Saint Lukes Medical Center - Health One
Status: ACTIVE
Contact: Site Public Contact
Email: info@westernstatesncorp.org

Rocky Mountain Cancer Centers-Midtown
Status: ACTIVE
Contact: Site Public Contact
Email: info@westernstatesncorp.org

Rocky Mountain Cancer Centers-Rose
Status: ACTIVE
Contact: Site Public Contact
Email: info@westernstatesncorp.org

Rose Medical Center
Status: ACTIVE
Contact: Site Public Contact
Email: ccrp@co-cancerresearch.org

SCL Health Saint Joseph Hospital
Status: TEMPORARILY_CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: alan.franklin@sclhealth.org

The Women's Imaging Center
Status: ACTIVE
Contact: Site Public Contact
Email: info@westernstatesncorp.org

Western Surgical Care
Status: ACTIVE
Contact: Site Public Contact

Durango
Mercy Medical Center
Status: ACTIVE
Contact: Site Public Contact
Email: ResearchTracking@Centura.Org

Southwest Oncology PC
Status: ACTIVE
Contact: Site Public Contact
Email: ResearchTracking@Centura.Org

Englewood
Mountain Blue Cancer Care Center - Swedish
Status: ACTIVE
Contact: Site Public Contact
Email: info@westernstatesncorp.org

Rocky Mountain Cancer Centers - Swedish
Status: ACTIVE
Contact: Site Public Contact
Email: info@westernstatesncorp.org

Swedish Medical Center
Status: ACTIVE
Contact: Site Public Contact
Email: info@westernstatesncorp.org

The Melanoma and Skin Cancer Institute
Status: ACTIVE
Contact: Site Public Contact
Email: ryan.weight@theskincancerinstitute.com

Golden
National Jewish Health-Western Hematology Oncology
Status: TEMPORARILY_CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: glicht@co-cancerresearch.org

Grand Junction
Saint Mary's Hospital and Regional Medical Center
Status: TEMPORARILY_CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: ccrp@co-cancerresearch.org

Greeley
North Colorado Medical Center
Status: TEMPORARILY_CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: info@westernstatesncorp.org

Lafayette
Good Samaritan Medical Center
Status: TEMPORARILY_CLOSED_TO_ACCRUAL
Contact: Site Public Contact

Lakewood
Rocky Mountain Cancer Centers-Lakewood
Status: ACTIVE
Contact: Site Public Contact
Email: info@westernstatesncorp.org

Saint Anthony Hospital
Status: ACTIVE
Contact: Site Public Contact
Email: ResearchTracking@Centura.Org

Littleton
Littleton Adventist Hospital
Status: ACTIVE
Contact: Site Public Contact
Email: ResearchTracking@Centura.Org

Rocky Mountain Cancer Centers-Littleton
Status: ACTIVE
Contact: Site Public Contact
Email: info@westernstatesncorp.org

Lone Tree
Rocky Mountain Cancer Centers-Sky Ridge
Status: ACTIVE
Contact: Site Public Contact
Email: info@westernstatesncorp.org

Sky Ridge Medical Center
Status: ACTIVE
Contact: Site Public Contact
Email: info@westernstatesncorp.org

Longmont
Longmont United Hospital
Status: ACTIVE
Contact: Site Public Contact
Email: ResearchTracking@Centura.Org

Rocky Mountain Cancer Centers-Longmont
Status: TEMPORARILY_CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: ResearchTracking@Centura.Org

Loveland
McKee Medical Center
Status: TEMPORARILY_CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: info@westernstatesncorp.org

Parker
Parker Adventist Hospital
Status: ACTIVE
Contact: Site Public Contact
Email: ResearchTracking@Centura.Org

Pueblo
Saint Mary Corwin Medical Center
Status: ACTIVE
Contact: Site Public Contact
Email: ResearchTracking@Centura.Org

Thornton
National Jewish Health-Northern Hematology Oncology
Status: TEMPORARILY_CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: glicht@co-cancerresearch.org

Rocky Mountain Cancer Centers-Thornton
Status: ACTIVE
Contact: Site Public Contact
Email: info@westernstatesncorp.org

Wheat Ridge
SCL Health Lutheran Medical Center
Status: TEMPORARILY_CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: ccrp@co-cancerresearch.org

DE
Dover
Bayhealth Hospital Kent Campus
Status: ACTIVE
Contact: Site Public Contact
Email: mary_ella_quillen@bayhealth.org

Frankford
Beebe South Coastal Health Campus
Status: ACTIVE
Contact: Site Public Contact
Email: Dmiskin@Beebehealthcare.org

Lewes
Beebe Medical Center
Status: ACTIVE
Contact: Site Public Contact
Email: Dmiskin@Beebehealthcare.org

Milford
Bayhealth Hospital Sussex Campus
Status: ACTIVE
Contact: Site Public Contact
Email: jenni_glick@bayhealth.org

Newark
Christiana Care Health System-Christiana Hospital
Status: ACTIVE
Contact: Site Public Contact
Email: mhayden@christianacare.org

Delaware Clinical and Laboratory Physicians PA
Status: ACTIVE
Contact: Site Public Contact
Email: mhayden@christianacare.org

Helen F Graham Cancer Center
Status: ACTIVE
Contact: Site Public Contact
Email: mhayden@christianacare.org

Medical Oncology Hematology Consultants PA
Status: ACTIVE
Contact: Site Public Contact
Email: mhayden@christianacare.org

Rehoboth Beach
Beebe Health Campus
Status: ACTIVE
Contact: Site Public Contact
Email: Dmiskin@Beebehealthcare.org

Seaford
TidalHealth Nanticoke / Allen Cancer Center
Status: TEMPORARILY_CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: anna-maria.howard@peninsula.org

Wilmington
Christiana Care Health System-Wilmington Hospital
Status: ACTIVE
Contact: Site Public Contact
Email: mhayden@christianacare.org

FL
Aventura
GenesisCare USA - Aventura
Status: ACTIVE
Contact: Site Public Contact
Email: Rudi.Ross@usa.genesiscare.com

GenesisCare USA - Aventura FP
Status: ACTIVE
Contact: Site Public Contact
Email: Rudi.Ross@usa.genesiscare.com

Boca Raton
GenesisCare USA - Boca Ration FP06
Status: ACTIVE
Contact: Site Public Contact
Email: Rudi.Ross@usa.genesiscare.com

GenesisCare USA - Boca Raton FP02
Status: ACTIVE
Contact: Site Public Contact
Email: Rudi.Ross@usa.genesiscare.com

Fort Lauderdale
Holy Cross Hospital
Status: ACTIVE
Contact: Site Public Contact

Key West
GenesisCare USA - Key West
Status: ACTIVE
Contact: Site Public Contact
Email: Rudi.Ross@usa.genesiscare.com

Lakeland
The Watson Clinic
Status: ACTIVE
Contact: Site Public Contact

Lakewood Ranch
GenesisCare USA - Lakewood Ranch
Status: ACTIVE
Contact: Site Public Contact
Email: Rudi.Ross@usa.genesiscare.com

Palm Beach Gardens
GenesisCare USA - Palm Beach Gardens
Status: ACTIVE
Contact: Site Public Contact
Email: Rudi.Ross@usa.genesiscare.com

Plantation
GenesisCare USA - Plantation
Status: ACTIVE
Contact: Site Public Contact
Email: Rudi.Ross@usa.genesiscare.com

Tampa
Moffitt Cancer Center
Status: ACTIVE
Contact: Site Public Contact
Email: ClinicalTrials@moffitt.org

Moffitt Cancer Center - McKinley Campus
Status: ACTIVE
Contact: Site Public Contact
Email: ClinicalTrials@moffitt.org

Moffitt Cancer Center-International Plaza
Status: ACTIVE
Contact: Site Public Contact
Email: ClinicalTrials@moffitt.org

West Palm Beach
Good Samaritan Medical Center
Status: ACTIVE
Contact: Site Public Contact

Weston
Cleveland Clinic-Weston
Status: ACTIVE
Contact: Site Public Contact
Email: CancerAnswer@ccf.org

GA
Atlanta
Emory University Hospital / Winship Cancer Institute
Status: ACTIVE
Contact: Site Public Contact

Emory University Hospital Midtown
Status: ACTIVE
Contact: Site Public Contact

Savannah
Lewis Cancer and Research Pavilion at Saint Joseph's / Candler
Status: ACTIVE
Contact: Site Public Contact
Email: underberga@sjchs.org

Thomasville
Lewis Hall Singletary Oncology Center
Status: ACTIVE
Contact: Site Public Contact
Email: ecog.rss@jimmy.harvard.edu

GU
Tamuning
FHP Health Center-Guam
Status: ACTIVE
Contact: Site Public Contact

HI
Aiea
Hawaii Cancer Care - Savio
Status: ACTIVE
Contact: Site Public Contact
Email: info@hawaiicancercare.com

Pali Momi Medical Center
Status: ACTIVE
Contact: Site Public Contact

Queen's Cancer Center - Pearlridge
Status: ACTIVE
Contact: Site Public Contact

Straub Pearlridge Clinic
Status: ACTIVE
Contact: Site Public Contact

The Cancer Center of Hawaii-Pali Momi
Status: ACTIVE
Contact: Site Public Contact

Ewa Beach
The Queen's Medical Center - West Oahu
Status: ACTIVE
Contact: Site Public Contact
Email: rohta@queens.org

Honolulu
Hawaii Cancer Care Inc - Waterfront Plaza
Status: ACTIVE
Contact: Site Public Contact
Email: i.webster@hawaiicancercare.com

Hawaii Cancer Care Inc-Liliha
Status: ACTIVE
Contact: Site Public Contact

Hawaii Diagnostic Radiology Services LLC
Status: ACTIVE
Contact: Site Public Contact
Email: mmiyoshi@hawaiidrs.com

Island Urology
Status: TEMPORARILY_CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: virginia@cc.hawaii.edu

Kapiolani Medical Center for Women and Children
Status: ACTIVE
Contact: Site Public Contact

Kuakini Medical Center
Status: ACTIVE
Contact: Site Public Contact

Queen's Cancer Cenrer - POB I
Status: ACTIVE
Contact: Site Public Contact

Queen's Cancer Center - Kuakini
Status: ACTIVE
Contact: Site Public Contact

Queen's Medical Center
Status: ACTIVE
Contact: Site Public Contact

Straub Clinic and Hospital
Status: ACTIVE
Contact: Site Public Contact

The Cancer Center of Hawaii-Liliha
Status: ACTIVE
Contact: Site Public Contact

University of Hawaii Cancer Center
Status: ACTIVE
Contact: Site Public Contact

Kahului
Straub Medical Center - Kahului Clinic
Status: ACTIVE
Contact: Site Public Contact
Email: lori.kam@hawaiipacifichealth.org

Kailua
Castle Medical Center
Status: ACTIVE
Contact: Site Public Contact
Email: ctsucontact@westat.com

Lihue
Wilcox Memorial Hospital and Kauai Medical Clinic
Status: ACTIVE
Contact: Site Public Contact

IA
Carroll
Saint Anthony Regional Hospital
Status: ACTIVE
Contact: Site Public Contact
Email: sbenson@iora.org

Clive
Medical Oncology and Hematology Associates-West Des Moines
Status: ACTIVE
Contact: Site Public Contact

Mercy Cancer Center-West Lakes
Status: ACTIVE
Contact: Site Public Contact
Email: cancerresearch@mercydesmoines.org

Council Bluffs
Alegent Health Mercy Hospital
Status: ACTIVE
Contact: Site Public Contact
Email: ResearchInstituteInquiries@CommonSpirit.org

Heartland Oncology and Hematology LLP
Status: ACTIVE
Contact: Site Public Contact

Jennie Edmundson Memorial Hospital
Status: ACTIVE
Contact: Site Public Contact
Email: ctsucontact@westat.com

Creston
Greater Regional Medical Center
Status: ACTIVE
Contact: Site Public Contact
Email: cancerresearch@mercydesmoines.org

Davenport
Genesis Cancer Care Institute
Status: ACTIVE
Contact: Site Public Contact
Email: turnerk@genesishealth.com

