Breast Cancer

EA1131



Testing Platinum-based Chemotherapy after Surgery in Triple-Negative Breast Cancers

STATUS: Closed to Accrual


This phase III trial compares the effect of cisplatin or carboplatin (platinum-based chemotherapy) to capecitabine after initial chemotherapy (neoadjuvant therapy) followed by surgery for the treatment of residual triple-negative breast cancer. Chemotherapy drugs, such as cisplatin, carboplatin, and capecitabine, work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. At present, upon completion of chemotherapy and surgery, the standard of care for patients with triple-negative breast cancer is observation. However, recent studies have shown that giving capecitabine after completion of chemotherapy and surgery is a better treatment than receiving no treatment and also that platinum-based chemotherapy after neoadjuvant therapy and surgery may prevent residual triple-negative breast cancer from returning. This trial compares the benefit of adding a platinum agent vs. capecitabine to the treatment regimen, following completion of neoadjuvant therapy and surgery in patients with residual triple-negative breast cancer.
  • ELIGIBILITY CRITERIA FOR SCREENING AND MOLECULAR PROFILING (STEP 0)

  • Eastern Cooperative Oncology Group (ECOG) performance status 0 or 1 within 2 weeks prior to screening

  • Female and male patients must have histologically confirmed invasive breast cancer that meets the following criteria: * Clinical stage II-III (American Joint Committee on Cancer [AJCC] 8th edition) at diagnosis, based on initial evaluation by clinical examination and/or breast imaging; no metastatic disease allowed * ER- and PR- should meet one of the following criteria: ** 1 to =< 10% cells stain positive, with weak intensity score ** =< 1% cells stain positive * HER2 negative (not eligible for anti-HER2 therapy) will be defined as: ** Immunohistochemistry (IHC) 0, 1+ without in situ hybridization (ISH) HER2/neu chromosome 17 ratio OR ** IHC 2+ and ISH HER2/neu chromosome 17 ratio non-amplified with ratio less than 2.0 and if reported average HER2 copy number < 6 signals/cells OR ** ISH HER2/neu chromosome 17 ratio non-amplified with ratio less than 2.0 and if reported average HER2 copy number < 6 signals/cells without IHC ** NOTE: patients that originally present with synchronous bilateral tumors are eligible provided both tumors are TNBC, and at least one of them fulfills the remainder eligibility criteria of the protocol; multifocal or multicentric breast cancers are eligible as long as all tumors fulfill eligibility criteria (please note that tumors that were not tested already do not need to be tested for protocol eligibility) ** NOTE: patients that have a discrepancy in ER/PR/HER2 status between original diagnosis and surgical specimen (only applicable if ER/PR/HER2 status were repeated; repeating it is not mandatory) are not eligible for study participation as long as the surgical specimen's ER/PR/HER2 status fulfills eligibility criteria ** NOTE: Special histologies (i.e. metaplastic, adenoid cystic, apocrine, etc.) are eligible as long as ER/PR/HER2 testing fulfills eligibility criteria ** NOTE: Patients with inflammatory TNBC at presentation are eligible

  • Patients must have received neoadjuvant taxane +/- anthracycline; patients must NOT have received cisplatin or carboplatin or capecitabine as part of their neoadjuvant therapy regimen * NOTE: Patients who received preoperative therapy as part of a clinical trial may enroll * NOTE: Patients that were not able to complete their planned neoadjuvant chemotherapy for any reason (i.e. toxicities, etc.) are eligible to participate as long as no further systemic standard of care therapy is planned by the treating physician * NOTE: Patients must have received a taxane for at least 1 cycle as part of their neoadjuvant therapy regimen

  • Must have completed definitive resection of primary tumor * Negative margins for both invasive and ductal carcinoma in situ (DCIS) are desirable, however patients with positive margins may enroll if the treatment team believes no further surgery is possible and patient has received radiotherapy; patients with margins positive for lobular carcinoma in situ (LCIS) are eligible * Either mastectomy or breast conserving surgery (including lumpectomy or partial mastectomy) is acceptable * Sentinel node biopsy either pre or post neoadjuvant chemotherapy (i.e. at the time of definitive surgery) are allowed; axillary dissection is encouraged in patients with lymph node involvement, but is not mandatory

  • Post neoadjuvant chemotherapy, patients must be found to have residual invasive cancer in the breast at the time of definitive surgery; residual cancer is defined as a contiguous focus of residual invasive cancer, in the breast, measuring >= 1 cm in diameter, and with more than minimal cellularity, as per local pathologist determination; please note that in patients that have multifocal or multicentric residual tumors these lesions cannot be added up; the biggest lesion has to measure >= 1 cm in diameter; this is required due to constraints in deoxyribonucleic acid (DNA) extraction for PAM50 analysis * NOTE: The presence of ductal carcinoma in situ (DCIS) without invasion does not qualify as residual invasive disease in the breast * NOTE: Despite lymph node involvement if residual invasive cancer in the breast is < 1 cm in diameter patients are not eligible for participation

  • Radiotherapy may be given before or after protocol treatment per standard of care guidelines; when radiotherapy is planned prior to protocol treatment administration, patients may be registered and screened while receiving radiation, and it has to be complete prior to randomization * Post-mastectomy radiotherapy is required for all patients with the following: ** Primary tumor >= 5 cm or involvement of lymph nodes (prior to neoadjuvant chemotherapy [clinically] or at the time of definitive surgery) or involvement of lymph nodes at the time of definitive surgery ** For patients with primary tumors < 5 cm or without lymph node involvement prior to neoadjuvant chemotherapy and at the time of definitive surgery, provision of post-mastectomy radiotherapy is at the discretion of the treating physician ** Radiation of regional nodal basins is at the discretion of the treating radiation oncologist * NOTE: Breast radiotherapy (whole breast or partial) is required for patients who underwent breast-conserving therapy, including lumpectomy or partial mastectomy

  • Hemoglobin (Hgb) > 9.0 g/dL (must be obtained within 8 weeks prior to screening for protocol therapy)

  • Platelets > 100,000 mm^3 (must be obtained within 8 weeks prior to screening for protocol therapy)

  • Absolute neutrophil count (ANC) > 1500 mm^3 (must be obtained within 8 weeks prior to screening for protocol therapy)

  • Calculated creatinine clearance of > 50 mL/min using the Cockcroft-Gault formula (must be obtained within 8 weeks prior to screening for protocol therapy)

  • Bilirubin =< 1.5 x ULN upper limit of normal (except in patients with documented Gilbertโ€™s disease, who must have a total bilirubin =< 3.0 mg/dL) (must be obtained within 8 weeks prior to screening for protocol therapy)

  • Aspartate aminotransferase (AST, serum glutamic oxaloacetic transaminase [SGOT]) =< 2.5 x upper limit of normal (ULN) (must be obtained within 8 weeks prior to screening for protocol therapy)

  • Alanine aminotransferase (ALT, serum glutamate pyruvate transaminase [SGPT]) =< 2.5 x ULN (must be obtained within 8 weeks prior to screening for protocol therapy)

  • Adjuvant chemotherapy after surgery other than that specified in this protocol is not allowed; luteinizing hormone-releasing hormone (LHRH) agonists and adjuvant bisphosphonate or denosumab use is allowed

  • Patients must have archived formalin-fixed paraffin-embedded (FFPE) tumor tissue specimen from the residual disease on the definitive surgical specimen available for PAM50 analysis * Tumor tissue specimen from the definitive surgery has been collected and is ready to ship to the ECOG-American College of Radiology Imaging Network (ACRIN) Central Biorepository and Pathology Facility (EA CBPF) within 21 weeks post-surgery; the EA CBPF will notify the ECOG-ACRIN Operations Office and submitting institution of receipt of the tumor tissue specimen * NOTE: Tissue must and can be submitted any time during screening period, even if patient is getting radiation * NOTE: Every effort should be made to submit the tumor tissue specimen to the EA CBPF immediately

  • No history of TNBC invasive breast cancer within 5 years of enrollment, no concurrent malignancies except for synchronous bilateral tumors that are TNBC, skin, thyroid, or hematologic cancers with low metastatic/death potential (i.e. squamous cell or basal cell skin cancers, DCIS, chronic lymphocytic leukemia [CLL], etc.). Patients are eligible if they had any other cancers that were treated prior to screening and are without evidence of recurrence

  • No clinically significant infections as judged by the treating investigator. Concurrent illnesses that are well controlled with medical management are allowed

  • Patients with active >= Common Terminology Criteria for Adverse Events (CTCAE) version (v.) 4 grade 2 neuropathy are ineligible

  • ELIGIBILITY CRITERIA FOR RANDOMIZATION (STEP 1): No specific timeframe between registration and randomization needs to be observed, as long as: * After assignment of randomization patients must begin cycle 1/ day 1 (platinum based or capecitabine chemotherapy) within 6 weeks (30 working days) of the randomization date * Randomization occurs no more than 24 weeks from surgery date (i.e. subsequent surgeries for re-excision of margins or lymph nodes or reconstruction do not apply)

  • ELIGIBILITY CRITERIA FOR RANDOMIZATION (STEP 1): Must have confirmation from EA CBPF of receipt of formalin-fixed paraffin-embedded tumor tissue specimen (FFPE) of the residual disease in the breast resected at the time of definitive surgery

  • ELIGIBILITY CRITERIA FOR RANDOMIZATION (STEP 1): ECOG performance status 0 or 1 within 2 weeks prior to randomization

  • ELIGIBILITY CRITERIA FOR RANDOMIZATION (STEP 1): Radiotherapy, if applicable, may be given before or after protocol treatment; when radiotherapy is planned prior to protocol treatment administration, patients must have completed adjuvant radiotherapy >= 2 weeks prior to randomization for protocol therapy, if applicable

  • ELIGIBILITY CRITERIA FOR RANDOMIZATION (STEP 1): Patients must have completed treatment with any investigational agent >= 30 days prior to randomization for protocol therapy initiation (cycle 1/day 1)

  • ELIGIBILITY CRITERIA FOR RANDOMIZATION (STEP 1): Patients must be randomized within 24 weeks from surgery date (i.e. subsequent surgeries for re-excision of margins or lymph nodes or reconstruction do not apply)

  • ELIGIBILITY CRITERIA FOR RANDOMIZATION (STEP 1): Women of childbearing potential and sexually active males must be strongly advised to use an accepted and effective method of contraception or to abstain from sexual intercourse for the duration of their participation in the study

  • ELIGIBILITY CRITERIA FOR RANDOMIZATION (STEP 1): Hemoglobin (Hgb) > 9.0 g/dL (must be obtained within 4 weeks prior to randomization)

  • ELIGIBILITY CRITERIA FOR RANDOMIZATION (STEP 1): Platelets > 100,000 mm^3 (must be obtained within 4 weeks prior to randomization)

  • ELIGIBILITY CRITERIA FOR RANDOMIZATION (STEP 1): Absolute neutrophil count (ANC) > 1500 mm^3 (must be obtained within 4 weeks prior to randomization)