Genesis Medical Center - East Campus
Status: ACTIVE
Contact: Site Public Contact
Email: turnerk@genesishealth.com

Iowa Cancer Specialists
Status: ACTIVE
Contact: Site Public Contact
Email: turnerk@genesishealth.com

Des Moines
Broadlawns Medical Center
Status: ACTIVE
Contact: Site Public Contact

Iowa Lutheran Hospital
Status: ACTIVE
Contact: Site Public Contact

Iowa Methodist Medical Center
Status: ACTIVE
Contact: Site Public Contact

Medical Oncology and Hematology Associates-Des Moines
Status: ACTIVE
Contact: Site Public Contact

Mercy Medical Center - Des Moines
Status: ACTIVE
Contact: Site Public Contact
Email: cancerresearch@mercydesmoines.org

Mission Cancer and Blood - Laurel
Status: ACTIVE
Contact: Site Public Contact

Fort Dodge
Trinity Regional Medical Center
Status: ACTIVE
Contact: Site Public Contact

West Des Moines
Mercy Medical Center-West Lakes
Status: ACTIVE
Contact: Site Public Contact
Email: cancerresearch@mercydesmoines.org

Methodist West Hospital
Status: ACTIVE
Contact: Site Public Contact

ID
Boise
Saint Alphonsus Cancer Care Center-Boise
Status: ACTIVE
Contact: Site Public Contact
Email: stephanie.couch@stjoeshealth.org

Saint Luke's Cancer Institute - Boise
Status: ACTIVE
Contact: Site Public Contact
Email: eslinget@slhs.org

Caldwell
Saint Alphonsus Cancer Care Center-Caldwell
Status: ACTIVE
Contact: Site Public Contact
Email: stephanie.couch@stjoeshealth.org

Coeur D'Alene
Kootenai Health - Coeur d'Alene
Status: ACTIVE
Contact: Site Public Contact
Email: mccinfo@mtcancer.org

Emmett
Walter Knox Memorial Hospital
Status: ACTIVE
Contact: Site Public Contact
Email: stephanie.couch@stjoeshealth.org

Fruitland
Saint Luke's Cancer Institute - Fruitland
Status: ACTIVE
Contact: Site Public Contact
Email: eslinget@slhs.org

Meridian
Idaho Urologic Institute-Meridian
Status: ACTIVE
Contact: Site Public Contact
Email: stephanie.couch@stjoeshealth.org

Saint Luke's Cancer Institute - Meridian
Status: ACTIVE
Contact: Site Public Contact
Email: eslinget@slhs.org

Nampa
Saint Alphonsus Medical Center-Nampa
Status: ACTIVE
Contact: Site Public Contact
Email: mccinfo@mtcancer.org

Saint Luke's Cancer Institute - Nampa
Status: ACTIVE
Contact: Site Public Contact
Email: eslinget@slhs.org

Post Falls
Kootenai Clinic Cancer Services - Post Falls
Status: ACTIVE
Contact: Site Public Contact
Email: mccinfo@mtcancer.org

Sandpoint
Kootenai Cancer Clinic
Status: ACTIVE
Contact: Site Public Contact
Email: mccinfo@mtcancer.org

Twin Falls
Saint Luke's Cancer Institute - Twin Falls
Status: ACTIVE
Contact: Site Public Contact
Email: eslinget@slhs.org

IL
Alton
Saint Anthony's Health
Status: ACTIVE
Contact: Site Public Contact

Aurora
Rush - Copley Medical Center
Status: ACTIVE
Contact: Site Public Contact
Email: Cancer.Research@rushcopley.com

Barrington
Advocate Good Shepherd Hospital
Status: ACTIVE
Contact: Site Public Contact

Bloomington
Illinois CancerCare-Bloomington
Status: ACTIVE
Contact: Site Public Contact
Email: andersonj@illinoiscancercare.com

Canton
Illinois CancerCare-Canton
Status: ACTIVE
Contact: Site Public Contact
Email: andersonj@illinoiscancercare.com

Carbondale
Memorial Hospital of Carbondale
Status: ACTIVE
Contact: Site Public Contact
Email: clinical.research@sih.net

Carterville
SIH Cancer Institute
Status: ACTIVE
Contact: Site Public Contact
Email: clinical.research@sih.net

Carthage
Illinois CancerCare-Carthage
Status: ACTIVE
Contact: Site Public Contact
Email: andersonj@illinoiscancercare.com

Centralia
Centralia Oncology Clinic
Status: ACTIVE
Contact: Site Public Contact
Email: morganthaler.jodi@mhsil.com

Chicago
Advocate Illinois Masonic Medical Center
Status: ACTIVE
Contact: Site Public Contact

Northwestern University
Status: ACTIVE
Contact: Site Public Contact
Email: cancer@northwestern.edu

University of Illinois
Status: ACTIVE
Contact: Site Public Contact

Crystal Lake
AMG Crystal Lake - Oncology
Status: ACTIVE
Contact: Site Public Contact
Email: advocateresearch@advocate.com

Danville
Carle on Vermilion
Status: ACTIVE
Contact: Site Public Contact
Email: Research@carle.com

Decatur
Cancer Care Specialists of Illinois - Decatur
Status: ACTIVE
Contact: Site Public Contact
Email: morganthaler.jodi@mhsil.com

Decatur Memorial Hospital
Status: ACTIVE
Contact: Site Public Contact
Email: morganthaler.jodi@mhsil.com

Dixon
Illinois CancerCare-Dixon
Status: ACTIVE
Contact: Site Public Contact

Downers Grove
Advocate Good Samaritan Hospital
Status: ACTIVE
Contact: Site Public Contact
Email: Barbara.barhamand@advocatehealth.com

Effingham
Carle Physician Group-Effingham
Status: ACTIVE
Contact: Site Public Contact
Email: Research@carle.com

Crossroads Cancer Center
Status: ACTIVE
Contact: Site Public Contact
Email: morganthaler.jodi@mhsil.com

Elgin
Advocate Sherman Hospital
Status: ACTIVE
Contact: Site Public Contact

Elk Grove Village
Ascension Alexian Brothers - Elk Grove Village
Status: ACTIVE
Contact: Site Public Contact
Email: fredianc@alexian.net

Eureka
Illinois CancerCare-Eureka
Status: ACTIVE
Contact: Site Public Contact
Email: andersonj@illinoiscancercare.com

Evanston
NorthShore University HealthSystem-Evanston Hospital
Status: ACTIVE
Contact: Site Public Contact

Galesburg
Illinois CancerCare-Galesburg
Status: ACTIVE
Contact: Site Public Contact
Email: andersonj@illinoiscancercare.com

Western Illinois Cancer Treatment Center
Status: ACTIVE
Contact: Site Public Contact

Glenview
NorthShore University HealthSystem-Glenbrook Hospital
Status: ACTIVE
Contact: Site Public Contact

Hazel Crest
Advocate South Suburban Hospital
Status: ACTIVE
Contact: Site Public Contact

Highland Park
NorthShore University HealthSystem-Highland Park Hospital
Status: ACTIVE
Contact: Site Public Contact

Kewanee
Illinois CancerCare-Kewanee Clinic
Status: ACTIVE
Contact: Site Public Contact
Email: andersonj@illinoiscancercare.com

Lake Forest
Northwestern Medicine Lake Forest Hospital
Status: ACTIVE
Contact: Site Public Contact
Email: cancertrials@northwestern.edu

Libertyville
AMG Libertyville - Oncology
Status: ACTIVE
Contact: Site Public Contact
Email: advocateresearch@advocatehealth.com

Condell Memorial Hospital
Status: ACTIVE
Contact: Site Public Contact
Email: advocateresearch@advocatehealth.com

Macomb
Illinois CancerCare-Macomb
Status: ACTIVE
Contact: Site Public Contact
Email: andersonj@illinoiscancercare.com

Mattoon
Carle Physician Group-Mattoon / Charleston
Status: ACTIVE
Contact: Site Public Contact
Email: Research@carle.com

Maywood
Loyola University Medical Center
Status: ACTIVE
Contact: Site Public Contact

Moline
Trinity Medical Center
Status: ACTIVE
Contact: Site Public Contact

Mount Vernon
Good Samaritan Regional Health Center
Status: ACTIVE
Contact: Site Public Contact

O'Fallon
Cancer Care Center of O'Fallon
Status: ACTIVE
Contact: Site Public Contact
Email: morganthaler.jodi@mhsil.com

Oak Lawn
Advocate Christ Medical Center
Status: ACTIVE
Contact: Site Public Contact

Ottawa
Illinois CancerCare-Ottawa Clinic
Status: ACTIVE
Contact: Site Public Contact
Email: andersonj@illinoiscancercare.com

Park Ridge
Advocate Lutheran General Hospital
Status: ACTIVE
Contact: Site Public Contact

Pekin
Illinois CancerCare-Pekin
Status: ACTIVE
Contact: Site Public Contact
Email: andersonj@illinoiscancercare.com

OSF Saint Francis Radiation Oncology at Pekin Cancer Treatment Center
Status: ACTIVE
Contact: Site Public Contact
Email: andersonj@illinoiscancercare.com

Peoria
Illinois CancerCare-Peoria
Status: ACTIVE
Contact: Site Public Contact
Email: andersonj@illinoiscancercare.com

Methodist Medical Center of Illinois
Status: ACTIVE
Contact: Site Public Contact
Email: andersonj@illinoiscancercare.com

OSF Saint Francis Medical Center
Status: ACTIVE
Contact: Site Public Contact
Email: andersonj@illinoiscancercare.com

OSF Saint Francis Radiation Oncology at Peoria Cancer Center
Status: ACTIVE
Contact: Site Public Contact
Email: andersonj@illinoiscancercare.com

Peru
Illinois CancerCare-Peru
Status: ACTIVE
Contact: Site Public Contact
Email: andersonj@illinoiscancercare.com

Valley Radiation Oncology
Status: ACTIVE
Contact: Site Public Contact

Princeton
Illinois CancerCare-Princeton
Status: ACTIVE
Contact: Site Public Contact
Email: andersonj@illinoiscancercare.com

Rockford
SwedishAmerican Regional Cancer Center / ACT
Status: ACTIVE
Contact: Site Public Contact
Email: cancercare@swedishamerican.org

Silvis
Genesis Cancer Center - Silvis
Status: ACTIVE
Contact: Site Public Contact
Email: turnerk@genesishealth.com

Springfield
Memorial Medical Center
Status: ACTIVE
Contact: Site Public Contact
Email: pallante.beth@mhsil.com

Southern Illinois University School of Medicine
Status: ACTIVE
Contact: Site Public Contact

Springfield Clinic
Status: ACTIVE
Contact: Site Public Contact

Swansea
Southwest Illinois Health Services LLP
Status: TEMPORARILY_CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: lynns@thecancercenter.com

Urbana
Carle Cancer Center
Status: ACTIVE
Contact: Site Public Contact
Email: Research@carle.com

The Carle Foundation Hospital
Status: ACTIVE
Contact: Site Public Contact
Email: Research@carle.com

Washington
Illinois CancerCare - Washington
Status: ACTIVE
Contact: Site Public Contact
Email: andersonj@illinoiscancercare.com

Yorkville
Rush-Copley Healthcare Center
Status: ACTIVE
Contact: Site Public Contact
Email: Cancer.Research@rushcopley.com

IN
Muncie
IU Health Ball Memorial Hospital
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact

Richmond
Reid Health
Status: ACTIVE
Contact: Site Public Contact
Email: clinical.trials@daytonncorp.org

KS
Garden City
Central Care Cancer Center - Garden City
Status: ACTIVE
Contact: Site Public Contact
Email: aroland@kccop.org

Great Bend
Central Care Cancer Center - Great Bend
Status: ACTIVE
Contact: Site Public Contact
Email: aroland@kccop.org

Topeka
Cotton O'Neil Cancer Center / Stormont Vail Health
Status: ACTIVE
Contact: Site Public Contact

KY
Bardstown
Flaget Memorial Hospital
Status: ACTIVE
Contact: Site Public Contact
Email: ResearchInstituteInquiries@CommonSpirit.org

Corbin
Commonwealth Cancer Center-Corbin
Status: ACTIVE
Contact: Site Public Contact
Email: ResearchInstituteInquiries@CommonSpirit.org

Lexington
Saint Joseph Hospital East
Status: ACTIVE
Contact: Site Public Contact
Email: ResearchInstituteInquiries@CommonSpirit.org

Saint Joseph Radiation Oncology Resource Center
Status: ACTIVE
Contact: Site Public Contact
Email: ResearchInstituteInquiries@CommonSpirit.org

London
Saint Joseph London
Status: ACTIVE
Contact: Site Public Contact
Email: ResearchInstituteInquiries@CommonSpirit.org

Louisville
Jewish Hospital
Status: TEMPORARILY_CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: ResearchInstituteInquiries@CommonSpirit.org

Saints Mary and Elizabeth Hospital
Status: TEMPORARILY_CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: ResearchInstituteInquiries@CommonSpirit.org

UofL Health Medical Center Northeast
Status: TEMPORARILY_CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: ctoinfo@louisville.edu

Shepherdsville
Jewish Hospital Medical Center South
Status: TEMPORARILY_CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: ResearchInstituteInquiries@CommonSpirit.org

LA
Baton Rouge
Ochsner High Grove
Status: ACTIVE
Contact: Site Public Contact
Email: Camielle.beck@ochsner.org

New Orleans
Ochsner Medical Center Jefferson
Status: ACTIVE
Contact: Site Public Contact
Email: Elisemarie.curry@ochsner.org

Shreveport
CHRISTUS Highland Medical Center
Status: ACTIVE
Contact: Site Public Contact
Email: Nancy.hassan@christushealth.org

MA
Beverly
Beverly Hospital
Status: ACTIVE
Contact: Site Public Contact

Boston
Boston Medical Center
Status: ACTIVE
Contact: Site Public Contact

Burlington
Lahey Hospital and Medical Center
Status: ACTIVE
Contact: Site Public Contact
Email: cancerclinicaltrials@lahey.org

Gloucester
Addison Gilbert Hospital
Status: ACTIVE
Contact: Site Public Contact

Peabody
Lahey Medical Center-Peabody
Status: ACTIVE
Contact: Site Public Contact
Email: cancerclinicaltrials@lahey.org

Plymouth
Beth Israel Deaconess Hospital-Plymouth
Status: ACTIVE
Contact: Site Public Contact
Email: cancerinfo@jordanhospital.org

Springfield
Baystate Medical Center
Status: ACTIVE
Contact: Site Public Contact
Email: tamara.wrenn@baystatehealth.org

Mercy Medical Center
Status: TEMPORARILY_CLOSED_TO_ACCRUAL
Contact: Site Public Contact

Winchester
Winchester Hospital
Status: ACTIVE
Contact: Site Public Contact
Email: ctsucontact@westat.com

Worcester
UMass Memorial Medical Center - University Campus
Status: ACTIVE
Contact: Site Public Contact
Email: cancer.research@umassmed.edu

MD
Baltimore
Greater Baltimore Medical Center
Status: ACTIVE
Contact: Site Public Contact

Saint Agnes Hospital
Status: ACTIVE
Contact: Site Public Contact

Bel Air
UM Upper Chesapeake Medical Center
Status: TEMPORARILY_CLOSED_TO_ACCRUAL
Contact: Site Public Contact

Easton
University of Maryland Shore Medical Center at Easton
Status: TEMPORARILY_CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: Christina.weisenborn@umm.edu

ME
Bangor
Eastern Maine Medical Center
Status: ACTIVE
Contact: Site Public Contact

Bath
MaineHealth Coastal Cancer Treatment Center
Status: ACTIVE
Contact: Site Public Contact
Email: ctsucontact@westat.com

Biddeford
MaineHealth / SMHC Cancer Care and Blood Disorders-Biddeford
Status: ACTIVE
Contact: Site Public Contact
Email: LLemire@mmc.org

Brewer
Lafayette Family Cancer Center-EMMC
Status: ACTIVE
Contact: Site Public Contact

Portland
Maine Medical Center-Bramhall Campus
Status: ACTIVE
Contact: Site Public Contact

Sanford
MaineHealth / SMHC Cancer Care and Blood Disorders-Sanford
Status: ACTIVE
Contact: Site Public Contact
Email: LLemire@mmc.org

MaineHealth Cancer Care Center of York County
Status: ACTIVE
Contact: Site Public Contact

Scarborough
Maine Medical Center- Scarborough Campus
Status: ACTIVE
Contact: Site Public Contact
Email: wrighd@mmc.org

South Portland
Maine Medical Partners - South Portland
Status: ACTIVE
Contact: Site Public Contact
Email: ClinicalResearch@mmc.org

MI
Ann Arbor
Saint Joseph Mercy Hospital
Status: ACTIVE
Contact: Site Public Contact
Email: MCRCwebsitecontactform@stjoeshealth.org

Battle Creek
Bronson Battle Creek
Status: ACTIVE
Contact: Site Public Contact
Email: crcwm-regulatory@crcwm.org

Brighton
Saint Joseph Mercy Brighton
Status: ACTIVE
Contact: Site Public Contact
Email: MCRCwebsitecontactform@stjoeshealth.org

Trinity Health IHA Medical Group Hematology Oncology - Brighton
Status: ACTIVE
Contact: Site Public Contact
Email: MCRCwebsitecontactform@stjoeshealth.org

Canton
Saint Joseph Mercy Canton
Status: ACTIVE
Contact: Site Public Contact
Email: MCRCwebsitecontactform@stjoeshealth.org

Trinity Health IHA Medical Group Hematology Oncology - Canton
Status: ACTIVE
Contact: Site Public Contact
Email: MCRCwebsitecontactform@stjoeshealth.org

Caro
Caro Cancer Center
Status: ACTIVE
Contact: Site Public Contact
Email: lori.srebinski@ascension.org

Chelsea
Saint Joseph Mercy Chelsea
Status: ACTIVE
Contact: Site Public Contact
Email: MCRCwebsitecontactform@stjoeshealth.org

Trinity Health IHA Medical Group Hematology Oncology - Chelsea Hospital
Status: ACTIVE
Contact: Site Public Contact
Email: MCRCwebsitecontactform@stjoeshealth.org

Clarkston
GenesisCare USA - Clarkston
Status: ACTIVE
Contact: Site Public Contact
Email: Rudi.Ross@usa.genesiscare.com

Hematology Oncology Consultants-Clarkston
Status: ACTIVE
Contact: Site Public Contact
Email: MCRCwebsitecontactform@stjoeshealth.org

Newland Medical Associates-Clarkston
Status: ACTIVE
Contact: Site Public Contact
Email: MCRCwebsitecontactform@stjoeshealth.org

Detroit
Ascension Saint John Hospital
Status: ACTIVE
Contact: Site Public Contact
Email: karen.forman@ascension.org

East China
Great Lakes Cancer Management Specialists-Doctors Park
Status: ACTIVE
Contact: Site Public Contact
Email: karen.forman@ascension.org

Farmington Hills
GenesisCare USA - Farmington Hills
Status: ACTIVE
Contact: Site Public Contact
Email: Rudi.Ross@usa.genesiscare.com

Flint
Genesee Cancer and Blood Disease Treatment Center
Status: ACTIVE
Contact: Site Public Contact
Email: wstrong@ghci.org

Genesee Hematology Oncology PC
Status: ACTIVE
Contact: Site Public Contact
Email: wstrong@ghci.org

Genesys Hurley Cancer Institute
Status: ACTIVE
Contact: Site Public Contact
Email: wstrong@ghci.org

Hurley Medical Center
Status: ACTIVE
Contact: Site Public Contact
Email: wstrong@ghci.org

Grand Rapids
Helen DeVos Children's Hospital at Spectrum Health
Status: ACTIVE
Contact: Site Public Contact
Email: crcwm-regulatory@crcwm.org

Mercy Health Saint Mary's
Status: ACTIVE
Contact: Site Public Contact
Email: crcwm-regulatory@crcwm.org

Spectrum Health at Butterworth Campus
Status: ACTIVE
Contact: Site Public Contact
Email: crcwm-regulatory@crcwm.org

Grosse Pointe Woods
Academic Hematology Oncology Specialists
Status: ACTIVE
Contact: Site Public Contact
Email: karen.forman@ascension.org

Great Lakes Cancer Management Specialists-Van Elslander Cancer Center
Status: ACTIVE
Contact: Site Public Contact
Email: karen.forman@ascension.org

Michigan Breast Specialists-Grosse Pointe Woods
Status: ACTIVE
Contact: Site Public Contact
Email: karen.forman@ascension.org

Kalamazoo
Ascension Borgess Cancer Center
Status: ACTIVE
Contact: Site Public Contact
Email: crcwm-regulatory@crcwm.org

Borgess Medical Center
Status: ACTIVE
Contact: Site Public Contact
Email: crcwm-regulatory@crcwm.org

Bronson Methodist Hospital
Status: ACTIVE
Contact: Site Public Contact
Email: crcwm-regulatory@crcwm.org

West Michigan Cancer Center
Status: ACTIVE
Contact: Site Public Contact
Email: crcwm-regulatory@crcwm.org

Lansing
Sparrow Hospital
Status: ACTIVE
Contact: Site Public Contact

Livonia
Hope Cancer Clinic
Status: TEMPORARILY_CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: stephanie.couch@stjoeshealth.org

Trinity Health Saint Mary Mercy Livonia Hospital
Status: ACTIVE
Contact: Site Public Contact
Email: MCRCwebsitecontactform@stjoeshealth.org

Macomb
GenesisCare USA - Macomb
Status: ACTIVE
Contact: Site Public Contact
Email: Rudi.Ross@usa.genesiscare.com

Macomb Township
Great Lakes Cancer Management Specialists-Macomb Medical Campus
Status: ACTIVE
Contact: Site Public Contact
Email: karen.forman@ascension.org

Michigan Breast Specialists-Macomb Township
Status: ACTIVE
Contact: Site Public Contact
Email: karen.forman@ascension.org

Madison Heights
GenesisCare USA - Madison Heights
Status: ACTIVE
Contact: Site Public Contact
Email: Rudi.Ross@usa.genesiscare.com

Marlette
Saint Mary's Oncology / Hematology Associates of Marlette
Status: ACTIVE
Contact: Site Public Contact
Email: lori.srebinski@ascension.org

Muskegon
Mercy Health Mercy Campus
Status: ACTIVE
Contact: Site Public Contact
Email: crcwm-regulatory@crcwm.org

Niles
Lakeland Hospital Niles
Status: ACTIVE
Contact: Site Public Contact

Norton Shores
Cancer and Hematology Centers of Western Michigan - Norton Shores
Status: ACTIVE
Contact: Site Public Contact
Email: connie.szczepanek@crcwm.org

Novi
Ascension Providence Hospitals - Novi
Status: ACTIVE
Contact: Site Public Contact
Email: karen.fife@ascension.org

Pontiac
21st Century Oncology-Pontiac
Status: ACTIVE
Contact: Site Public Contact
Email: stephanie.couch@stjoeshealth.org

Hope Cancer Center
Status: ACTIVE
Contact: Site Public Contact
Email: MCRCwebsitecontactform@stjoeshealth.org

Newland Medical Associates-Pontiac
Status: ACTIVE
Contact: Site Public Contact
Email: MCRCwebsitecontactform@stjoeshealth.org

Saint Joseph Mercy Oakland
Status: ACTIVE
Contact: Site Public Contact
Email: MCRCwebsitecontactform@stjoeshealth.org

Reed City
Spectrum Health Reed City Hospital
Status: ACTIVE
Contact: Site Public Contact
Email: crcwm-regulatory@crcwm.org

Rochester Hills
Great Lakes Cancer Management Specialists-Rochester Hills
Status: TEMPORARILY_CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: stephanie.couch@stjoeshealth.org

Saginaw
Ascension Saint Mary's Hospital
Status: ACTIVE
Contact: Site Public Contact
Email: lori.srebinski@ascension.org

Oncology Hematology Associates of Saginaw Valley PC
Status: ACTIVE
Contact: Site Public Contact
Email: lori.srebinski@ascension.org