  • ELIGIBILITY CRITERIA FOR RANDOMIZATION (STEP 1): International normalized ratio (INR) =< 3 (to be done/tested only for subjects on warfarin) (must be obtained within 4 weeks prior to randomization)

  • ELIGIBILITY CRITERIA FOR RANDOMIZATION (STEP 1): Calculated creatinine clearance of > 50 mL/min using the Cockcroft-Gault formula (must be obtained within 4 weeks prior to randomization)

  • ELIGIBILITY CRITERIA FOR RANDOMIZATION (STEP 1): Bilirubin =< 1.5 x ULN (except in patients with documented Gilbertโ€™s disease, who must have a total bilirubin =< 3.0 mg/dL) (must be obtained within 4 weeks prior to randomization)

  • ELIGIBILITY CRITERIA FOR RANDOMIZATION (STEP 1): Aspartate aminotransferase (AST, SGOT) =< 2.5 x ULN (must be obtained within 4 weeks prior to randomization)

  • ELIGIBILITY CRITERIA FOR RANDOMIZATION (STEP 1): Alanine aminotransferase (ALT, SGPT) =< 2.5 x ULN (must be obtained within 4 weeks prior to randomization)

  • ELIGIBILITY CRITERIA FOR RANDOMIZATION (STEP 1): Women must not be pregnant or breast-feeding due to risk of teratogenicity/ toxicity with capecitabine or platinum-based therapy; all females of childbearing potential must have a blood test or urine study within 2 weeks prior to randomization to rule out pregnancy * A female of childbearing potential is any woman that has achieved menarche at some point, regardless of sexual orientation or whether they have undergone tubal ligation, who meets the following criteria: 1) has not undergone a hysterectomy or bilateral oophorectomy; or 2) has not been naturally postmenopausal for at least 24 consecutive months (i.e., has had menses at any time in the preceding 24 consecutive months)

  • Live vaccines are not permitted during study treatment period (but are permitted after study treatment completion), but all others (inactivated, micro ribonucleic acid [mRNA]-based, adenovirus, etc.) including coronavirus disease 2019 (COVID) vaccine are permitted before, during and after study treatment

  • Use of (any) anti-coagulants are allowed during study

South Africa
Pretoria
University Of Pretoria
Contact: Site Public Contact

United States
AK
Anchorage
Alaska Breast Care and Surgery LLC
Contact: Site Public Contact
Email: AKPAMC.OncologyResearchSupport@providence.org

Alaska Oncology and Hematology LLC
Contact: Site Public Contact
Email: AKPAMC.OncologyResearchSupport@providence.org

Alaska Regional Hospital
Contact: Site Public Contact

Alaska Women's Cancer Care
Contact: Site Public Contact
Email: AKPAMC.OncologyResearchSupport@providence.org

Anchorage Associates in Radiation Medicine
Contact: Site Public Contact
Email: AKPAMC.OncologyResearchSupport@providence.org

Anchorage Oncology Centre
Contact: Site Public Contact
Email: AKPAMC.OncologyResearchSupport@providence.org

Anchorage Radiation Therapy Center
Contact: Site Public Contact
Email: AKPAMC.OncologyResearchSupport@providence.org

Katmai Oncology Group
Contact: Site Public Contact
Email: AKPAMC.OncologyResearchSupport@providence.org

Providence Alaska Medical Center
Contact: Site Public Contact
Email: AKPAMC.OncologyResearchSupport@providence.org

Fairbanks
Fairbanks Memorial Hospital
Contact: Site Public Contact
Email: Veronica.Stevenson@foundationhealth.org

AL
Mobile
Mobile Infirmary Medical Center
Contact: Site Public Contact

University of South Alabama Mitchell Cancer Institute
Contact: Site Public Contact
Email: pfrancisco@usouthal.edu

AR
Ft. Smith
Mercy Hospital Fort Smith
Contact: Site Public Contact

Hot Springs
CHI Saint Vincent Cancer Center Hot Springs
Contact: Site Public Contact
Email: clinicaltrials@sfmc-gi.org

AZ
Kingman
Kingman Regional Medical Center
Contact: Site Public Contact
Email: ecog.rss@jimmy.harvard.edu

Phoenix
Cancer Center at Saint Joseph's
Contact: Site Public Contact

Tucson
Banner University Medical Center - Tucson
Contact: Site Public Contact
Email: aselegue@email.arizona.edu

University of Arizona Cancer Center-North Campus
Contact: Site Public Contact

CA
Antioch
Kaiser Permanente-Deer Valley Medical Center
Contact: Site Public Contact
Email: Kpoct@kp.org

Arroyo Grande
Mission Hope Medical Oncology - Arroyo Grande
Contact: Site Public Contact
Email: research@dignityhealth.org

PCR Oncology
Contact: Site Public Contact
Email: research@sncrf.org

Auburn
Sutter Auburn Faith Hospital
Contact: Site Public Contact
Email: bernicl@sutterhealth.org

Sutter Cancer Centers Radiation Oncology Services-Auburn
Contact: Site Public Contact
Email: bernicl@sutterhealth.org

Berkeley
Alta Bates Summit Medical Center-Herrick Campus
Contact: Site Public Contact
Email: bernicl@sutterhealth.org

Burbank
Providence Saint Joseph Medical Center/Disney Family Cancer Center
Contact: Site Public Contact
Email: Najee.Boucher@providence.org

Burlingame
Mills-Peninsula Medical Center
Contact: Site Public Contact
Email: bernicl@sutterhealth.org

Cameron Park
Sutter Cancer Centers Radiation Oncology Services-Cameron Park
Contact: Site Public Contact
Email: bernicl@sutterhealth.org

Castro Valley
Eden Hospital Medical Center
Contact: Site Public Contact
Email: bernicl@sutterhealth.org

Davis
Sutter Davis Hospital
Contact: Site Public Contact
Email: bernicl@sutterhealth.org

Dublin
Epic Care-Dublin
Contact: Site Public Contact

Kaiser Permanente Dublin
Contact: Site Public Contact

El Segundo
21st Century Oncology - El Segundo
Contact: Site Public Contact

Emeryville
Bay Area Breast Surgeons Inc
Contact: Site Public Contact

Epic Care Partners in Cancer Care
Contact: Site Public Contact

Fremont
Kaiser Permanente-Fremont
Contact: Site Public Contact
Email: Kpoct@kp.org

Palo Alto Medical Foundation-Fremont
Contact: Site Public Contact
Email: bernicl@sutterhealth.org

Fresno
Fresno Cancer Center
Contact: Site Public Contact
Email: Kpoct@kp.org

Kaiser Permanente-Fresno
Contact: Site Public Contact
Email: Kpoct@kp.org

Los Angeles
Cedars Sinai Medical Center
Contact: Site Public Contact

Martinez
Contra Costa Regional Medical Center
Contact: Site Public Contact

Modesto
Kaiser Permanente-Modesto
Contact: Site Public Contact
Email: Kpoct@kp.org

Memorial Medical Center
Contact: Site Public Contact
Email: bernicl@sutterhealth.org

Mountain View
Palo Alto Medical Foundation-Camino Division
Contact: Site Public Contact
Email: bernicl@sutterhealth.org

Palo Alto Medical Foundation-Gynecologic Oncology
Contact: Site Public Contact
Email: bernicl@sutterhealth.org

Novato
Sutter Cancer Research Consortium
Contact: Site Public Contact
Email: bernicl@sutterhealth.org

Oakland
Alta Bates Summit Medical Center - Summit Campus
Contact: Site Public Contact

Bay Area Tumor Institute
Contact: Site Public Contact
Email: lradke@bati.org

Kaiser Permanente Oakland-Broadway
Contact: Site Public Contact
Email: Kpoct@kp.org

Kaiser Permanente-Oakland
Contact: Site Public Contact
Email: Kpoct@kp.org

Palo Alto
Palo Alto Medical Foundation Health Care
Contact: Site Public Contact
Email: bernicl@sutterhealth.org

Pomona
Pomona Valley Hospital Medical Center
Contact: Site Public Contact

Rancho Cordova
Kaiser Permanente-Rancho Cordova Cancer Center
Contact: Site Public Contact
Email: Kpoct@kp.org

Redwood City
Kaiser Permanente-Redwood City
Contact: Site Public Contact
Email: Kpoct@kp.org

Richmond
Kaiser Permanente-Richmond
Contact: Site Public Contact
Email: Kpoct@kp.org

Rohnert Park
Rohnert Park Cancer Center
Contact: Site Public Contact
Email: Kpoct@kp.org

Roseville
Kaiser Permanente-Roseville
Contact: Site Public Contact
Email: Kpoct@kp.org

Sutter Cancer Centers Radiation Oncology Services-Roseville
Contact: Site Public Contact
Email: bernicl@sutterhealth.org

Sutter Roseville Medical Center
Contact: Site Public Contact
Email: bernicl@sutterhealth.org

The Permanente Medical Group-Roseville Radiation Oncology
Contact: Site Public Contact
Email: Kpoct@kp.org

Sacramento
Kaiser Permanente - Sacramento
Contact: Site Public Contact
Email: Kpoct@kp.org

Kaiser Permanente Downtown Commons
Contact: Site Public Contact
Email: kpoct@kp.org

Kaiser Permanente-South Sacramento
Contact: Site Public Contact
Email: Kpoct@kp.org

South Sacramento Cancer Center
Contact: Site Public Contact
Email: Kpoct@kp.org

Sutter Medical Center Sacramento
Contact: Site Public Contact
Email: bernicl@sutterhealth.org

San Francisco
California Pacific Medical Center-Pacific Campus
Contact: Site Public Contact
Email: bernicl@sutterhealth.org

Kaiser Permanente-San Francisco
Contact: Site Public Contact
Email: Kpoct@kp.org

San Jose
Kaiser Permanente-Santa Teresa-San Jose
Contact: Site Public Contact
Email: Kpoct@kp.org

San Leandro
Kaiser Permanente San Leandro
Contact: Site Public Contact
Email: Kpoct@kp.org

San Luis Obispo
Pacific Central Coast Health Center-San Luis Obispo
Contact: Site Public Contact
Email: Diane.DeVos-Schmidt@DignityHealth.org

San Mateo
Mills Health Center
Contact: Site Public Contact
Email: ctsucontact@westat.com

San Rafael
Kaiser Permanente-San Rafael
Contact: Site Public Contact
Email: Kpoct@kp.org

Kaiser San Rafael-Gallinas
Contact: Site Public Contact
Email: Kpoct@kp.org

Santa Clara
Kaiser Permanente Medical Center - Santa Clara
Contact: Site Public Contact
Email: Kpoct@kp.org

Santa Cruz
Palo Alto Medical Foundation-Santa Cruz
Contact: Site Public Contact
Email: bernicl@sutterhealth.org

Santa Maria
Mission Hope Medical Oncology - Santa Maria
Contact: Site Public Contact
Email: research@dignityhealth.org