Saint Joseph
Lakeland Medical Center Saint Joseph
Status: ACTIVE
Contact: Site Public Contact
Email: crcwm-regulatory@crcwm.org

Marie Yeager Cancer Center
Status: ACTIVE
Contact: Site Public Contact
Email: crcwm-regulatory@crcwm.org

Southfield
Ascension Providence Hospitals - Southfield
Status: ACTIVE
Contact: Site Public Contact
Email: karen.fife@ascension.org

Sterling Heights
Bhadresh Nayak MD PC-Sterling Heights
Status: ACTIVE
Contact: Site Public Contact
Email: karen.forman@ascension.org

Tawas City
Ascension Saint Joseph Hospital
Status: ACTIVE
Contact: Site Public Contact
Email: lori.srebinski@ascension.org

Traverse City
Munson Medical Center
Status: ACTIVE
Contact: Site Public Contact
Email: crcwm-regulatory@crcwm.org

Troy
GenesisCare USA - Troy
Status: ACTIVE
Contact: Site Public Contact
Email: Rudi.Ross@usa.genesiscare.com

Warren
Advanced Breast Care Center PLLC
Status: ACTIVE
Contact: Site Public Contact
Email: karen.forman@ascension.org

Great Lakes Cancer Management Specialists-Macomb Professional Building
Status: ACTIVE
Contact: Site Public Contact
Email: karen.forman@ascension.org

Macomb Hematology Oncology PC
Status: ACTIVE
Contact: Site Public Contact
Email: karen.forman@ascension.org

Michigan Breast Specialists-Warren
Status: ACTIVE
Contact: Site Public Contact
Email: karen.forman@ascension.org

Saint John Macomb-Oakland Hospital
Status: ACTIVE
Contact: Site Public Contact
Email: karen.forman@ascension.org

West Branch
Saint Mary's Oncology / Hematology Associates of West Branch
Status: ACTIVE
Contact: Site Public Contact
Email: lori.srebinski@ascension.org

Wyoming
Metro Health Hospital
Status: ACTIVE
Contact: Site Public Contact
Email: crcwm-regulatory@crcwm.org

Ypsilanti
Huron Gastroenterology PC
Status: ACTIVE
Contact: Site Public Contact
Email: MCRCwebsitecontactform@stjoeshealth.org

Trinity Health IHA Medical Group Hematology Oncology Ann Arbor Campus
Status: ACTIVE
Contact: Site Public Contact
Email: MCRCwebsitecontactform@stjoeshealth.org

MN
Aitkin
Riverwood Healthcare Center
Status: ACTIVE
Contact: Site Public Contact
Email: CancerTrials@EssentiaHealth.org

Baxter
Essentia Health - Baxter Clinic
Status: ACTIVE
Contact: Site Public Contact

Bemidji
Sanford Joe Lueken Cancer Center
Status: ACTIVE
Contact: Site Public Contact
Email: OncologyClinicalTrialsFargo@sanfordhealth.org

Brainerd
Essentia Health Saint Joseph's Medical Center
Status: ACTIVE
Contact: Site Public Contact
Email: CancerTrials@EssentiaHealth.org

Burnsville
Fairview Ridges Hospital
Status: ACTIVE
Contact: Site Public Contact
Email: mmcorc@healthpartners.com

Minnesota Oncology - Burnsville
Status: ACTIVE
Contact: Site Public Contact
Email: mmcorc@healthpartners.com

Cambridge
Cambridge Medical Center
Status: ACTIVE
Contact: Site Public Contact
Email: mmcorc@healthpartners.com

Coon Rapids
Mercy Hospital
Status: ACTIVE
Contact: Site Public Contact
Email: mmcorc@healthpartners.com

Deer River
Essentia Health - Deer River Clinic
Status: ACTIVE
Contact: Site Public Contact
Email: CancerTrials@EssentiaHealth.org

Detroit Lakes
Essentia Health Saint Mary's - Detroit Lakes Clinic
Status: ACTIVE
Contact: Site Public Contact
Email: CancerTrials@EssentiaHealth.org

Duluth
Essentia Health Cancer Center
Status: ACTIVE
Contact: Site Public Contact
Email: CancerTrials@EssentiaHealth.org

Essentia Health Saint Mary's Medical Center
Status: ACTIVE
Contact: Site Public Contact
Email: CancerTrials@EssentiaHealth.org

Miller-Dwan Hospital
Status: ACTIVE
Contact: Site Public Contact
Email: CancerTrials@EssentiaHealth.org

Edina
Fairview Southdale Hospital
Status: ACTIVE
Contact: Site Public Contact
Email: mmcorc@healthpartners.com

Ely
Essentia Health - Ely Clinic
Status: ACTIVE
Contact: Site Public Contact

Fergus Falls
Lake Region Healthcare Corporation-Cancer Care
Status: TEMPORARILY_CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: CancerTrials@EssentiaHealth.org

Fosston
Essentia Health - Fosston
Status: ACTIVE
Contact: Site Public Contact
Email: CancerTrials@EssentiaHealth.org

Fridley
Unity Hospital
Status: ACTIVE
Contact: Site Public Contact
Email: mmcorc@healthpartners.com

Hibbing
Essentia Health Hibbing Clinic
Status: ACTIVE
Contact: Site Public Contact

International Falls
Essentia Health - International Falls Clinic
Status: ACTIVE
Contact: Site Public Contact

Maple Grove
Fairview Clinics and Surgery Center Maple Grove
Status: ACTIVE
Contact: Site Public Contact
Email: mmcorc@healthpartners.com

Maplewood
Minnesota Oncology Hematology PA-Maplewood
Status: ACTIVE
Contact: Site Public Contact
Email: mmcorc@healthpartners.com

Saint John's Hospital - Healtheast
Status: ACTIVE
Contact: Site Public Contact
Email: mmcorc@healthpartners.com

Minneapolis
Abbott-Northwestern Hospital
Status: ACTIVE
Contact: Site Public Contact
Email: mmcorc@healthpartners.com

Health Partners Inc
Status: ACTIVE
Contact: Site Public Contact
Email: mmcorc@healthpartners.com

Hennepin County Medical Center
Status: ACTIVE
Contact: Site Public Contact
Email: mmcorc@healthpartners.com

Monticello
Monticello Cancer Center
Status: ACTIVE
Contact: Site Public Contact
Email: mmcorc@healthpartners.com

Moose Lake
Essentia Health - Moose Lake Clinic
Status: ACTIVE
Contact: Site Public Contact

New Ulm
New Ulm Medical Center
Status: ACTIVE
Contact: Site Public Contact
Email: mmcorc@healthpartners.com

Park Rapids
Essentia Health - Park Rapids
Status: ACTIVE
Contact: Site Public Contact
Email: CancerTrials@EssentiaHealth.org

Princeton
Fairview Northland Medical Center
Status: ACTIVE
Contact: Site Public Contact
Email: mmcorc@healthpartners.com

Robbinsdale
North Memorial Medical Health Center
Status: ACTIVE
Contact: Site Public Contact
Email: mmcorc@healthpartners.com

Saint Louis Park
Park Nicollet Clinic - Saint Louis Park
Status: ACTIVE
Contact: Site Public Contact
Email: mmcorc@healthpartners.com

Saint Paul
Regions Hospital
Status: ACTIVE
Contact: Site Public Contact
Email: mmcorc@healthpartners.com

United Hospital
Status: ACTIVE
Contact: Site Public Contact
Email: mmcorc@healthpartners.com

Sandstone
Essentia Health Sandstone
Status: ACTIVE
Contact: Site Public Contact
Email: CancerTrials@EssentiaHealth.org

Shakopee
Saint Francis Regional Medical Center
Status: ACTIVE
Contact: Site Public Contact
Email: mmcorc@healthpartners.com

Stillwater
Lakeview Hospital
Status: ACTIVE
Contact: Site Public Contact
Email: mmcorc@healthpartners.com

Thief River Falls
Sanford Thief River Falls Medical Center
Status: ACTIVE
Contact: Site Public Contact

Virginia
Essentia Health Virginia Clinic
Status: ACTIVE
Contact: Site Public Contact
Email: CancerTrials@EssentiaHealth.org

Waconia
Ridgeview Medical Center
Status: ACTIVE
Contact: Site Public Contact
Email: mmcorc@healthpartners.com

Willmar
Rice Memorial Hospital
Status: ACTIVE
Contact: Site Public Contact
Email: mmcorc@healthpartners.com

Woodbury
Minnesota Oncology Hematology PA-Woodbury
Status: ACTIVE
Contact: Site Public Contact
Email: mmcorc@healthpartners.com

Wyoming
Fairview Lakes Medical Center
Status: ACTIVE
Contact: Site Public Contact
Email: mmcorc@healthpartners.com

MO
Ballwin
Saint Louis Cancer and Breast Institute-Ballwin
Status: ACTIVE
Contact: Site Public Contact

Bolivar
Central Care Cancer Center - Bolivar
Status: ACTIVE
Contact: Site Public Contact
Email: aroland@kccop.org

Branson
Cox Cancer Center Branson
Status: ACTIVE
Contact: Site Public Contact

Cape Girardeau
Saint Francis Medical Center
Status: ACTIVE
Contact: Site Public Contact
Email: sfmc@sfmc.net

Southeast Cancer Center
Status: ACTIVE
Contact: Site Public Contact

Farmington
Parkland Health Center - Farmington
Status: ACTIVE
Contact: Site Public Contact

Jefferson City
Capital Region Southwest Campus
Status: ACTIVE
Contact: Site Public Contact
Email: swooden@mail.crmc.org

Joplin
Freeman Health System
Status: ACTIVE
Contact: Site Public Contact
Email: LJCrockett@freemanhealth.com

Mercy Hospital Joplin
Status: ACTIVE
Contact: Site Public Contact
Email: esmeralda.carrillo@mercy.net

Rolla
Delbert Day Cancer Institute at PCRMC
Status: ACTIVE
Contact: Site Public Contact
Email: research@phelpshealth.org

Mercy Clinic-Rolla-Cancer and Hematology
Status: ACTIVE
Contact: Site Public Contact

Saint Joseph
Heartland Regional Medical Center
Status: ACTIVE
Contact: Site Public Contact
Email: linda.schumacher@mymlc.com

Saint Louis
Mercy Hospital Saint Louis
Status: ACTIVE
Contact: Site Public Contact

Mercy Hospital South
Status: ACTIVE
Contact: Site Public Contact
Email: janet.lesko@mercy.net

Missouri Baptist Medical Center
Status: ACTIVE
Contact: Site Public Contact

Saint Louis Cancer and Breast Institute-South City
Status: ACTIVE
Contact: Site Public Contact

Sainte Genevieve
Sainte Genevieve County Memorial Hospital
Status: ACTIVE
Contact: Site Public Contact

Springfield
CoxHealth South Hospital
Status: ACTIVE
Contact: Site Public Contact

Mercy Hospital Springfield
Status: ACTIVE
Contact: Site Public Contact

Sullivan
Missouri Baptist Sullivan Hospital
Status: ACTIVE
Contact: Site Public Contact

Sunset Hills
Missouri Baptist Outpatient Center-Sunset Hills
Status: ACTIVE
Contact: Site Public Contact

Washington
Mercy Hospital Washington
Status: ACTIVE
Contact: Site Public Contact

MS
Columbus
Baptist Memorial Hospital and Cancer Center-Golden Triangle
Status: ACTIVE
Contact: Site Public Contact
Email: BCCclintrials@bmhcc.org

Grenada
Baptist Cancer Center-Grenada
Status: ACTIVE
Contact: Site Public Contact
Email: BCCclintrials@bmhcc.org

Hattiesburg
Forrest General Hospital / Cancer Center
Status: ACTIVE
Contact: Site Public Contact
Email: tmcbeth@forrestgeneral.com

Hattiesburg Clinic - Hematology / Oncology Clinic
Status: ACTIVE
Contact: Site Public Contact
Email: tmcbeth@forrestgeneral.com

Jackson
University of Mississippi Medical Center
Status: ACTIVE
Contact: Site Public Contact

New Albany
Baptist Memorial Hospital and Cancer Center-Union County
Status: ACTIVE
Contact: Site Public Contact
Email: BCCclintrials@bmhcc.org

Oxford
Baptist Memorial Hospital and Cancer Center-Oxford
Status: ACTIVE
Contact: Site Public Contact
Email: BCCclintrials@bmhcc.org

Southhaven
Baptist Memorial Hospital and Cancer Center-Desoto
Status: ACTIVE
Contact: Site Public Contact
Email: BCCclintrials@bmhcc.org

MT
Anaconda
Community Hospital of Anaconda
Status: ACTIVE
Contact: Site Public Contact
Email: mccinfo@mtcancer.org

Billings
Billings Clinic Cancer Center
Status: ACTIVE
Contact: Site Public Contact
Email: research@billingsclinic.org

Saint Vincent Frontier Cancer Center
Status: TEMPORARILY_CLOSED_TO_ACCRUAL
Contact: Site Public Contact

Saint Vincent Healthcare
Status: TEMPORARILY_CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: mccinfo@mtcancer.org

Bozeman
Bozeman Deaconess Hospital
Status: ACTIVE
Contact: Site Public Contact
Email: mccinfo@mtcancer.org

Butte
Saint James Community Hospital and Cancer Treatment Center
Status: TEMPORARILY_CLOSED_TO_ACCRUAL
Contact: Site Public Contact

Great Falls
Benefis Healthcare- Sletten Cancer Institute
Status: ACTIVE
Contact: Site Public Contact
Email: mccinfo@mtcancer.org

Great Falls Clinic
Status: ACTIVE
Contact: Site Public Contact
Email: mccinfo@mtcancer.org

Kalispell
Kalispell Regional Medical Center
Status: ACTIVE
Contact: Site Public Contact
Email: mccinfo@mtcancer.org

Missoula
Community Medical Hospital
Status: ACTIVE
Contact: Site Public Contact
Email: mccinfo@mtcancer.org

Saint Patrick Hospital - Community Hospital
Status: ACTIVE
Contact: Site Public Contact
Email: amy.hanneman@providence.org

NC
Greenville
East Carolina University
Status: ACTIVE
Contact: Site Public Contact
Email: eubankss@ecu.edu

Hendersonville
Margaret R Pardee Memorial Hospital
Status: ACTIVE
Contact: Site Public Contact
Email: karen.morris@unchealth.unc.edu

Kenansville
Vidant Oncology-Kenansville
Status: ACTIVE
Contact: Site Public Contact
Email: Carla.Zimmerman@vidanthealth.com

Kinston
Vidant Oncology-Kinston
Status: ACTIVE
Contact: Site Public Contact
Email: Carla.Zimmerman@vidanthealth.com

New Bern
CarolinaEast Medical Center
Status: ACTIVE
Contact: Site Public Contact
Email: lharrison@carolinaeasthealth.com

Pinehurst
FirstHealth of the Carolinas-Moore Regional Hospital
Status: ACTIVE
Contact: Site Public Contact
Email: jcwilliams@firsthealth.org

Richlands
Vidant Oncology-Richlands
Status: ACTIVE
Contact: Site Public Contact
Email: Carla.Zimmerman@vidanthealth.com

ND
Bismarck
Sanford Bismarck Medical Center
Status: ACTIVE
Contact: Site Public Contact
Email: OncologyClinicalTrialsFargo@sanfordhealth.org

Fargo
Essentia Health Cancer Center-South University Clinic
Status: ACTIVE
Contact: Site Public Contact
Email: CancerTrials@EssentiaHealth.org

Sanford Broadway Medical Center
Status: ACTIVE
Contact: Site Public Contact
Email: OncologyClinicalTrialsFargo@sanfordhealth.org

Sanford Medical Center Fargo
Status: ACTIVE
Contact: Site Public Contact

Sanford Roger Maris Cancer Center
Status: ACTIVE
Contact: Site Public Contact
Email: OncologyClinicalTrialsFargo@sanfordhealth.org

Sanford South University Medical Center
Status: ACTIVE
Contact: Site Public Contact

Southpointe-Sanford Medical Center Fargo
Status: ACTIVE
Contact: Site Public Contact

Jamestown
Essentia Health - Jamestown Clinic
Status: ACTIVE
Contact: Site Public Contact
Email: CancerTrials@EssentiaHealth.org

NE
Grand Island
CHI Health Saint Francis
Status: ACTIVE
Contact: Site Public Contact

Kearney
CHI Health Good Samaritan
Status: ACTIVE
Contact: Site Public Contact
Email: ResearchInstituteInquiries@CommonSpirit.org

Lincoln
Cancer Partners of Nebraska - Pine Lake
Status: ACTIVE
Contact: Site Public Contact
Email: research@cancerpartners.com

Saint Elizabeth Regional Medical Center
Status: ACTIVE
Contact: Site Public Contact
Email: ResearchInstituteInquiries@CommonSpirit.org

Southeast Nebraska Cancer Center - 68th Street Place
Status: ACTIVE
Contact: Site Public Contact
Email: research@cancerpartners.com

Omaha
Alegent Health Bergan Mercy Medical Center
Status: ACTIVE
Contact: Site Public Contact
Email: ResearchInstituteInquiries@CommonSpirit.org

Alegent Health Immanuel Medical Center
Status: ACTIVE
Contact: Site Public Contact
Email: ResearchInstituteInquiries@CommonSpirit.org

Alegent Health Lakeside Hospital
Status: ACTIVE
Contact: Site Public Contact
Email: ResearchInstituteInquiries@CommonSpirit.org

Creighton University Medical Center
Status: ACTIVE
Contact: Site Public Contact
Email: ResearchInstituteInquiries@CommonSpirit.org

Nebraska Methodist Hospital
Status: ACTIVE
Contact: Site Public Contact

Oncology Associates PC
Status: ACTIVE
Contact: Site Public Contact
Email: info@oa-oc.com

Papillion
Midlands Community Hospital
Status: ACTIVE
Contact: Site Public Contact
Email: ResearchInstituteInquiries@CommonSpirit.org

NH
Concord
New Hampshire Oncology Hematology PA-Concord
Status: ACTIVE
Contact: Site Public Contact

Lebanon
Dartmouth Hitchcock Medical Center
Status: ACTIVE
Contact: Site Public Contact
Email: cancer.research.nurse@dartmouth.edu

Manchester
Elliot Hospital
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact

Solinsky Center for Cancer Care
Status: ACTIVE
Contact: Site Public Contact

NJ
Hamilton
The Cancer Institute of New Jersey Hamilton
Status: ACTIVE
Contact: Site Public Contact

Jersey City
Jersey City Medical Center
Status: ACTIVE
Contact: Site Public Contact
Email: ecog.rss@jimmy.harvard.edu

Lakewood
Monmouth Medical Center Southern Campus
Status: ACTIVE
Contact: Site Public Contact
Email: mary.danish@rwjbh.org

Livingston
Saint Barnabas Medical Center
Status: ACTIVE
Contact: Site Public Contact
Email: joanne.loeb@rwjbh.org

Long Branch
Monmouth Medical Center
Status: ACTIVE
Contact: Site Public Contact
Email: mary.danish@rwjbh.org

Moorestown
Virtua Samson Cancer Center
Status: ACTIVE
Contact: Site Public Contact

Mount Holly
Virtua Memorial
Status: ACTIVE
Contact: Site Public Contact

New Brunswick
Rutgers Cancer Institute of New Jersey
Status: ACTIVE
Contact: Site Public Contact

Somerville
Robert Wood Johnson University Hospital Somerset
Status: ACTIVE
Contact: Site Public Contact
Email: Siby.Varughese@rwjbh.org

Toms River
Community Medical Center
Status: ACTIVE
Contact: Site Public Contact
Email: Lennette.Gonzales@rwjbh.org

Voorhees
Virtua Voorhees
Status: ACTIVE
Contact: Site Public Contact

NM
Albuquerque
University of New Mexico Cancer Center
Status: ACTIVE
Contact: Site Public Contact
Email: LByatt@nmcca.org

NV
Carson City
Carson Tahoe Regional Medical Center
Status: ACTIVE
Contact: Site Public Contact
Email: research@sncrf.org

Henderson
Cancer and Blood Specialists-Henderson
Status: ACTIVE
Contact: Site Public Contact
Email: research@sncrf.org

Comprehensive Cancer Centers of Nevada - Henderson
Status: ACTIVE
Contact: Site Public Contact
Email: research@sncrf.org

Comprehensive Cancer Centers of Nevada-Horizon Ridge
Status: ACTIVE
Contact: Site Public Contact
Email: research@sncrf.org

Comprehensive Cancer Centers of Nevada-Southeast Henderson
Status: ACTIVE
Contact: Site Public Contact
Email: research@sncrf.org

GenesisCare USA - Henderson
Status: ACTIVE
Contact: Site Public Contact
Email: research@sncrf.org

Las Vegas Cancer Center-Henderson
Status: ACTIVE
Contact: Site Public Contact
Email: research@sncrf.org

Las Vegas Urology - Green Valley
Status: ACTIVE
Contact: Site Public Contact
Email: research@sncrf.org

Las Vegas Urology - Pebble
Status: ACTIVE
Contact: Site Public Contact
Email: research@sncrf.org

OptumCare Cancer Care at Seven Hills
Status: ACTIVE
Contact: Site Public Contact
Email: research@sncrf.org

Urology Specialists of Nevada - Green Valley
Status: ACTIVE
Contact: Site Public Contact
Email: research@sncrf.org

Las Vegas
Alliance for Childhood Diseases / Cure 4 the Kids Foundation
Status: ACTIVE
Contact: Site Public Contact
Email: research@sncrf.org

Ann M Wierman MD LTD
Status: ACTIVE
Contact: Site Public Contact
Email: research@sncrf.org

Comprehensive Cancer Centers of Nevada
Status: ACTIVE
Contact: Site Public Contact
Email: research@sncrf.org

Comprehensive Cancer Centers of Nevada - Central Valley
Status: ACTIVE
Contact: Site Public Contact
Email: research@sncrf.org

Comprehensive Cancer Centers of Nevada - Northwest
Status: ACTIVE
Contact: Site Public Contact
Email: research@sncrf.org

Comprehensive Cancer Centers of Nevada - Town Center
Status: ACTIVE
Contact: Site Public Contact
Email: research@sncrf.org

Comprehensive Cancer Centers of Nevada-Summerlin
Status: ACTIVE
Contact: Site Public Contact
Email: research@sncrf.org

Desert West Surgery
Status: TEMPORARILY_CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: research@sncrf.org

GenesisCare USA - Fort Apache
Status: ACTIVE
Contact: Site Public Contact
Email: research@sncrf.org

GenesisCare USA - Las Vegas
Status: ACTIVE
Contact: Site Public Contact
Email: research@sncrf.org

GenesisCare USA - Vegas Tenaya
Status: ACTIVE
Contact: Site Public Contact
Email: research@sncrf.org

HealthCare Partners Medical Group Oncology / Hematology-Centennial Hills
Status: TEMPORARILY_CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: research@sncrf.org

HealthCare Partners Medical Group Oncology / Hematology-Maryland Parkway
Status: TEMPORARILY_CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: research@sncrf.org

HealthCare Partners Medical Group Oncology / Hematology-San Martin
Status: TEMPORARILY_CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: research@sncrf.org

HealthCare Partners Medical Group Oncology / Hematology-Tenaya
Status: TEMPORARILY_CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: research@sncrf.org

Hope Cancer Care of Nevada
Status: ACTIVE
Contact: Site Public Contact
Email: research@sncrf.org

Las Vegas Cancer Center-Medical Center
Status: ACTIVE
Contact: Site Public Contact
Email: research@sncrf.org

Las Vegas Prostate Cancer Center
Status: ACTIVE
Contact: Site Public Contact
Email: research@sncrf.org

Las Vegas Urology - Cathedral Rock
Status: ACTIVE
Contact: Site Public Contact
Email: research@sncrf.org

Las Vegas Urology - Pecos
Status: ACTIVE
Contact: Site Public Contact
Email: research@sncrf.org