Santa Rosa
Kaiser Permanente-Santa Rosa
Contact: Site Public Contact
Email: Kpoct@kp.org

Sutter Pacific Medical Foundation
Contact: Site Public Contact
Email: bernicl@sutterhealth.org

South San Francisco
Kaiser Permanente Cancer Treatment Center
Contact: Site Public Contact
Email: Kpoct@kp.org

Kaiser Permanente-South San Francisco
Contact: Site Public Contact
Email: Kpoct@kp.org

Stockton
Kaiser Permanente-Stockton
Contact: Site Public Contact
Email: Kpoct@kp.org

Sunnyvale
Palo Alto Medical Foundation-Sunnyvale
Contact: Site Public Contact
Email: bernicl@sutterhealth.org

Vacaville
Kaiser Permanente Medical Center-Vacaville
Contact: Site Public Contact
Email: Kpoct@kp.org

Northbay Cancer Center
Contact: Site Public Contact

Sutter Cancer Centers Radiation Oncology Services-Vacaville
Contact: Site Public Contact
Email: bernicl@sutterhealth.org

Vallejo
Kaiser Permanente-Vallejo
Contact: Site Public Contact
Email: Kpoct@kp.org

Sutter Solano Medical Center/Cancer Center
Contact: Site Public Contact
Email: bernicl@sutterhealth.org

Walnut Creek
Epic Care Cyberknife Center
Contact: Site Public Contact
Email: somega@bati.org

Kaiser Permanente-Walnut Creek
Contact: Site Public Contact
Email: Kpoct@kp.org

Whittier
Presbyterian Intercommunity Hospital
Contact: Site Public Contact

CO
Aurora
Rocky Mountain Cancer Centers-Aurora
Contact: Site Public Contact
Email: info@westernstatesncorp.org

The Medical Center of Aurora
Contact: Site Public Contact
Email: info@westernstatesncorp.org

Boulder
Boulder Community Foothills Hospital
Contact: Site Public Contact
Email: info@westernstatesncorp.org

Boulder Community Hospital
Contact: Site Public Contact
Email: jbloomfield@co-cancerresearch.org

Rocky Mountain Cancer Centers-Boulder
Contact: Site Public Contact
Email: info@westernstatesncorp.org

Centennial
Rocky Mountain Cancer Centers - Centennial
Contact: Site Public Contact
Email: info@westernstatesncorp.org

Colorado Springs
Penrose-Saint Francis Healthcare
Contact: Site Public Contact
Email: clinicaltrials@sfmc-gi.org

Rocky Mountain Cancer Centers-Penrose
Contact: Site Public Contact
Email: info@westernstatesncorp.org

Denver
Cancer Center of Colorado at Sloan's Lake
Contact: Site Public Contact

Colorado Blood Cancer Institute
Contact: Site Public Contact
Email: info@westernstatesncorp.org

Denver Health Medical Center
Contact: Site Public Contact
Email: ccrp@co-cancerresearch.org

National Jewish Health-Main Campus
Contact: Site Public Contact
Email: glicht@co-cancerresearch.org

Porter Adventist Hospital
Contact: Site Public Contact
Email: clinicaltrials@sfmc-gi.org

Presbyterian - Saint Lukes Medical Center - Health One
Contact: Site Public Contact
Email: info@westernstatesncorp.org

Rocky Mountain Cancer Centers-Midtown
Contact: Site Public Contact
Email: info@westernstatesncorp.org

Rocky Mountain Cancer Centers-Rose
Contact: Site Public Contact
Email: info@westernstatesncorp.org

Rose Medical Center
Contact: Site Public Contact
Email: ccrp@co-cancerresearch.org

SCL Health Saint Joseph Hospital
Contact: Site Public Contact
Email: info@westernstatesncorp.org

The Women's Imaging Center
Contact: Site Public Contact
Email: info@westernstatesncorp.org

Durango
Mercy Medical Center
Contact: Site Public Contact
Email: clinicaltrials@sfmc-gi.org

Southwest Oncology PC
Contact: Site Public Contact
Email: clinicaltrials@sfmc-gi.org

Englewood
Mountain Blue Cancer Care Center - Swedish
Contact: Site Public Contact
Email: info@westernstatesncorp.org

Swedish Medical Center
Contact: Site Public Contact
Email: info@westernstatesncorp.org

Golden
Mountain Blue Cancer Care Center
Contact: Site Public Contact
Email: clinicaltrials@sfmc-gi.org

National Jewish Health-Western Hematology Oncology
Contact: Site Public Contact
Email: glicht@co-cancerresearch.org

Grand Junction
Grand Valley Oncology
Contact: Site Public Contact
Email: gvoclinicaltrials@gjhosp.org

Saint Mary's Hospital and Regional Medical Center
Contact: Site Public Contact
Email: ccrp@co-cancerresearch.org

Greeley
North Colorado Medical Center
Contact: Site Public Contact
Email: info@westernstatesncorp.org

Greenwood Village
Rocky Mountain Cancer Centers-Greenwood Village
Contact: Site Public Contact
Email: info@westernstatesncorp.org

Lafayette
Good Samaritan Medical Center
Contact: Site Public Contact

Lakewood
Rocky Mountain Cancer Centers-Lakewood
Contact: Site Public Contact
Email: info@westernstatesncorp.org

Saint Anthony Hospital
Contact: Site Public Contact
Email: clinicaltrials@sfmc-gi.org

Littleton
Littleton Adventist Hospital
Contact: Site Public Contact
Email: clinicaltrials@sfmc-gi.org

Rocky Mountain Cancer Centers-Littleton
Contact: Site Public Contact
Email: info@westernstatesncorp.org

Lone Tree
Rocky Mountain Cancer Centers-Sky Ridge
Contact: Site Public Contact
Email: info@westernstatesncorp.org

Sky Ridge Medical Center
Contact: Site Public Contact
Email: info@westernstatesncorp.org

Longmont
Longmont United Hospital
Contact: Site Public Contact
Email: clinicaltrials@sfmc-gi.org

Rocky Mountain Cancer Centers-Longmont
Contact: Site Public Contact
Email: info@westernstatesncorp.org

Loveland
McKee Medical Center
Contact: Site Public Contact
Email: info@westernstatesncorp.org

Parker
Parker Adventist Hospital
Contact: Site Public Contact
Email: clinicaltrials@sfmc-gi.org

Rocky Mountain Cancer Centers-Parker
Contact: Site Public Contact
Email: info@westernstatesncorp.org

Pueblo
Rocky Mountain Cancer Centers - Pueblo
Contact: Site Public Contact
Email: info@westernstatesncorp.org

Saint Mary Corwin Medical Center
Contact: Site Public Contact
Email: clinicaltrials@sfmc-gi.org

Thornton
National Jewish Health-Northern Hematology Oncology
Contact: Site Public Contact
Email: glicht@co-cancerresearch.org

Rocky Mountain Cancer Centers-Thornton
Contact: Site Public Contact
Email: info@westernstatesncorp.org

Wheat Ridge
SCL Health Lutheran Medical Center
Contact: Site Public Contact
Email: ccrp@co-cancerresearch.org

CT
Danbury
Danbury Hospital
Contact: Site Public Contact

Derby
Smilow Cancer Hospital-Derby Care Center
Contact: Site Public Contact
Email: canceranswers@yale.edu

Fairfield
Smilow Cancer Hospital Care Center-Fairfield
Contact: Site Public Contact
Email: canceranswers@yale.edu

Glastonbury
Smilow Cancer Hospital Care Center at Glastonbury
Contact: Site Public Contact
Email: canceranswers@yale.edu

Greenwich
Greenwich Hospital
Contact: Site Public Contact

Smilow Cancer Hospital Care Center at Greenwich
Contact: Site Public Contact
Email: canceranswers@yale.edu

Guilford
Smilow Cancer Hospital Care Center - Guiford
Contact: Site Public Contact
Email: canceranswers@yale.edu

Hartford
Smilow Cancer Hospital Care Center at Saint Francis
Contact: Site Public Contact
Email: canceranswers@yale.edu

New Haven
Yale University
Contact: Site Public Contact
Email: canceranswers@yale.edu

Yale-New Haven Hospital Saint Raphael Campus
Contact: Site Public Contact
Email: canceranswers@yale.edu

North Haven
Yale-New Haven Hospital North Haven Medical Center
Contact: Site Public Contact
Email: canceranswers@yale.edu

Norwalk
Norwalk Hospital
Contact: Site Public Contact
Email: jennifer.long@norwalkhealth.org

Orange
Smilow Cancer Hospital-Orange Care Center
Contact: Site Public Contact
Email: canceranswers@yale.edu

Torrington
Smilow Cancer Hospital-Torrington Care Center
Contact: Site Public Contact
Email: canceranswers@yale.edu

Trumbull
Smilow Cancer Hospital Care Center-Trumbull
Contact: Site Public Contact
Email: canceranswers@yale.edu

Waterbury
Smilow Cancer Hospital-Waterbury Care Center
Contact: Site Public Contact
Email: canceranswers@yale.edu

Waterford
Smilow Cancer Hospital Care Center - Waterford
Contact: Site Public Contact
Email: canceranswers@yale.edu

DC
Washington
Sibley Memorial Hospital
Contact: Site Public Contact
Email: jquiver1@jhmi.edu

DE
Frankford
Beebe South Coastal Health Campus
Contact: Site Public Contact
Email: Dmiskin@Beebehealthcare.org

Lewes
Beebe Medical Center
Contact: Site Public Contact
Email: Dmiskin@Beebehealthcare.org

Newark
Christiana Care Health System-Christiana Hospital
Contact: Site Public Contact
Email: mhayden@christianacare.org

Christiana Gynecologic Oncology LLC
Contact: Gregory Andrew Masters

Delaware Clinical and Laboratory Physicians PA
Contact: Site Public Contact
Email: mhayden@christianacare.org

Helen F Graham Cancer Center
Contact: Site Public Contact
Email: mhayden@christianacare.org

Medical Oncology Hematology Consultants PA
Contact: Site Public Contact
Email: mhayden@christianacare.org

Rehoboth Beach
Beebe Health Campus
Contact: Site Public Contact
Email: Dmiskin@Beebehealthcare.org

Seaford
TidalHealth Nanticoke / Allen Cancer Center
Contact: Site Public Contact
Email: anna-maria.howard@peninsula.org

Wilmington
Christiana Care Health System-Wilmington Hospital
Contact: Site Public Contact
Email: mhayden@christianacare.org

FL
Altamonte Springs
AdventHealth Altamonte
Contact: Site Public Contact

Aventura
GenesisCare USA - Aventura FP
Contact: Site Public Contact
Email: Rudi.Ross@usa.genesiscare.com

Boca Raton
GenesisCare USA - Boca Ration FP06
Contact: Site Public Contact
Email: Rudi.Ross@usa.genesiscare.com

GenesisCare USA - Boca Raton FP02
Contact: Site Public Contact
Email: Rudi.Ross@usa.genesiscare.com