Las Vegas Urology - Smoke Ranch
Status: ACTIVE
Contact: Site Public Contact
Email: research@smcrf.org

Las Vegas Urology - Sunset
Status: ACTIVE
Contact: Site Public Contact
Email: research@sncrf.org

OptumCare Cancer Care at Charleston
Status: ACTIVE
Contact: Site Public Contact
Email: research@sncrf.org

OptumCare Cancer Care at Fort Apache
Status: ACTIVE
Contact: Site Public Contact
Email: research@sncrf.org

OptumCare Cancer Care at MountainView
Status: ACTIVE
Contact: Site Public Contact
Email: research@sncrf.org

Radiation Oncology Centers of Nevada Central
Status: ACTIVE
Contact: Site Public Contact
Email: research@sncrf.org

Radiation Oncology Centers of Nevada Southeast
Status: ACTIVE
Contact: Site Public Contact
Email: research@sncrf.org

Summerlin Hospital Medical Center
Status: ACTIVE
Contact: Site Public Contact
Email: research@sncrf.org

Sunrise Hospital and Medical Center
Status: ACTIVE
Contact: Site Public Contact
Email: research@sncrf.org

University Cancer Center
Status: ACTIVE
Contact: Site Public Contact
Email: research@sncrf.org

University Medical Center of Southern Nevada
Status: ACTIVE
Contact: Site Public Contact
Email: research@sncrf.org

Urology Specialists of Nevada - Central
Status: ACTIVE
Contact: Site Public Contact
Email: research@sncrf.org

Urology Specialists of Nevada - Northwest
Status: ACTIVE
Contact: Site Public Contact
Email: research@sncrf.org

Urology Specialists of Nevada - Southwest
Status: ACTIVE
Contact: Site Public Contact
Email: research@sncrf.org

Pahrump
Hope Cancer Care of Nevada-Pahrump
Status: ACTIVE
Contact: Site Public Contact
Email: research@sncrf.org

Reno
Radiation Oncology Associates
Status: ACTIVE
Contact: Site Public Contact
Email: research@sncrf.org

Renown Regional Medical Center
Status: ACTIVE
Contact: Site Public Contact
Email: research@sncrf.org

Saint Mary's Regional Medical Center
Status: ACTIVE
Contact: Site Public Contact
Email: research@sncrf.org

NY
Auburn
Hematology Oncology Associates of Central New York-Auburn
Status: ACTIVE
Contact: Site Public Contact

Bronx
James J Peters VA Medical Center
Status: ACTIVE
Contact: Site Public Contact
Email: kl2965@cumc.columbia.edu

Canandiaqua
Sands Cancer Center
Status: ACTIVE
Contact: Site Public Contact

East Syracuse
Hematology Oncology Associates of Central New York-East Syracuse
Status: ACTIVE
Contact: Site Public Contact

Elmira
Arnot Ogden Medical Center / Falck Cancer Center
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact

Glens Falls
Glens Falls Hospital
Status: ACTIVE
Contact: Site Public Contact

Middletown
Garnet Health Medical Center
Status: ACTIVE
Contact: Site Public Contact
Email: jgerlach@garnethealth.org

Oneida
Upstate Cancer Center Radiation Oncology at Oneida
Status: ACTIVE
Contact: Site Public Contact
Email: BinghamE@upstate.edu

Upstate Cancer Center at Oneida
Status: ACTIVE
Contact: Site Public Contact
Email: McDowelE@upstate.edu

Oswego
Upstate Cancer Center Radiation Oncology at Oswego
Status: ACTIVE
Contact: Site Public Contact
Email: BinghamE@upstate.edu

Upstate Cancer Center at Oswego
Status: ACTIVE
Contact: Site Public Contact
Email: McDowelE@upstate.edu

Rochester
Highland Hospital
Status: ACTIVE
Contact: Site Public Contact

University of Rochester
Status: ACTIVE
Contact: Site Public Contact

Stony Brook
Stony Brook University Medical Center
Status: ACTIVE
Contact: Site Public Contact

Syracuse
Hematology Oncology Associates of Central New York-Onondaga Hill
Status: ACTIVE
Contact: Site Public Contact

State University of New York Upstate Medical University
Status: ACTIVE
Contact: Site Public Contact

Upstate Cancer Center at Hill Radiation Oncology
Status: ACTIVE
Contact: Site Public Contact
Email: BinghamE@upstate.edu

OH
Akron
Summa Health System - Akron Campus
Status: ACTIVE
Contact: Site Public Contact
Email: cancerresearch@summahealth.org

Barberton
Summa Health System - Barberton Campus
Status: ACTIVE
Contact: Site Public Contact
Email: cancerresearch@summahealth.org

Beavercreek
Indu and Raj Soin Medical Center
Status: ACTIVE
Contact: Site Public Contact
Email: clinical.trials@daytonncorp.org

Belpre
Strecker Cancer Center-Belpre
Status: ACTIVE
Contact: Site Public Contact
Email: sheree@columbusccop.org

Boardman
Saint Elizabeth Boardman Hospital
Status: ACTIVE
Contact: Site Public Contact
Email: clinical.trials@daytonncorp.org

Canton
Cleveland Clinic Mercy Hospital
Status: ACTIVE
Contact: Site Public Contact

Mercy Hematology and Oncology Associates Inc
Status: TEMPORARILY_CLOSED_TO_ACCRUAL
Contact: Site Public Contact

Centerville
Dayton Physicians LLC-Miami Valley South
Status: ACTIVE
Contact: Site Public Contact
Email: clinical.trials@daytonncorp.org

Miami Valley Hospital South
Status: TEMPORARILY_CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: clinical.trials@daytonncorp.org

Chillicothe
Adena Regional Medical Center
Status: ACTIVE
Contact: Site Public Contact
Email: sheree@columbusccop.org

Cincinnati
Bethesda North Hospital
Status: ACTIVE
Contact: Site Public Contact
Email: ResearchInstituteInquiries@CommonSpirit.org

Good Samaritan Hospital - Cincinnati
Status: ACTIVE
Contact: Site Public Contact
Email: ResearchInstituteInquiries@CommonSpirit.org

Oncology Hematology Care Inc-Kenwood
Status: ACTIVE
Contact: Site Public Contact
Email: clinical.trials@daytonncorp.org

TriHealth Cancer Institute-Anderson
Status: ACTIVE
Contact: Site Public Contact
Email: ResearchInstituteInquiries@CommonSpirit.org

TriHealth Cancer Institute-Westside
Status: ACTIVE
Contact: Site Public Contact
Email: ResearchInstituteInquiries@CommonSpirit.org

Cleveland
Cleveland Clinic Cancer Center / Fairview Hospital
Status: ACTIVE
Contact: Site Public Contact
Email: TaussigResearch@ccf.org

Cleveland Clinic Foundation
Status: ACTIVE
Contact: Site Public Contact
Email: TaussigResearch@ccf.org

MetroHealth Medical Center
Status: ACTIVE
Contact: Site Public Contact
Email: dstrater@metrohealth.org

Columbus
Columbus Oncology and Hematology Associates Inc
Status: ACTIVE
Contact: Site Public Contact
Email: sheree@columbusccop.org

Doctors Hospital
Status: ACTIVE
Contact: Site Public Contact
Email: sheree@columbusccop.org

Grant Medical Center
Status: ACTIVE
Contact: Site Public Contact
Email: sheree@columbusccop.org

Mount Carmel East Hospital
Status: ACTIVE
Contact: Site Public Contact
Email: sheree@columbusccop.org

Mount Carmel Health Center West
Status: ACTIVE
Contact: Site Public Contact
Email: sheree@columbusccop.org

Riverside Methodist Hospital
Status: ACTIVE
Contact: Site Public Contact
Email: sheree@columbusccop.org

The Mark H Zangmeister Center
Status: ACTIVE
Contact: Site Public Contact
Email: sheree@columbusccop.org

Dayton
Dayton Physician LLC-Miami Valley Hospital North
Status: ACTIVE
Contact: Site Public Contact
Email: clinical.trials@daytonncorp.org

Miami Valley Hospital
Status: TEMPORARILY_CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: clinical.trials@daytonncorp.org

Miami Valley Hospital North
Status: TEMPORARILY_CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: clinical.trials@daytonncorp.org

Delaware
Delaware Health Center-Grady Cancer Center
Status: ACTIVE
Contact: Site Public Contact
Email: sheree@columbusccop.org

Grady Memorial Hospital
Status: ACTIVE
Contact: Site Public Contact
Email: sheree@columbusccop.org

Dublin
Columbus Oncology and Hematology Associates
Status: ACTIVE
Contact: Site Public Contact
Email: sheree@columbusccop.org

Dublin Methodist Hospital
Status: ACTIVE
Contact: Site Public Contact
Email: sheree@columbusccop.org

Findlay
Armes Family Cancer Center
Status: ACTIVE
Contact: Site Public Contact
Email: clinical.trials@daytonncorp.org

Blanchard Valley Hospital
Status: ACTIVE
Contact: Site Public Contact
Email: clinical.trials@daytonncorp.org

Orion Cancer Care
Status: ACTIVE
Contact: Site Public Contact
Email: clinical.trials@daytonncorp.org

Franklin
Atrium Medical Center-Middletown Regional Hospital
Status: TEMPORARILY_CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: clinical.trials@daytonncorp.org

Dayton Physicians LLC-Atrium
Status: ACTIVE
Contact: Site Public Contact
Email: clinical.trials@daytonncorp.org

Gahanna
Central Ohio Breast and Endocrine Surgery
Status: ACTIVE
Contact: Site Public Contact
Email: sheree@columbusccop.org

Greenville
Dayton Physicians LLC-Wayne
Status: ACTIVE
Contact: Site Public Contact
Email: clinical.trials@daytonncorp.org

Wayne Hospital
Status: ACTIVE
Contact: Site Public Contact
Email: clinical.trials@daytonncorp.org

Grove City
Mount Carmel Grove City Hospital
Status: ACTIVE
Contact: Site Public Contact
Email: sheree@columbusccop.org

Independence
Cleveland Clinic Cancer Center Independence
Status: ACTIVE
Contact: Site Public Contact
Email: TaussigResearch@ccf.org

Kettering
First Dayton Cancer Care
Status: TEMPORARILY_CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: clinical.trials@daytonncorp.org

Greater Dayton Cancer Center
Status: ACTIVE
Contact: Site Public Contact
Email: clinical.trials@daytonncorp.org

Kettering Medical Center
Status: ACTIVE
Contact: Site Public Contact
Email: clinical.trials@daytonncorp.org

Lancaster
Fairfield Medical Center
Status: ACTIVE
Contact: Site Public Contact
Email: sheree@columbusccop.org

Lima
Saint Rita's Medical Center
Status: TEMPORARILY_CLOSED_TO_ACCRUAL
Contact: Site Public Contact

Mansfield
Cleveland Clinic Cancer Center Mansfield
Status: ACTIVE
Contact: Site Public Contact
Email: TaussigResearch@ccf.org

OhioHealth Mansfield Hospital
Status: ACTIVE
Contact: Site Public Contact
Email: sheree@columbusccop.org

Marietta
Marietta Memorial Hospital
Status: ACTIVE
Contact: Site Public Contact
Email: sheree@columbusccop.org

Marion
OhioHealth Marion General Hospital
Status: ACTIVE
Contact: Site Public Contact
Email: sheree@columbusccop.org

Mayfield Heights
Hillcrest Hospital Cancer Center
Status: ACTIVE
Contact: Site Public Contact
Email: TaussigResearch@ccf.org

Medina
Summa Health Medina Medical Center
Status: ACTIVE
Contact: Site Public Contact
Email: cancerresearch@summahealth.org

Mount Vernon
Knox Community Hospital
Status: ACTIVE
Contact: Site Public Contact
Email: sheree@columbusccop.org

Newark
Licking Memorial Hospital
Status: ACTIVE
Contact: Site Public Contact
Email: sheree@columbusccop.org

Newark Radiation Oncology
Status: ACTIVE
Contact: Site Public Contact
Email: sheree@columbusccop.org