Celebration
AdventHealth Celebration
Contact: Site Public Contact

Daytona Beach
Halifax Health Medical Center-Centers for Oncology
Contact: Site Public Contact

Fort Lauderdale
Holy Cross Hospital
Contact: Site Public Contact

Hollywood
Memorial Regional Hospital/Joe DiMaggio Children's Hospital
Contact: Site Public Contact
Email: OHR@mhs.net

Jacksonville
Baptist MD Anderson Cancer Center
Contact: Site Public Contact

Key West
GenesisCare USA - Key West
Contact: Site Public Contact
Email: Rudi.Ross@usa.genesiscare.com

Kissimmee
AdventHealth Kissimmee
Contact: Site Public Contact

Lakewood Ranch
GenesisCare USA - Lakewood Ranch
Contact: Site Public Contact
Email: Rudi.Ross@usa.genesiscare.com

Orlando
AdventHealth East Orlando
Contact: Site Public Contact

AdventHealth Medical Group Urology at Orlando
Contact: Site Public Contact

AdventHealth Orlando
Contact: Site Public Contact
Email: FH.Cancer.Research@flhosp.org

Ormond Beach
Halifax Health Center for Oncology - Ormond Beach
Contact: Site Public Contact
Email: debbie.reynolds@halifax.org

Palm Beach Gardens
GenesisCare USA - Palm Beach Gardens
Contact: Site Public Contact
Email: Rudi.Ross@usa.genesiscare.com

Pembroke Pines
Memorial Hospital West
Contact: Site Public Contact

Plantation
GenesisCare USA - Plantation
Contact: Site Public Contact
Email: Rudi.Ross@usa.genesiscare.com

Port Orange
Halifax Health Center for Oncology - Port Orange
Contact: Site Public Contact
Email: debbie.reynolds@halifax.org

West Palm Beach
Good Samaritan Medical Center
Contact: Site Public Contact

Winter Park
AdventHealth Winter Park
Contact: Site Public Contact

GA
Albany
Phoebe Putney Memorial Hospital
Contact: Site Public Contact
Email: ga_cares@augusta.edu

Athens
University Cancer and Blood Center LLC
Contact: Site Public Contact
Email: research@universitycancer.com

Atlanta
Emory Saint Joseph's Hospital
Contact: Site Public Contact

Emory University Hospital Midtown
Contact: Site Public Contact

Emory University Hospital/Winship Cancer Institute
Contact: Site Public Contact

Grady Health System
Contact: Site Public Contact

Northside Hospital
Contact: Site Public Contact
Email: ClinicalTrials@northside.com

Augusta
Augusta Oncology Associates PC-D'Antignac
Contact: Site Public Contact

Augusta Oncology Associates PC-Wheeler
Contact: Site Public Contact

Cumming
Northside Hospital-Forsyth
Contact: Site Public Contact
Email: clinicaltrials@northside.com

Decatur
Dekalb Medical Center
Contact: Site Public Contact
Email: clinicaltrialsoncology@dekalbmedical.org

Macon
Central Georgia Gynecologic Oncology
Contact: Site Public Contact

Medical Center of Central Georgia
Contact: Site Public Contact
Email: weatherall.andrew@navicenthealth.org

Savannah
Lewis Cancer and Research Pavilion at Saint Joseph's/Candler
Contact: Site Public Contact
Email: underberga@sjchs.org

Low Country Cancer Care
Contact: Site Public Contact

Summit Cancer Care-Candler
Contact: Site Public Contact
Email: ecog.rss@jimmy.harvard.edu

Valdosta
South Georgia Medical Center/Pearlman Cancer Center
Contact: Site Public Contact
Email: maryann.heddon@sgmc.org

GU
Tamuning
FHP Health Center-Guam
Contact: Site Public Contact

HI
Aiea
Hawaii Cancer Care - Savio
Contact: Site Public Contact

Pali Momi Medical Center
Contact: Site Public Contact

Queen's Cancer Center - Pearlridge
Contact: Site Public Contact

The Cancer Center of Hawaii-Pali Momi
Contact: Site Public Contact

Ewa Beach
The Queen's Medical Center - West Oahu
Contact: Site Public Contact
Email: rohta@queens.org

Honolulu
Hawaii Cancer Care Inc - Waterfront Plaza
Contact: Site Public Contact
Email: i.webster@hawaiicancercare.com

Hawaii Cancer Care Inc-Liliha
Contact: Site Public Contact

Hawaii Diagnostic Radiology Services LLC
Contact: Site Public Contact
Email: mmiyoshi@hawaiidrs.com

Island Urology
Contact: Site Public Contact
Email: virginia@cc.hawaii.edu

Kaiser Permanente Moanalua Medical Center
Contact: Site Public Contact
Email: shelley.a.clark@kp.org

Kapiolani Medical Center for Women and Children
Contact: Site Public Contact

Kuakini Medical Center
Contact: Site Public Contact

Queen's Cancer Cenrer - POB I
Contact: Site Public Contact

Queen's Cancer Center - Kuakini
Contact: Site Public Contact

Queen's Medical Center
Contact: Site Public Contact

Straub Clinic and Hospital
Contact: Site Public Contact

The Cancer Center of Hawaii-Liliha
Contact: Site Public Contact

University of Hawaii Cancer Center
Contact: Site Public Contact

Lihue
Wilcox Memorial Hospital and Kauai Medical Clinic
Contact: Site Public Contact

IA
Ames
Mary Greeley Medical Center
Contact: Site Public Contact

McFarland Clinic PC - Ames
Contact: Site Public Contact
Email: ksoder@mcfarlandclinic.com

Bettendorf
Constantinou, Costas L MD (UIA Investigator)
Contact: Site Public Contact

Boone
McFarland Clinic PC-Boone
Contact: Site Public Contact

Cedar Rapids
Mercy Hospital
Contact: Site Public Contact

Oncology Associates at Mercy Medical Center
Contact: Site Public Contact

Clive
Medical Oncology and Hematology Associates-West Des Moines
Contact: Site Public Contact
Email: clinicaltrials@sfmc-gi.org

Mercy Cancer Center-West Lakes
Contact: Site Public Contact
Email: clinicaltrials@sfmc-gi.org

Council Bluffs
Alegent Health Mercy Hospital
Contact: Site Public Contact
Email: clinicaltrials@sfmc-gi.org

Creston
Greater Regional Medical Center
Contact: Site Public Contact
Email: clinicaltrials@sfmc-gi.org

Davenport
Genesis Cancer Care Institute
Contact: Site Public Contact
Email: turnerk@genesishealth.com

Genesis Medical Center - East Campus
Contact: Site Public Contact
Email: turnerk@genesishealth.com

Iowa Cancer Specialists
Contact: Site Public Contact
Email: turnerk@genesishealth.com

Des Moines
Broadlawns Medical Center
Contact: Site Public Contact

Iowa Lutheran Hospital
Contact: Site Public Contact

Iowa Methodist Medical Center
Contact: Site Public Contact

Medical Oncology and Hematology Associates-Des Moines
Contact: Site Public Contact

Mercy Medical Center - Des Moines
Contact: Site Public Contact
Email: clinicaltrials@sfmc-gi.org

Mission Cancer and Blood - Laurel
Contact: Site Public Contact
Email: clinicaltrials@sfmc-gi.org

Fairfield
JCHC McCreery Cancer Center
Contact: Site Public Contact

Fort Dodge
McFarland Clinic PC-Trinity Cancer Center
Contact: Site Public Contact

Trinity Regional Medical Center
Contact: Site Public Contact

Jefferson
McFarland Clinic PC-Jefferson
Contact: Site Public Contact

Marshalltown
McFarland Clinic PC-Marshalltown
Contact: Site Public Contact

Ottumwa
Ottumwa Regional Health Center
Contact: Site Public Contact

Sioux City
Siouxland Regional Cancer Center
Contact: Site Public Contact
Email: HoopingarnerT@jencc.com

West Des Moines
Mercy Medical Center-West Lakes
Contact: Site Public Contact
Email: clinicaltrials@sfmc-gi.org

Methodist West Hospital
Contact: Site Public Contact

ID
Boise
Saint Alphonsus Cancer Care Center-Boise
Contact: Site Public Contact
Email: stephanie.couch@stjoeshealth.org

Saint Luke's Cancer Institute - Boise
Contact: Site Public Contact
Email: eslinget@slhs.org

Caldwell
Saint Alphonsus Cancer Care Center-Caldwell
Contact: Site Public Contact
Email: stephanie.couch@stjoeshealth.org

Coeur D'Alene
Kootenai Health - Coeur d'Alene
Contact: Site Public Contact
Email: mccinfo@mtcancer.org

Emmett
Walter Knox Memorial Hospital
Contact: Site Public Contact
Email: stephanie.couch@stjoeshealth.org

Fruitland
Saint Luke's Cancer Institute - Fruitland
Contact: Site Public Contact
Email: eslinget@slhs.org

Meridian
Idaho Urologic Institute-Meridian
Contact: Site Public Contact
Email: stephanie.couch@stjoeshealth.org

Saint Luke's Cancer Institute - Meridian
Contact: Site Public Contact
Email: eslinget@slhs.org

Nampa
Saint Alphonsus Medical Center-Nampa
Contact: Site Public Contact
Email: stephanie.couch@stjoeshealth.org

Saint Luke's Cancer Institute - Nampa
Contact: Site Public Contact
Email: eslinget@slhs.org

Post Falls
Kootenai Clinic Cancer Services - Post Falls
Contact: Site Public Contact
Email: mccinfo@mtcancer.org

Sandpoint
Kootenai Cancer Clinic
Contact: Site Public Contact
Email: mccinfo@mtcancer.org

Twin Falls
Saint Luke's Cancer Institute - Twin Falls
Contact: Site Public Contact
Email: eslinget@slhs.org

IL
Aurora
Rush - Copley Medical Center
Contact: Site Public Contact
Email: Cancer.Research@rushcopley.com

Bloomington
Illinois CancerCare-Bloomington
Contact: Site Public Contact
Email: andersonj@illinoiscancercare.com

Saint Joseph Medical Center
Contact: Site Public Contact
Email: andersonj@illinoiscancercare.com

Canton
Illinois CancerCare-Canton
Contact: Site Public Contact
Email: andersonj@illinoiscancercare.com

Carbondale
Memorial Hospital of Carbondale
Contact: Site Public Contact
Email: clinical.research@sih.net

Carterville
SIH Cancer Institute
Contact: Site Public Contact
Email: clinical.research@sih.net

Carthage
Illinois CancerCare-Carthage
Contact: Site Public Contact
Email: andersonj@illinoiscancercare.com

Centralia
Centralia Oncology Clinic
Contact: Site Public Contact
Email: rhamrick@dmhhs.org

Chicago
John H Stroger Jr Hospital of Cook County
Contact: Site Public Contact

Northwestern University
Contact: Site Public Contact
Email: cancer@northwestern.edu

Swedish Covenant Hospital
Contact: Site Public Contact

Crystal Lake
AMG Crystal Lake - Oncology
Contact: Site Public Contact
Email: advocateresearch@advocate.com

Danville
Carle on Vermilion
Contact: Site Public Contact
Email: Research@carle.com

Decatur
Cancer Care Specialists of Illinois - Decatur
Contact: Site Public Contact
Email: rhamrick@dmhhs.org

Decatur Memorial Hospital
Contact: Site Public Contact
Email: rhamrick@dmhhs.org

Dixon
Illinois CancerCare-Dixon
Contact: Site Public Contact

Effingham
Carle Physician Group-Effingham
Contact: Site Public Contact
Email: Research@carle.com

Crossroads Cancer Center
Contact: Site Public Contact
Email: rhamrick@dmhhs.org

Eureka
Illinois CancerCare-Eureka
Contact: Site Public Contact
Email: andersonj@illinoiscancercare.com

Evanston
NorthShore University HealthSystem-Evanston Hospital
Contact: Site Public Contact

Saint Francis Hospital
Contact: Site Public Contact

Galesburg
Illinois CancerCare-Galesburg
Contact: Site Public Contact
Email: andersonj@illinoiscancercare.com

Western Illinois Cancer Treatment Center
Contact: Site Public Contact

Glenview
NorthShore University HealthSystem-Glenbrook Hospital
Contact: Site Public Contact

Harvey
Ingalls Memorial Hospital
Contact: Site Public Contact
Email: clinicaltrials@ingalls.org

Highland Park
Hematology Oncology Associates of Illinois-Highland Park
Contact: Site Public Contact

NorthShore University HealthSystem-Highland Park Hospital
Contact: Site Public Contact

Kewanee
Illinois CancerCare-Kewanee Clinic
Contact: Site Public Contact
Email: andersonj@illinoiscancercare.com

Lake Forest
Northwestern Medicine Lake Forest Hospital
Contact: Site Public Contact
Email: cancertrials@northwestern.edu

Libertyville
AMG Libertyville - Oncology
Contact: Site Public Contact
Email: advocateresearch@advocatehealth.com

Macomb
Illinois CancerCare-Macomb
Contact: Site Public Contact
Email: andersonj@illinoiscancercare.com

Mattoon
Carle Physician Group-Mattoon/Charleston
Contact: Site Public Contact
Email: Research@carle.com

Moline
Garneau, Stewart C MD (UIA Investigator)
Contact: Site Public Contact

Spector, David MD (UIA Investigator)
Contact: Site Public Contact

Trinity Medical Center
Contact: Site Public Contact

Mount Vernon
Good Samaritan Regional Health Center
Contact: Site Public Contact

Niles
Illinois Cancer Specialists-Niles
Contact: Site Public Contact

O'Fallon
Cancer Care Center of O'Fallon
Contact: Site Public Contact
Email: morganthaler.jodi@mhsil.com

Oak Lawn
Advocate Christ Medical Center
Contact: Site Public Contact

Ottawa
Illinois CancerCare-Ottawa Clinic
Contact: Site Public Contact
Email: andersonj@illinoiscancercare.com

Radiation Oncology of Northern Illinois
Contact: Site Public Contact
Email: andersonj@illinoiscancercare.com

Pekin
Illinois CancerCare-Pekin
Contact: Site Public Contact
Email: andersonj@illinoiscancercare.com

OSF Saint Francis Radiation Oncology at Pekin Cancer Treatment Center
Contact: Site Public Contact
Email: andersonj@illinoiscancercare.com

Peoria
Illinois CancerCare-Peoria
Contact: Site Public Contact
Email: andersonj@illinoiscancercare.com

Methodist Medical Center of Illinois
Contact: Site Public Contact
Email: andersonj@illinoiscancercare.com

OSF Saint Francis Medical Center
Contact: Site Public Contact
Email: andersonj@illinoiscancercare.com

OSF Saint Francis Radiation Oncology at Peoria Cancer Center
Contact: Site Public Contact
Email: andersonj@illinoiscancercare.com

Peru
Illinois CancerCare-Peru
Contact: Site Public Contact
Email: andersonj@illinoiscancercare.com

Valley Radiation Oncology
Contact: Site Public Contact

Princeton
Illinois CancerCare-Princeton
Contact: Site Public Contact
Email: andersonj@illinoiscancercare.com

River Forest
West Suburban Medical Center
Contact: Site Public Contact

Rockford
SwedishAmerican Regional Cancer Center/ACT
Contact: Site Public Contact
Email: cancercare@swedishamerican.org

Silvis
Genesis Cancer Center - Silvis
Contact: Site Public Contact
Email: turnerk@genesishealth.com

Skokie
Hematology Oncology Associates of Illinois - Skokie
Contact: Site Public Contact
Email: info@orchardhr.com

North Shore Medical Center
Contact: Site Public Contact
Email: ecog.rss@jimmy.harvard.edu

Springfield
Central Illinois Hematology Oncology Center
Contact: Site Public Contact

Memorial Medical Center
Contact: Site Public Contact

Southern Illinois University School of Medicine
Contact: Site Public Contact

Springfield Clinic
Contact: Site Public Contact

Swansea
Southwest Illinois Health Services LLP
Contact: Site Public Contact
Email: lynns@thecancercenter.com

Urbana
Carle Cancer Center
Contact: Site Public Contact
Email: Research@carle.com

The Carle Foundation Hospital
Contact: Site Public Contact
Email: Research@carle.com

Yorkville
Rush-Copley Healthcare Center
Contact: Site Public Contact
Email: Cancer.Research@rushcopley.com

IN
Carmel
IU Health North Hospital
Contact: Site Public Contact
Email: iutrials@iu.edu

Evansville
Deaconess Clinic Downtown
Contact: Site Public Contact
Email: Research@Deaconess.com

Indianapolis
Ascension Saint Vincent Indianapolis Hospital
Contact: Site Public Contact
Email: research@stvincent.org

Indiana University/Melvin and Bren Simon Cancer Center
Contact: Site Public Contact
Email: iutrials@iu.edu

Sidney and Lois Eskenazi Hospital
Contact: Site Public Contact
Email: iutrials@iu.edu

Springmill Medical Center
Contact: Site Public Contact
Email: iutrials@iu.edu

Michigan City
Franciscan Saint Anthony Health-Michigan City
Contact: Site Public Contact

Woodland Cancer Care Center
Contact: Site Public Contact
Email: sally.arnett@franciscanalliance.org

Mishawaka
Memorial Regional Cancer Center Day Road
Contact: Site Public Contact
Email: ctsucontact@westat.com

Munster
The Community Hospital
Contact: Site Public Contact

Newburgh
Chancellor Center for Oncology
Contact: Site Public Contact
Email: Research@Deaconess.com

Richmond
Reid Health
Contact: Site Public Contact
Email: clinical.trials@daytonncorp.org

South Bend
Memorial Hospital of South Bend
Contact: Site Public Contact

KS
Chanute
Cancer Center of Kansas - Chanute
Contact: Site Public Contact
Email: Keisha.humphries@ascension.org

Dodge City
Cancer Center of Kansas - Dodge City
Contact: Site Public Contact
Email: Keisha.humphries@ascension.org

El Dorado
Cancer Center of Kansas - El Dorado
Contact: Site Public Contact
Email: Keisha.humphries@ascension.org

Fort Scott
Cancer Center of Kansas - Fort Scott
Contact: Site Public Contact
Email: Keisha.humphries@ascension.org

Garden City
Central Care Cancer Center - Garden City
Contact: Site Public Contact
Email: aroland@kccop.org

Great Bend
Central Care Cancer Center - Great Bend
Contact: Site Public Contact
Email: aroland@kccop.org

Independence
Cancer Center of Kansas-Independence
Contact: Site Public Contact
Email: Keisha.humphries@ascension.org

Kingman
Cancer Center of Kansas-Kingman
Contact: Site Public Contact
Email: Keisha.humphries@ascension.org

Lawrence
Lawrence Memorial Hospital
Contact: Site Public Contact
Email: Stephanie.Norris@LMH.ORG

Lenexa
Kansas Institute of Medicine Cancer and Blood Center
Contact: Site Public Contact
Email: aroland@kccop.org

Minimally Invasive Surgery Hospital
Contact: Site Public Contact
Email: aroland@kccop.org

Liberal
Cancer Center of Kansas-Liberal
Contact: Site Public Contact
Email: Keisha.humphries@ascension.org

Manhattan
Cancer Center of Kansas-Manhattan
Contact: Site Public Contact
Email: Keisha.humphries@ascension.org

McPherson
Cancer Center of Kansas - McPherson
Contact: Site Public Contact
Email: Keisha.humphries@ascension.org

Newton
Cancer Center of Kansas - Newton
Contact: Site Public Contact
Email: Keisha.humphries@ascension.org

Overland Park
Menorah Medical Center
Contact: Site Public Contact
Email: aroland@kccop.org

Saint Luke's South Hospital
Contact: Site Public Contact
Email: aroland@kccop.org

Parsons
Cancer Center of Kansas - Parsons
Contact: Site Public Contact
Email: Keisha.humphries@ascension.org

Pratt
Cancer Center of Kansas - Pratt
Contact: Site Public Contact
Email: Keisha.humphries@ascension.org

Salina
Cancer Center of Kansas - Salina
Contact: Site Public Contact
Email: Keisha.humphries@ascension.org

Wellington
Cancer Center of Kansas - Wellington
Contact: Site Public Contact
Email: Keisha.humphries@ascension.org

Wichita
Ascension Via Christi Hospitals Wichita
Contact: Site Public Contact
Email: Keisha.humphries@ascension.org

Associates In Womens Health
Contact: Site Public Contact
Email: Keisha.humphries@ascension.org

Cancer Center of Kansas - Wichita
Contact: Site Public Contact
Email: Keisha.humphries@ascension.org

Cancer Center of Kansas-Wichita Medical Arts Tower
Contact: Site Public Contact
Email: Keisha.humphries@ascension.org

Winfield
Cancer Center of Kansas - Winfield
Contact: Site Public Contact
Email: Keisha.humphries@ascension.org

KY
Bardstown
Flaget Memorial Hospital
Contact: Site Public Contact
Email: clinicaltrials@sfmc-gi.org

Corbin
Commonwealth Cancer Center-Corbin
Contact: Site Public Contact
Email: clinicaltrials@sfmc-gi.org

Crestview Hills
Oncology Hematology Care Inc-Crestview
Contact: Site Public Contact
Email: clinical.trials@daytonncorp.org

Edgewood
Saint Elizabeth Healthcare Edgewood
Contact: Site Public Contact
Email: gina.kavanaugh@stelizabeth.com

Fort Thomas
Saint Elizabeth Fort Thomas
Contact: Site Public Contact
Email: gina.kavanaugh@stelizabeth.com

Lexington
Saint Joseph Hospital East
Contact: Site Public Contact
Email: clinicaltrials@sfmc-gi.org

Saint Joseph Radiation Oncology Resource Center
Contact: Site Public Contact
Email: clinicaltrials@sfmc-gi.org