Perrysburg
Mercy Health Perrysburg Cancer Center
Status: ACTIVE
Contact: Site Public Contact
Email: sheree@columbusccop.org

Portsmouth
Southern Ohio Medical Center
Status: ACTIVE
Contact: Site Public Contact
Email: sheree@columbusccop.org

Sandusky
North Coast Cancer Care
Status: ACTIVE
Contact: Site Public Contact
Email: TaussigResearch@ccf.org

Springfield
Springfield Regional Cancer Center
Status: ACTIVE
Contact: Site Public Contact
Email: clinical.trials@daytonncorp.org

Springfield Regional Medical Center
Status: ACTIVE
Contact: Site Public Contact
Email: clinical.trials@daytonncorp.org

Strongsville
Cleveland Clinic Cancer Center Strongsville
Status: ACTIVE
Contact: Site Public Contact
Email: TaussigResearch@ccf.org

Toledo
Mercy Health - Saint Anne Hospital
Status: ACTIVE
Contact: Site Public Contact
Email: sheree@columbusccop.org

Saint Vincent Mercy Medical Center
Status: ACTIVE
Contact: Site Public Contact
Email: sheree@columbusccop.org

Troy
Dayton Physicians LLC-Upper Valley
Status: ACTIVE
Contact: Site Public Contact
Email: clinical.trials@daytonncorp.org

Upper Valley Medical Center
Status: TEMPORARILY_CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: clinical.trials@daytonncorp.org

Warren
Saint Joseph Warren Hospital
Status: ACTIVE
Contact: Site Public Contact
Email: clinical.trials@daytonncorp.org

Warrensville Heights
South Pointe Hospital
Status: ACTIVE
Contact: Site Public Contact
Email: TaussigResearch@ccf.org

Westerville
Saint Ann's Hospital
Status: ACTIVE
Contact: Site Public Contact
Email: sheree@columbusccop.org

Wooster
Cleveland Clinic Wooster Family Health and Surgery Center
Status: ACTIVE
Contact: Site Public Contact
Email: TaussigResearch@ccf.org

Youngstown
Saint Elizabeth Youngstown Hospital
Status: ACTIVE
Contact: Site Public Contact
Email: clinical.trials@daytonncorp.org

Zanesville
Genesis Healthcare System Cancer Care Center
Status: ACTIVE
Contact: Site Public Contact
Email: sheree@columbusccop.org

OK
Lawton
Cancer Centers of Southwest Oklahoma Research
Status: ACTIVE
Contact: Site Public Contact

Oklahoma City
Integris Cancer Institute of Oklahoma
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact

Integris Southwest Medical Center
Status: TEMPORARILY_CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: ctsucontact@westat.com

Mercy Hospital Oklahoma City
Status: ACTIVE
Contact: Site Public Contact

University of Oklahoma Health Sciences Center
Status: ACTIVE
Contact: Site Public Contact
Email: ou-clinical-trials@ouhsc.edu

OR
Baker City
Saint Alphonsus Medical Center-Baker City
Status: ACTIVE
Contact: Site Public Contact
Email: mccinfo@mtcancer.org

Bend
Saint Charles Health System
Status: ACTIVE
Contact: Site Public Contact
Email: nosall@stcharleshealthcare.org

Clackamas
Clackamas Radiation Oncology Center
Status: ACTIVE
Contact: Site Public Contact
Email: CanRsrchStudies@providence.org

Providence Cancer Institute Clackamas Clinic
Status: ACTIVE
Contact: Site Public Contact
Email: CanRsrchStudies@providence.org

Coos Bay
Bay Area Hospital
Status: ACTIVE
Contact: Site Public Contact
Email: cherie.cox@bayareahospital.org

Corvallis
Good Samaritan Hospital
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: stmock@samhealth.org

Newberg
Providence Newberg Medical Center
Status: ACTIVE
Contact: Site Public Contact
Email: CanRsrchStudies@providence.org

Ontario
Saint Alphonsus Medical Center-Ontario
Status: ACTIVE
Contact: Site Public Contact
Email: mccinfo@mtcancer.org

Portland
Providence Portland Medical Center
Status: ACTIVE
Contact: Site Public Contact
Email: CanRsrchStudies@providence.org

Providence Saint Vincent Medical Center
Status: ACTIVE
Contact: Site Public Contact
Email: CanRsrchStudies@providence.org

Redmond
Saint Charles Health System-Redmond
Status: ACTIVE
Contact: Site Public Contact

PA
Allentown
Lehigh Valley Hospital-Cedar Crest
Status: ACTIVE
Contact: Site Public Contact
Email: Morgan_M.Horton@lvhn.org

Altoona
UPMC Altoona
Status: ACTIVE
Contact: Site Public Contact
Email: ecog.rss@jimmy.harvard.edu

Beaver
UPMC-Heritage Valley Health System Beaver
Status: ACTIVE
Contact: Site Public Contact
Email: haneydl@upmc.edu

Bethlehem
Lehigh Valley Hospital - Muhlenberg
Status: ACTIVE
Contact: Site Public Contact
Email: Morgan_M.Horton@lvhn.org

Bryn Mawr
Bryn Mawr Hospital
Status: ACTIVE
Contact: Site Public Contact
Email: turzoe@mlhs.org

Carlisle
Carlisle Regional Cancer Center
Status: ACTIVE
Contact: Site Public Contact
Email: ecog.rss@jimmy.harvard.edu

Chadds Ford
Christiana Care Health System-Concord Health Center
Status: ACTIVE
Contact: Site Public Contact
Email: mhayden@christianacare.org

Collegeville
Main Line Health Center-Collegeville
Status: ACTIVE
Contact: Site Public Contact
Email: turzoe@mlhs.org

Danville
Geisinger Medical Center
Status: ACTIVE
Contact: Site Public Contact
Email: HemonCCTrials@geisinger.edu

East Stroudsburg
Pocono Medical Center
Status: ACTIVE
Contact: Site Public Contact
Email: Morgan_M.Horton@lvhn.org

Erie
UPMC Hillman Cancer Center Erie
Status: ACTIVE
Contact: Site Public Contact
Email: haneydl@upmc.edu

Exton
Main Line Health Center-Exton
Status: ACTIVE
Contact: Site Public Contact
Email: turzoe@mlhs.org

Farrell
UPMC Cancer Center at UPMC Horizon
Status: ACTIVE
Contact: Site Public Contact
Email: ecog.rss@jimmy.harvard.edu

Greensburg
UPMC Cancer Centers - Arnold Palmer Pavilion
Status: ACTIVE
Contact: Site Public Contact

Harrisburg
UPMC Pinnacle Cancer Center / Community Osteopathic Campus
Status: ACTIVE
Contact: Site Public Contact
Email: klitchfield@PINNACLEHEALTH.org

UPMC Pinnacle Harrisburg
Status: ACTIVE
Contact: Site Public Contact
Email: ecog.rss@jimmy.harvard.edu

Hazleton
Geisinger Medical Center-Cancer Center Hazleton
Status: ACTIVE
Contact: Site Public Contact
Email: HemonCCTrials@geisinger.edu

Lehigh Valley Hospital-Hazleton
Status: ACTIVE
Contact: Site Public Contact
Email: Morgan_M.Horton@lvhn.org

Hershey
Penn State Milton S Hershey Medical Center
Status: ACTIVE
Contact: Site Public Contact
Email: CTO@hmc.psu.edu

Johnstown
UPMC-Johnstown / John P. Murtha Regional Cancer Center
Status: ACTIVE
Contact: Site Public Contact

Lewisburg
Geisinger Medical Oncology-Lewisburg
Status: ACTIVE
Contact: Site Public Contact
Email: HemonCCTrials@geisinger.edu

McKeesport
UPMC Cancer Center at UPMC McKeesport
Status: ACTIVE
Contact: Site Public Contact

Mechanicsburg
UPMC Hillman Cancer Center at Rocco And Nancy Ortenzio Cancer Pavilion
Status: ACTIVE
Contact: Site Public Contact
Email: haneydl@upmc.edu

Media
Riddle Memorial Hospital
Status: ACTIVE
Contact: Site Public Contact
Email: turzoe@mlhs.org

Monroeville
UPMC Cancer Center - Monroeville
Status: ACTIVE
Contact: Site Public Contact
Email: ecog.rss@jimmy.harvard.edu

Moon Township
UPMC-Coraopolis / Heritage Valley Radiation Oncology
Status: ACTIVE
Contact: Site Public Contact

Paoli
Paoli Memorial Hospital
Status: ACTIVE
Contact: Site Public Contact
Email: turzoe@mlhs.org

Pittsburgh
UPMC-Magee Womens Hospital
Status: ACTIVE
Contact: Site Public Contact

UPMC-Passavant Hospital
Status: ACTIVE
Contact: Site Public Contact

UPMC-Saint Clair Hospital Cancer Center
Status: ACTIVE
Contact: Site Public Contact

UPMC-Saint Margaret
Status: ACTIVE
Contact: Site Public Contact

UPMC-Shadyside Hospital
Status: ACTIVE
Contact: Site Public Contact

University of Pittsburgh Cancer Institute (UPCI)
Status: ACTIVE
Contact: Site Public Contact

Pottstown
Pottstown Hospital
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact

Pottsville
Geisinger Cancer Services-Pottsville
Status: ACTIVE
Contact: Site Public Contact
Email: HemonCCTrials@geisinger.edu

Sayre
Guthrie Medical Group PC-Robert Packer Hospital
Status: ACTIVE
Contact: Site Public Contact

Scranton
Community Medical Center
Status: ACTIVE
Contact: Site Public Contact
Email: HemonCCTrials@geisinger.edu

Seneca
UPMC Cancer Center at UPMC Northwest
Status: ACTIVE
Contact: Site Public Contact

Uniontown
UPMC Uniontown Hospital Radiation Oncology
Status: ACTIVE
Contact: Site Public Contact

Washington
UPMC Washington Hospital Radiation Oncology
Status: ACTIVE
Contact: Site Public Contact
Email: cancer@washingtonhospital.org

Wilkes-Barre
Geisinger Wyoming Valley / Henry Cancer Center
Status: ACTIVE
Contact: Site Public Contact
Email: HemonCCTrials@geisinger.edu

Wynnewood
Lankenau Medical Center
Status: ACTIVE
Contact: Site Public Contact
Email: turzoe@mlhs.org

York
UPMC Memorial
Status: ACTIVE
Contact: Site Public Contact

SC
Gaffney
Gibbs Cancer Center-Gaffney
Status: ACTIVE
Contact: Site Public Contact
Email: kmertz-rivera@gibbscc.org

Greer
Gibbs Cancer Center-Pelham
Status: ACTIVE
Contact: Site Public Contact
Email: kmertz-rivera@gibbscc.org

Hilton Head Island
South Carolina Cancer Specialists PC
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: underberga@sjchs.org

The Radiation Oncology Center-Hilton Head / Bluffton
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: underberga@sjchs.org

Myrtle Beach
Carolina Regional Cancer Center
Status: ACTIVE
Contact: Site Public Contact

Spartanburg
North Grove Medical Park
Status: ACTIVE
Contact: Site Public Contact

Spartanburg Medical Center
Status: ACTIVE
Contact: Site Public Contact
Email: kmertz-rivera@gibbscc.org

Spartanburg Medical Center - Mary Black Campus
Status: ACTIVE
Contact: Site Public Contact

Union
MGC Hematology Oncology-Union
Status: ACTIVE
Contact: Site Public Contact
Email: kmertz-rivera@gibbscc.org

TN
Collierville
Baptist Memorial Hospital and Cancer Center-Collierville
Status: ACTIVE
Contact: Site Public Contact
Email: BCCclintrials@bmhcc.org

Memphis
Baptist Memorial Hospital and Cancer Center-Memphis
Status: ACTIVE
Contact: Site Public Contact
Email: BCCclintrials@bmhcc.org

TX
Bryan
Saint Joseph Regional Cancer Center
Status: TEMPORARILY_CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: ResearchInstituteInquiries@CommonSpirit.org

VA
Charlottesville
University of Virginia Cancer Center
Status: ACTIVE
Contact: Site Public Contact
Email: uvacancertrials@hscmail.mcc.virginia.edu