University of Kentucky/Markey Cancer Center
Contact: Site Public Contact

London
Saint Joseph London
Contact: Site Public Contact
Email: clinicaltrials@sfmc-gi.org

Louisville
Jewish Hospital
Contact: Site Public Contact
Email: clinicaltrials@sfmc-gi.org

Saints Mary and Elizabeth Hospital
Contact: Site Public Contact
Email: clinicaltrials@sfmc-gi.org

UofL Health Medical Center Northeast
Contact: Site Public Contact
Email: clinicaltrials@sfmc-gi.org

Shepherdsville
Jewish Hospital Medical Center South
Contact: Site Public Contact
Email: clinicaltrials@sfmc-gi.org

LA
Alexandria
Christus Saint Frances Cabrini Hospital
Contact: Site Public Contact
Email: tammy.debona@christushealth.org

Baton Rouge
LSU Health Baton Rouge-North Clinic
Contact: Site Public Contact
Email: clinicalresearch@marybird.com

Louisiana Hematology Oncology Associates LLC
Contact: Site Public Contact
Email: clinicalresearch@marybird.com

Mary Bird Perkins Cancer Center
Contact: Site Public Contact
Email: clinicalresearch@marybird.com

Medical Center of Baton Rouge
Contact: Site Public Contact
Email: Camille.Beck@Ochsner.org

Ochsner Health Center-Summa
Contact: Site Public Contact
Email: Camille.Beck@Ochsner.org

Ochsner High Grove
Contact: Site Public Contact
Email: Gregory.Johnstone@ochsner.org

Our Lady of the Lake Physicians Group - Medical Oncology
Contact: Site Public Contact
Email: clinicalresearch@marybird.com

Covington
Northshore Oncology Associates-Covington
Contact: Site Public Contact
Email: clinicalresearch@marybird.com

Ochsner Hematology Oncology North Shore - Covington (West Region)
Contact: Site Public Contact
Email: Gregory.Johnstone@ochsner.org

Houma
Oncology Center of The South Incorporated
Contact: Site Public Contact
Email: clinicalresearch@marybird.com

Terrebonne General Medical Center
Contact: Site Public Contact
Email: ann.hooks@tgmc.com

Kenner
Ochsner Medical Center Kenner
Contact: Site Public Contact
Email: cris.molina@ochsner.org

Lake Charles
CHRISTUS Lake Charles Medical Center
Contact: Site Public Contact
Email: laura.smith2@christushealth.org

Metairie
East Jefferson General Hospital
Contact: Site Public Contact
Email: emede1@lsuhsc.edu

Monroe
Ochsner LSU Health Monroe Medical Center
Contact: Site Public Contact
Email: LPost@lsuhsc.edu

New Orleans
Louisiana State University Health Science Center
Contact: Site Public Contact
Email: emede1@lsuhsc.edu

Ochsner Baptist Medical Center
Contact: Site Public Contact
Email: Gregory.Johnstone@ochsner.org

Ochsner Medical Center Jefferson
Contact: Site Public Contact
Email: Gregory.Johnstone@ochsner.org

University Medical Center New Orleans
Contact: Site Public Contact
Email: emede1@lsuhsc.edu

Shreveport
CHRISTUS Highland Medical Center
Contact: Site Public Contact
Email: Nancy.hassan@christushealth.org

LSU Health Sciences Center at Shreveport
Contact: Site Public Contact
Email: LPost@lsuhsc.edu

Ochsner LSU Health Saint Mary's Medical Center
Contact: Site Public Contact
Email: LPost@lsuhsc.edu

Slidell
Ochsner Hematology Oncology North Shore - Slidell (East Region)
Contact: Site Public Contact
Email: Gregory.Johnstone@ochsner.org

Saint Tammany Hospital Service District #2 / Slidell Memorial Hospital
Contact: Site Public Contact
Email: Gregory.Johnstone@ochsner.org

MA
Beverly
Beverly Hospital
Contact: Site Public Contact

Boston
Beth Israel Deaconess Medical Center
Contact: Site Public Contact

Dana-Farber Cancer Institute
Contact: Site Public Contact

Burlington
Lahey Hospital and Medical Center
Contact: Site Public Contact
Email: cancerclinicaltrials@lahey.org

Gloucester
Addison Gilbert Hospital
Contact: Site Public Contact

Lowell
Lowell General Hospital
Contact: Site Public Contact
Email: ghincks@lowellgeneral.org

Milford
Dana-Farber/Brigham and Women's Cancer Center at Milford Regional
Contact: Site Public Contact

Newton
Newton-Wellesley Hospital
Contact: Site Public Contact

Peabody
Lahey Medical Center-Peabody
Contact: Site Public Contact
Email: ctsucontact@westat.com

Plymouth
Beth Israel Deaconess Hospital-Plymouth
Contact: Site Public Contact
Email: cancerinfo@jordanhospital.org

South Weymouth
Dana-Farber/Brigham and Women's Cancer Center at South Shore
Contact: Site Public Contact

Springfield
Mercy Medical Center
Contact: Site Public Contact

Winchester
Winchester Hospital
Contact: Site Public Contact
Email: ctsucontact@westat.com

Worcester
UMass Memorial Medical Center - University Campus
Contact: Site Public Contact
Email: cancer.research@umassmed.edu

MD
Baltimore
Greater Baltimore Medical Center
Contact: Site Public Contact

Johns Hopkins University/Sidney Kimmel Cancer Center
Contact: Site Public Contact
Email: jhcccro@jhmi.edu

Mercy Medical Center
Contact: Site Public Contact
Email: acline@mdmercy.com

Sinai Hospital of Baltimore
Contact: Site Public Contact
Email: pridgely@lifebridgehealth.org

Frederick
FMH James M Stockman Cancer Institute
Contact: Site Public Contact

Frederick Memorial Hospital
Contact: Site Public Contact
Email: clinicaltrials@fmh.org

Ocean Pines
TidalHealth Richard A Henson Cancer Institute
Contact: Site Public Contact
Email: carol.messick@peninsula.org

Randallstown
Northwest Hospital Center
Contact: Site Public Contact
Email: cancerinstitute@lifebridgehealth.org

Salisbury
TidalHealth Peninsula Regional
Contact: Site Public Contact
Email: monika.naegeli@peninsula.org

Silver Spring
Holy Cross Hospital
Contact: Site Public Contact

Westminster
William E Kahlert Regional Cancer Center/Sinai Hospital
Contact: Site Public Contact

ME
Augusta
Harold Alfond Center for Cancer Care
Contact: Site Public Contact

Bangor
Eastern Maine Medical Center
Contact: Site Public Contact

Brewer
Lafayette Family Cancer Center-EMMC
Contact: Site Public Contact

Rockport
Penobscot Bay Medical Center
Contact: Site Public Contact
Email: ClinicalResearch@mmc.org

MI
Adrian
Hickman Cancer Center
Contact: Site Public Contact

Ann Arbor
Saint Joseph Mercy Hospital
Contact: Site Public Contact
Email: stephanie.couch@stjoeshealth.org

Battle Creek
Bronson Battle Creek
Contact: Site Public Contact
Email: crcwm-regulatory@crcwm.org

Bay City
McLaren Cancer Institute-Bay City
Contact: Site Public Contact
Email: ctoadmin@karmanos.org

Bloomfield
McLaren Cancer Institute-Bloomfield
Contact: Site Public Contact
Email: ctoadmin@karmanos.org

Brighton
Saint Joseph Mercy Brighton
Contact: Site Public Contact
Email: stephanie.couch@stjoeshealth.org

Trinity Health IHA Medical Group Hematology Oncology - Brighton
Contact: Site Public Contact
Email: stephanie.couch@stjoeshealth.org

Brownstown
Henry Ford Cancer Institute-Downriver
Contact: Site Public Contact
Email: CTOResearch@hfhs.org

Canton
Saint Joseph Mercy Canton
Contact: Site Public Contact
Email: stephanie.couch@stjoeshealth.org

Trinity Health IHA Medical Group Hematology Oncology - Canton
Contact: Site Public Contact
Email: stephanie.couch@stjoeshealth.org

Caro
Caro Cancer Center
Contact: Site Public Contact
Email: stephanie.couch@stjoeshealth.org

Chelsea
Saint Joseph Mercy Chelsea
Contact: Site Public Contact
Email: stephanie.couch@stjoeshealth.org

Trinity Health IHA Medical Group Hematology Oncology - Chelsea Hospital
Contact: Site Public Contact
Email: stephanie.couch@stjoeshealth.org

Clarkston
GenesisCare USA - Clarkston
Contact: Site Public Contact
Email: Rudi.Ross@usa.genesiscare.com

Hematology Oncology Consultants-Clarkston
Contact: Site Public Contact
Email: stephanie.couch@stjoeshealth.org

McLaren Cancer Institute-Clarkston
Contact: Site Public Contact
Email: ctoadmin@karmanos.org

Newland Medical Associates-Clarkston
Contact: Site Public Contact
Email: stephanie.couch@stjoeshealth.org

Clinton Township
Henry Ford Macomb Hospital-Clinton Township
Contact: Site Public Contact
Email: CTOResearch@hfhs.org

Dearborn
Beaumont Hospital - Dearborn
Contact: Site Public Contact

Henry Ford Medical Center-Fairlane
Contact: Site Public Contact
Email: CTOResearch@hfhs.org

Detroit
Ascension Saint John Hospital
Contact: Site Public Contact
Email: stephanie.couch@stjoeshealth.org

Henry Ford Hospital
Contact: Site Public Contact
Email: CTOResearch@hfhs.org

Wayne State University/Karmanos Cancer Institute
Contact: Site Public Contact
Email: ctoadmin@karmanos.org

East China
Great Lakes Cancer Management Specialists-Doctors Park
Contact: Site Public Contact
Email: stephanie.couch@stjoeshealth.org

Escanaba
Green Bay Oncology - Escanaba
Contact: Site Public Contact
Email: ewd_research_admin@hshs.org

Farmington Hills
Beaumont Hospital - Farmington Hills
Contact: Site Public Contact

GenesisCare USA - Farmington Hills
Contact: Site Public Contact
Email: Rudi.Ross@usa.genesiscare.com

Weisberg Cancer Treatment Center
Contact: Site Public Contact
Email: ctoadmin@karmanos.org

Flint
Genesee Cancer and Blood Disease Treatment Center
Contact: Site Public Contact
Email: stephanie.couch@stjoeshealth.org

Genesee Hematology Oncology PC
Contact: Site Public Contact
Email: stephanie.couch@stjoeshealth.org

Genesys Hurley Cancer Institute
Contact: Site Public Contact
Email: stephanie.couch@stjoeshealth.org

Hurley Medical Center
Contact: Site Public Contact
Email: stephanie.couch@stjoeshealth.org

McLaren Cancer Institute-Flint
Contact: Site Public Contact
Email: ctoadmin@karmanos.org