Lynchburg
Centra Lynchburg Hematology-Oncology Clinic Inc
Status: ACTIVE
Contact: Site Public Contact
Email: Kevin.Patel@centrahealth.com

Martinsville
Sovah Health Martinsville
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: sharon.hubbard@lpnt.net

Mechanicsville
VCU Massey Cancer Center at Hanover Medical Park
Status: ACTIVE
Contact: Site Public Contact
Email: CTOclinops@vcu.edu

Richmond
VCU Massey Cancer Center at Stony Point
Status: ACTIVE
Contact: Site Public Contact
Email: ctoclinops@vcu.edu

Virginia Cancer Institute
Status: ACTIVE
Contact: Site Public Contact
Email: smoore@vacancer.com

Virginia Commonwealth University / Massey Cancer Center
Status: ACTIVE
Contact: Site Public Contact
Email: CTOclinops@vcu.edu

South Hill
VCU Community Memorial Health Center
Status: ACTIVE
Contact: Site Public Contact
Email: sherman.baker@vcuhealth.org

Winchester
Shenandoah Oncology PC
Status: CLOSED_TO_ACCRUAL
Contact: Site Public Contact
Email: William.Houck@usoncology.com

VT
Berlin
Central Vermont Medical Center / National Life Cancer Treatment
Status: ACTIVE
Contact: Site Public Contact

Burlington
University of Vermont Medical Center
Status: ACTIVE
Contact: Site Public Contact
Email: rpo@uvm.edu

University of Vermont and State Agricultural College
Status: ACTIVE
Contact: Site Public Contact
Email: rpo@uvm.edu

Saint Johnsbury
Norris Cotton Cancer Center-North
Status: ACTIVE
Contact: Site Public Contact

WI
Antigo
Langlade Hospital and Cancer Center
Status: ACTIVE
Contact: Site Public Contact
Email: Juli.Alford@aspirus.org

Appleton
ThedaCare Regional Cancer Center
Status: ACTIVE
Contact: Site Public Contact
Email: ResearchDept@thedacare.org

Ashland
Duluth Clinic Ashland
Status: ACTIVE
Contact: Site Public Contact
Email: CancerTrials@EssentiaHealth.org

Northwest Wisconsin Cancer Center
Status: ACTIVE
Contact: Site Public Contact
Email: CancerTrials@EssentiaHealth.org

Burlington
Aurora Cancer Care-Southern Lakes VLCC
Status: ACTIVE
Contact: Site Public Contact
Email: ncorp@aurora.org

Eau Claire
HSHS Sacred Heart Hospital
Status: ACTIVE
Contact: Site Public Contact
Email: ewd_research_admin@hshs.org

Marshfield Medical Center-EC Cancer Center
Status: ACTIVE
Contact: Site Public Contact
Email: oncology.clinical.trials@marshfieldresearch.org

Germantown
Aurora Health Care Germantown Health Center
Status: ACTIVE
Contact: Site Public Contact
Email: ncorp@aurora.org

Grafton
Aurora Cancer Care-Grafton
Status: ACTIVE
Contact: Site Public Contact
Email: ncorp@aurora.org

Green Bay
Aurora BayCare Medical Center
Status: ACTIVE
Contact: Site Public Contact
Email: ncorp@aurora.org

Saint Vincent Hospital Cancer Center Green Bay
Status: ACTIVE
Contact: Site Public Contact
Email: ewd_research_admin@hshs.org

Saint Vincent Hospital Cancer Center at Saint Mary's
Status: ACTIVE
Contact: Site Public Contact
Email: ewd_research_admin@hshs.org

Hayward
Essentia Health-Hayward Clinic
Status: ACTIVE
Contact: Site Public Contact
Email: CancerTrials@EssentiaHealth.org

Kenosha
Aurora Cancer Care-Kenosha South
Status: ACTIVE
Contact: Site Public Contact
Email: ncorp@aurora.org

La Crosse
Gundersen Lutheran Medical Center
Status: ACTIVE
Contact: Site Public Contact
Email: cancerctr@gundersenhealth.org

Madison
University of Wisconsin Carbone Cancer Center
Status: ACTIVE
Contact: Site Public Contact

Marinette
Aurora Bay Area Medical Group-Marinette
Status: ACTIVE
Contact: Site Public Contact
Email: ncorp@aurora.org

Marshfield
Marshfield Medical Center-Marshfield
Status: ACTIVE
Contact: Site Public Contact
Email: oncology.clinical.trials@marshfieldresearch.org

Medford
Aspirus Medford Hospital
Status: ACTIVE
Contact: Site Public Contact
Email: Beth.Knetter@aspirus.org

Menomonee Falls
Froedtert Menomonee Falls Hospital
Status: ACTIVE
Contact: Site Public Contact

Milwaukee
Aurora Cancer Care-Milwaukee
Status: ACTIVE
Contact: Site Public Contact
Email: ncorp@aurora.org

Aurora Saint Luke's Medical Center
Status: ACTIVE
Contact: Site Public Contact
Email: ncorp@aurora.org

Aurora Sinai Medical Center
Status: ACTIVE
Contact: Site Public Contact
Email: ncorp@aurora.org

Medical College of Wisconsin
Status: ACTIVE
Contact: Site Public Contact

Minocqua
Marshfield Clinic-Minocqua Center
Status: ACTIVE
Contact: Site Public Contact
Email: oncology.clinical.trials@marshfieldresearch.org

Mukwonago
ProHealth D N Greenwald Center
Status: ACTIVE
Contact: Site Public Contact
Email: research.institute@phci.org

New Richmond
Cancer Center of Western Wisconsin
Status: ACTIVE
Contact: Site Public Contact
Email: mmcorc@healthpartners.com

Oak Creek
Drexel Town Square Health Center
Status: ACTIVE
Contact: Site Public Contact

Oconomowoc
ProHealth Oconomowoc Memorial Hospital
Status: ACTIVE
Contact: Site Public Contact

Oshkosh
Vince Lombardi Cancer Clinic - Oshkosh
Status: ACTIVE
Contact: Site Public Contact
Email: ncorp@aurora.org

Racine
Aurora Cancer Care-Racine
Status: ACTIVE
Contact: Site Public Contact
Email: ncorp@aurora.org

Rice Lake
Marshfield Medical Center-Rice Lake
Status: ACTIVE
Contact: Site Public Contact
Email: oncology.clinical.trials@marshfieldresearch.org

Sheboygan
Vince Lombardi Cancer Clinic-Sheboygan
Status: ACTIVE
Contact: Site Public Contact
Email: ncorp@aurora.org

Spooner
Essentia Health-Spooner Clinic
Status: ACTIVE
Contact: Site Public Contact
Email: CancerTrials@EssentiaHealth.org

Stevens Point
Marshfield Medical Center-River Region at Stevens Point
Status: ACTIVE
Contact: Site Public Contact
Email: oncology.clinical.trials@marshfieldresearch.org

Sturgeon Bay
Saint Vincent Hospital Cancer Center at Sturgeon Bay
Status: ACTIVE
Contact: Site Public Contact
Email: ewd_research_admin@hshs.org

Summit
Aurora Medical Center in Summit
Status: ACTIVE
Contact: Site Public Contact
Email: ncorp@aurora.org

Superior
Essentia Health Saint Mary's Hospital - Superior
Status: ACTIVE
Contact: Site Public Contact

Two Rivers
Vince Lombardi Cancer Clinic-Two Rivers
Status: ACTIVE
Contact: Site Public Contact
Email: ncorp@aurora.org

Waukesha
ProHealth Waukesha Memorial Hospital
Status: ACTIVE
Contact: Site Public Contact

UW Cancer Center at ProHealth Care
Status: ACTIVE
Contact: Site Public Contact
Email: Chanda.miller@phci.org

Wausau
Aspirus Regional Cancer Center
Status: ACTIVE
Contact: Site Public Contact

Wauwatosa
Aurora Cancer Care-Milwaukee West
Status: ACTIVE
Contact: Site Public Contact
Email: ncorp@aurora.org

West Allis
Aurora West Allis Medical Center
Status: ACTIVE
Contact: Site Public Contact
Email: ncorp@aurora.org

West Bend
Froedtert West Bend Hospital / Kraemer Cancer Center
Status: ACTIVE
Contact: Site Public Contact

Weston
Marshfield Medical Center - Weston
Status: ACTIVE
Contact: Site Public Contact
Email: oncology.clinical.trials@marshfieldresearch.org

Wisconsin Rapids
Aspirus Cancer Care - Wisconsin Rapids
Status: ACTIVE
Contact: Site Public Contact

WV
Charleston
West Virginia University Charleston Division
Status: ACTIVE
Contact: Site Public Contact

Huntington
Edwards Comprehensive Cancer Center
Status: ACTIVE
Contact: Site Public Contact
Email: Christina.Cole@chhi.org

WY
Cheyenne
Cheyenne Regional Medical Center-West
Status: ACTIVE
Contact: Site Public Contact
Email: ccrp@co-cancerresearch.org

Cody
Billings Clinic-Cody
Status: ACTIVE
Contact: Site Public Contact
Email: research@billingsclinic.org

Sheridan
Welch Cancer Center
Status: ACTIVE
Contact: Site Public Contact
Email: mccinfo@mtcancer.org

PRIMARY OBJECTIVE:
I. To evaluate whether there is an improvement in overall survival with concomitant chemotherapy/radiation therapy/MEDI4736 (durvalumab) followed by one year (12 cycles) of MEDI4736 (durvalumab) as compared to concomitant chemotherapy/radiation followed by one year (12 cycles) of MEDI4736 (durvalumab).

SECONDARY OBJECTIVES:
I. To evaluate the difference in response using Response Evaluation Criteria in Solid Tumors (RECIST) 1.1 criteria to assess whether or not MEDI4736 (durvalumab) added to concomitant chemo/radiation results in an improvement in response rates.
II. To evaluate any difference in progression free survival (PFS) with concomitant chemotherapy/radiation therapy/MEDI4736 (durvalumab) followed by one year (12 cycles) of MEDI4736 (durvalumab) as compared to concomitant chemotherapy/radiotherapy followed by one year of MEDI4736 (durvalumab).
III. To evaluate whether the incidence of recurrence and recurrence pattern is affected by giving MEDI4736 (durvalumab) during chemo/radiation.
IV. To evaluate any difference in toxicity when MEDI4736 (durvalumab) is added to concomitant chemo/radiation using the Common Terminology Criteria for Adverse Events (CTCAE).

OUTLINE: 
STEP 1 (CONCURRENT THERAPY): Patients are randomized to 1 of 2 arms.

ARM A: Patients receive durvalumab intravenously (IV) over 60 minutes on days 1 and 15 of cycle 1 and day 1 of cycle 2. Patients also receive 1 of 3 treatment regimens per investigator choice: 1) etoposide IV over 60 minutes on days 1-5 and cisplatin IV over 60 minutes on days 1 and 8 every 28 days for 2 cycles; 2) pemetrexed disodium IV over 60 minutes and cisplatin IV over 60-120 minutes on day 1 every 21 days for 2 cycles; or 3) paclitaxel IV over 60 minutes and carboplatin IV over 30 minutes on day 1 every 7 days for 6 cycles. Treatment continues in the absence of disease progression or unacceptable toxicity. Beginning on day 1 of chemotherapy, patients receive radiation therapy 5 days a week for 6 weeks.

ARM B: Patients receive 1 of 3 investigator's choice treatment regimens and radiation therapy as in Arm A.

STEP 2 (CONSOLIDATION THERAPY): Within 14 days after the last dose of radiation (from Step 1), all patients then receive durvalumab IV over 60 minutes on day 1. Treatment repeats every 28 days for 12 cycles in the absence of disease progression or unacceptable toxicity.

After completion of study treatment, patients are followed up every 3 months if less than 2 years from study entry, every 6 months if 2-5 years from study entry, and then yearly for years 5-10 from study entry.

Interactive content above is from the official study record on the National Cancer Institute website, cancer.gov.


The ECOG-ACRIN Cancer Research Group designed this trial and is conducting it with funding from the National Cancer Institute through its National Clinical Trials Network.


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