Grand Rapids
Helen DeVos Children's Hospital at Spectrum Health
Contact: Site Public Contact
Email: crcwm-regulatory@crcwm.org

Spectrum Health at Butterworth Campus
Contact: Site Public Contact
Email: crcwm-regulatory@crcwm.org

Trinity Health Grand Rapids Hospital
Contact: Site Public Contact
Email: crcwm-regulatory@crcwm.org

Grosse Pointe
William Beaumont Hospital-Grosse Pointe
Contact: Site Public Contact

Grosse Pointe Woods
Academic Hematology Oncology Specialists
Contact: Site Public Contact
Email: stephanie.couch@stjoeshealth.org

Great Lakes Cancer Management Specialists-Van Elslander Cancer Center
Contact: Site Public Contact
Email: stephanie.couch@stjoeshealth.org

Michigan Breast Specialists-Grosse Pointe Woods
Contact: Site Public Contact
Email: stephanie.couch@stjoeshealth.org

Jackson
Allegiance Health
Contact: Site Public Contact
Email: CTOResearch@hfhs.org

Kalamazoo
Borgess Medical Center
Contact: Site Public Contact
Email: crcwm-regulatory@crcwm.org

Bronson Methodist Hospital
Contact: Site Public Contact
Email: crcwm-regulatory@crcwm.org

West Michigan Cancer Center
Contact: Site Public Contact
Email: crcwm-regulatory@crcwm.org

Lansing
Karmanos Cancer Institute at McLaren Greater Lansing
Contact: Site Public Contact
Email: ctoadmin@karmanos.org

Mid-Michigan Physicians-Lansing
Contact: Site Public Contact
Email: ctoadmin@karmanos.org

Sparrow Hospital
Contact: Site Public Contact
Email: stephanie.couch@stjoeshealth.org

Lapeer
McLaren Cancer Institute-Lapeer Region
Contact: Site Public Contact
Email: ctoadmin@karmanos.org

Livonia
Hope Cancer Clinic
Contact: Site Public Contact
Email: stephanie.couch@stjoeshealth.org

Trinity Health Saint Mary Mercy Livonia Hospital
Contact: Site Public Contact
Email: stephanie.couch@stjoeshealth.org

Macomb
GenesisCare USA - Macomb
Contact: Site Public Contact
Email: Rudi.Ross@usa.genesiscare.com

Macomb Township
Great Lakes Cancer Management Specialists-Macomb Medical Campus
Contact: Site Public Contact
Email: stephanie.couch@stjoeshealth.org

Michigan Breast Specialists-Macomb Township
Contact: Site Public Contact
Email: stephanie.couch@stjoeshealth.org

Madison Heights
GenesisCare USA - Madison Heights
Contact: Site Public Contact
Email: Rudi.Ross@usa.genesiscare.com

Marlette
Saint Mary's Oncology/Hematology Associates of Marlette
Contact: Site Public Contact
Email: stephanie.couch@stjoeshealth.org

Monroe
Monroe Cancer Center
Contact: Site Public Contact
Email: ctsucontact@westat.com

Toledo Clinic Cancer Centers-Monroe
Contact: Site Public Contact

Mount Clemens
McLaren Cancer Institute-Macomb
Contact: Site Public Contact
Email: ctoadmin@karmanos.org

Mount Pleasant
McLaren Cancer Institute-Central Michigan
Contact: Site Public Contact
Email: ctoadmin@karmanos.org

Muskegon
Trinity Health Muskegon Hospital
Contact: Site Public Contact
Email: crcwm-regulatory@crcwm.org

Niles
Lakeland Hospital Niles
Contact: Site Public Contact

Norton Shores
Cancer and Hematology Centers of Western Michigan - Norton Shores
Contact: Site Public Contact
Email: connie.szczepanek@crcwm.org

Novi
Ascension Providence Hospitals - Novi
Contact: Site Public Contact
Email: karen.fife@ascension.org

Henry Ford Medical Center-Columbus
Contact: Site Public Contact
Email: CTOResearch@hfhs.org

Petoskey
McLaren Cancer Institute-Northern Michigan
Contact: Site Public Contact
Email: ctoadmin@karmanos.org

Pontiac
21st Century Oncology-Pontiac
Contact: Site Public Contact
Email: stephanie.couch@stjoeshealth.org

Hope Cancer Center
Contact: Site Public Contact
Email: stephanie.couch@stjoeshealth.org

Newland Medical Associates-Pontiac
Contact: Site Public Contact
Email: stephanie.couch@stjoeshealth.org

Saint Joseph Mercy Oakland
Contact: Site Public Contact
Email: stephanie.couch@stjoeshealth.org

Port Huron
Huron Medical Center PC
Contact: Site Public Contact
Email: research@sncrf.org

Lake Huron Medical Center
Contact: Site Public Contact
Email: research@sncrf.org

McLaren-Port Huron
Contact: Site Public Contact
Email: ctoadmin@karmanos.org

Reed City
Spectrum Health Reed City Hospital
Contact: Site Public Contact
Email: crcwm-regulatory@crcwm.org

Rochester Hills
Great Lakes Cancer Management Specialists-Rochester Hills
Contact: Site Public Contact
Email: stephanie.couch@stjoeshealth.org

Roseville
Michigan Cancer Specialists
Contact: Site Public Contact

Royal Oak
Cancer Care Associates PC
Contact: Site Public Contact

Comprehensive Medical Center PLLC
Contact: Site Public Contact

Hematology Oncology Consultants PC
Contact: Site Public Contact

Oakland Colon Rectal Associates
Contact: Site Public Contact

Oakland Medical Group
Contact: Site Public Contact

William Beaumont Hospital-Royal Oak
Contact: Site Public Contact

Saginaw
Ascension Saint Mary's Hospital
Contact: Site Public Contact
Email: stephanie.couch@stjoeshealth.org

Oncology Hematology Associates of Saginaw Valley PC
Contact: Site Public Contact
Email: stephanie.couch@stjoeshealth.org

Saint Joseph
Lakeland Medical Center Saint Joseph
Contact: Site Public Contact
Email: crcwm-regulatory@crcwm.org

Marie Yeager Cancer Center
Contact: Site Public Contact
Email: crcwm-regulatory@crcwm.org

Shelby Township
Henry Ford Macomb Health Center - Shelby Township
Contact: Site Public Contact
Email: tpearce1@hfhs.org

Southfield
Ascension Providence Hospitals - Southfield
Contact: Site Public Contact
Email: karen.fife@ascension.org

Sterling Heights
Bhadresh Nayak MD PC-Sterling Heights
Contact: Site Public Contact
Email: stephanie.couch@stjoeshealth.org

Mitchell Folbe MD PC
Contact: Site Public Contact

Premier Hematology Oncology Care
Contact: Site Public Contact

Tawas City
Ascension Saint Joseph Hospital
Contact: Site Public Contact
Email: stephanie.couch@stjoeshealth.org

Traverse City
Munson Medical Center
Contact: Site Public Contact
Email: crcwm-regulatory@crcwm.org

Troy
Claudia BR Herke MD PC
Contact: Site Public Contact

GenesisCare USA - Troy
Contact: Site Public Contact
Email: Rudi.Ross@usa.genesiscare.com

Hematology Oncology Consultants PC-Troy
Contact: Site Public Contact

Michigan Institute of Urology-Town Center
Contact: Site Public Contact

William Beaumont Hospital - Troy
Contact: Site Public Contact

Warren
Advanced Breast Care Center PLLC
Contact: Site Public Contact
Email: stephanie.couch@stjoeshealth.org

Great Lakes Cancer Management Specialists-Macomb Professional Building
Contact: Site Public Contact
Email: stephanie.couch@stjoeshealth.org

Macomb Hematology Oncology PC
Contact: Site Public Contact
Email: stephanie.couch@stjoeshealth.org

Michigan Breast Specialists-Warren
Contact: Site Public Contact
Email: stephanie.couch@stjoeshealth.org

Saint John Macomb-Oakland Hospital
Contact: Site Public Contact
Email: stephanie.couch@stjoeshealth.org

West Bloomfield
Henry Ford West Bloomfield Hospital
Contact: Site Public Contact
Email: CTOResearch@hfhs.org

West Branch
Saint Mary's Oncology/Hematology Associates of West Branch
Contact: Site Public Contact
Email: stephanie.couch@stjoeshealth.org

Wyoming
Metro Health Hospital
Contact: Site Public Contact
Email: crcwm-regulatory@crcwm.org

Ypsilanti
Huron Gastroenterology PC
Contact: Site Public Contact
Email: stephanie.couch@stjoeshealth.org

Trinity Health IHA Medical Group Hematology Oncology Ann Arbor Campus
Contact: Site Public Contact
Email: stephanie.couch@stjoeshealth.org

MN
Bemidji
Sanford Joe Lueken Cancer Center
Contact: Site Public Contact
Email: OncologyClinicalTrialsFargo@sanfordhealth.org

Burnsville
Fairview Ridges Hospital
Contact: Site Public Contact
Email: mmcorc@healthpartners.com

Minnesota Oncology - Burnsville
Contact: Site Public Contact
Email: mmcorc@healthpartners.com

Cambridge
Cambridge Medical Center
Contact: Site Public Contact
Email: mmcorc@healthpartners.com

Coon Rapids
Mercy Hospital
Contact: Site Public Contact
Email: mmcorc@healthpartners.com

Edina
Fairview Southdale Hospital
Contact: Site Public Contact
Email: mmcorc@healthpartners.com

Fridley
Unity Hospital
Contact: Site Public Contact
Email: mmcorc@healthpartners.com

Maple Grove
Fairview Clinics and Surgery Center Maple Grove
Contact: Site Public Contact
Email: mmcorc@healthpartners.com

Maplewood
Minnesota Oncology Hematology PA-Maplewood
Contact: Site Public Contact
Email: mmcorc@healthpartners.com

Saint John's Hospital - Healtheast
Contact: Site Public Contact
Email: mmcorc@healthpartners.com

Minneapolis
Abbott-Northwestern Hospital
Contact: Site Public Contact
Email: mmcorc@healthpartners.com

Health Partners Inc
Contact: Site Public Contact
Email: mmcorc@healthpartners.com

Hennepin County Medical Center
Contact: Site Public Contact
Email: mmcorc@healthpartners.com

Monticello
Monticello Cancer Center
Contact: Site Public Contact
Email: mmcorc@healthpartners.com

New Ulm
New Ulm Medical Center
Contact: Site Public Contact
Email: mmcorc@healthpartners.com

Princeton
Fairview Northland Medical Center
Contact: Site Public Contact
Email: mmcorc@healthpartners.com

Robbinsdale
North Memorial Medical Health Center
Contact: Site Public Contact
Email: mmcorc@healthpartners.com

Saint Cloud
Coborn Cancer Center at Saint Cloud Hospital
Contact: Site Public Contact
Email: coborncancercenter@centracare.com

Saint Cloud Hospital
Contact: Site Public Contact

Saint Louis Park
Park Nicollet Clinic - Saint Louis Park
Contact: Site Public Contact
Email: mmcorc@healthpartners.com

Saint Paul
Regions Hospital
Contact: Site Public Contact
Email: mmcorc@healthpartners.com

United Hospital
Contact: Site Public Contact
Email: mmcorc@healthpartners.com

Shakopee
Saint Francis Regional Medical Center
Contact: Site Public Contact
Email: mmcorc@healthpartners.com

Stillwater
Lakeview Hospital
Contact: Site Public Contact
Email: mmcorc@healthpartners.com

Waconia
Ridgeview Medical Center
Contact: Site Public Contact
Email: mmcorc@healthpartners.com

Willmar
Rice Memorial Hospital
Contact: Site Public Contact
Email: mmcorc@healthpartners.com

Woodbury
Minnesota Oncology Hematology PA-Woodbury
Contact: Site Public Contact
Email: mmcorc@healthpartners.com

Wyoming
Fairview Lakes Medical Center
Contact: Site Public Contact
Email: mmcorc@healthpartners.com

MO
Ballwin
Saint Louis Cancer and Breast Institute-Ballwin
Contact: Site Public Contact

Bolivar
Central Care Cancer Center - Bolivar
Contact: Site Public Contact
Email: aroland@kccop.org

Bonne Terre
Parkland Health Center-Bonne Terre
Contact: Site Public Contact

Branson
Cox Cancer Center Branson
Contact: Site Public Contact

Cape Girardeau
Saint Francis Medical Center
Contact: Site Public Contact
Email: sfmc@sfmc.net

Southeast Cancer Center
Contact: Site Public Contact

Chesterfield
Saint Luke's Hospital
Contact: Site Public Contact

Creve Coeur
Siteman Cancer Center at West County Hospital
Contact: Site Public Contact
Email: info@siteman.wustl.edu

Farmington
Parkland Health Center - Farmington
Contact: Site Public Contact

Independence
Centerpoint Medical Center LLC
Contact: Site Public Contact
Email: aroland@kccop.org

Jefferson City
Capital Region Southwest Campus
Contact: Site Public Contact
Email: swooden@mail.crmc.org

Joplin
Freeman Health System
Contact: Site Public Contact
Email: LJCrockett@freemanhealth.com

Mercy Hospital Joplin
Contact: Site Public Contact
Email: esmeralda.carrillo@mercy.net

Kansas City
Research Medical Center
Contact: Site Public Contact
Email: aroland@kccop.org

Saint Luke's Hospital of Kansas City
Contact: Site Public Contact
Email: aroland@kccop.org

Lee's Summit
Saint Luke's East - Lee's Summit
Contact: Site Public Contact
Email: aroland@kccop.org

Rolla
Delbert Day Cancer Institute at PCRMC
Contact: Site Public Contact
Email: kaysmith@phelpshealth.org

Mercy Clinic-Rolla-Cancer and Hematology
Contact: Site Public Contact

Saint Joseph
Heartland Regional Medical Center
Contact: Site Public Contact
Email: linda.schumacher@mymlc.com

Saint Louis
Mercy Hospital Saint Louis
Contact: Site Public Contact

Mercy Hospital South
Contact: Site Public Contact
Email: janet.lesko@mercy.net

Missouri Baptist Medical Center
Contact: Site Public Contact

Saint Louis Cancer and Breast Institute-South City
Contact: Site Public Contact

Siteman Cancer Center at Christian Hospital
Contact: Site Public Contact
Email: info@siteman.wustl.edu

Siteman Cancer Center-South County
Contact: Site Public Contact
Email: info@siteman.wustl.edu

Washington University School of Medicine
Contact: Site Public Contact
Email: info@siteman.wustl.edu

Saint Peters
Siteman Cancer Center at Saint Peters Hospital
Contact: Site Public Contact
Email: info@siteman.wustl.edu

Sainte Genevieve
Sainte Genevieve County Memorial Hospital
Contact: Site Public Contact

Springfield
CoxHealth South Hospital
Contact: Site Public Contact

Mercy Hospital Springfield
Contact: Site Public Contact

Sullivan
Missouri Baptist Sullivan Hospital
Contact: Site Public Contact

Sunset Hills
Missouri Baptist Outpatient Center-Sunset Hills
Contact: Site Public Contact

MS
Grenada
Baptist Cancer Center-Grenada
Contact: Site Public Contact
Email: BCCclintrials@bmhcc.org

New Albany
Baptist Memorial Hospital and Cancer Center-Union County
Contact: Site Public Contact
Email: BCCclintrials@bmhcc.org

Oxford
Baptist Memorial Hospital and Cancer Center-Oxford
Contact: Site Public Contact
Email: BCCclintrials@bmhcc.org

Pascagoula
Singing River Hospital
Contact: Site Public Contact

Southhaven
Baptist Memorial Hospital and Cancer Center-Desoto
Contact: Site Public Contact
Email: BCCclintrials@bmhcc.org

MT
Anaconda
Community Hospital of Anaconda
Contact: Site Public Contact
Email: mccinfo@mtcancer.org

Billings
Billings Clinic Cancer Center
Contact: Site Public Contact
Email: research@billingsclinic.org

Saint Vincent Frontier Cancer Center
Contact: Site Public Contact

Saint Vincent Healthcare
Contact: Site Public Contact
Email: mccinfo@mtcancer.org

Bozeman
Bozeman Deaconess Hospital
Contact: Site Public Contact
Email: mccinfo@mtcancer.org

Butte
Saint James Community Hospital and Cancer Treatment Center
Contact: Site Public Contact

Great Falls
Benefis Healthcare- Sletten Cancer Institute
Contact: Site Public Contact
Email: mccinfo@mtcancer.org

Great Falls Clinic
Contact: Site Public Contact
Email: mccinfo@mtcancer.org

Helena
Saint Peter's Community Hospital
Contact: Site Public Contact
Email: mccinfo@mtcancer.org

Kalispell
Kalispell Regional Medical Center
Contact: Site Public Contact
Email: mccinfo@mtcancer.org

Missoula
Community Medical Hospital
Contact: Site Public Contact
Email: mccinfo@mtcancer.org

Saint Patrick Hospital - Community Hospital
Contact: Site Public Contact
Email: amy.hanneman@providence.org

NC
Asheboro
Randolph Hospital
Contact: Site Public Contact
Email: vivian.sheidler@conehealth.com

Burlington
Cone Health Cancer Center at Alamance Regional
Contact: Site Public Contact
Email: kaye.shoffner@conehealth.com

Clinton
Southeastern Medical Oncology Center-Clinton
Contact: Site Public Contact
Email: jfields@cancersmoc.com

Goldsboro
Southeastern Medical Oncology Center-Goldsboro
Contact: Site Public Contact
Email: jfields@cancersmoc.com

Wayne Memorial Hospital
Contact: Site Public Contact
Email: ecooke@cancersmoc.com

Greensboro
Cone Health Cancer Center
Contact: Site Public Contact
Email: vivian.sheidler@conehealth.com

Hendersonville
Hendersonville Hematology and Oncology at Pardee
Contact: James Earl Radford

Margaret R Pardee Memorial Hospital
Contact: Site Public Contact
Email: karen.morris@unchealth.unc.edu

Jacksonville
Onslow Memorial Hospital
Contact: Site Public Contact
Email: ecooke@cancersmoc.com

Southeastern Medical Oncology Center-Jacksonville
Contact: Site Public Contact
Email: jfields@cancersmoc.com

Kenansville
Vidant Oncology-Kenansville
Contact: Site Public Contact
Email: Carla.Zimmerman@vidanthealth.com

Kinston
Vidant Oncology-Kinston
Contact: Site Public Contact
Email: Carla.Zimmerman@vidanthealth.com

Mebane
Cone Heath Cancer Center at Mebane
Contact: Site Public Contact
Email: kaye.shoffner@conehealth.com

Reidsville
Annie Penn Memorial Hospital
Contact: Site Public Contact
Email: vivian.sheidler@conehealth.com

Richlands
Vidant Oncology-Richlands
Contact: Site Public Contact
Email: Carla.Zimmerman@vidanthealth.com

ND
Bismarck
Sanford Bismarck Medical Center
Contact: Site Public Contact
Email: OncologyClinicalTrialsFargo@sanfordhealth.org

Fargo
Sanford Broadway Medical Center
Contact: Site Public Contact
Email: OncologyClinicalTrialsFargo@sanfordhealth.org

Sanford Clinic North-Fargo
Contact: Preston D. Steen

Sanford Roger Maris Cancer Center
Contact: Site Public Contact
Email: OncologyClinicalTrialsFargo@sanfordhealth.org

Grand Forks
Altru Cancer Center
Contact: Site Public Contact

NE
Bellevue
Nebraska Medicine-Bellevue
Contact: Site Public Contact
Email: unmcrsa@unmc.edu

Grand Island
CHI Health Saint Francis
Contact: Site Public Contact
Email: clinicaltrials@sfmc-gi.org

Kearney
CHI Health Good Samaritan
Contact: Site Public Contact
Email: clinicaltrials@sfmc-gi.org

Heartland Hematology and Oncology
Contact: Site Public Contact
Email: clinicaltrials@sfmc-gi.org

Lincoln
Cancer Partners of Nebraska - Pine Lake
Contact: Site Public Contact
Email: bronsonr@leadingcancercare.com

Saint Elizabeth Regional Medical Center
Contact: Site Public Contact
Email: clinicaltrials@sfmc-gi.org

Southeast Nebraska Cancer Center - 68th Street Place
Contact: Site Public Contact
Email: bronsonr@leadingcancercare.com

Omaha
Alegent Health Bergan Mercy Medical Center
Contact: Site Public Contact
Email: clinicaltrials@sfmc-gi.org

Alegent Health Immanuel Medical Center
Contact: Site Public Contact
Email: clinicaltrials@sfmc-gi.org

Alegent Health Lakeside Hospital
Contact: Site Public Contact
Email: clinicaltrials@sfmc-gi.org

Creighton University Medical Center
Contact: Site Public Contact
Email: clinicaltrials@sfmc-gi.org

Hematology and Oncology Consultants PC
Contact: Site Public Contact
Email: clinicaltrials@sfmc-gi.org

Nebraska Medicine-Village Pointe
Contact: Site Public Contact

Nebraska Methodist Hospital
Contact: Site Public Contact

University of Nebraska Medical Center
Contact: Site Public Contact
Email: unmcrsa@unmc.edu

Papillion
Midlands Community Hospital
Contact: Site Public Contact
Email: clinicaltrials@sfmc-gi.org

NH
Lebanon
Dartmouth Hitchcock Medical Center/Dartmouth Cancer Center
Contact: Site Public Contact
Email: cancer.research.nurse@dartmouth.edu

Manchester
Norris Cotton Cancer Center-Manchester
Contact: Site Public Contact

Nashua
Dartmouth Cancer Center - Nashua
Contact: Site Public Contact
Email: Laura.A.Menken@hitchcock.org

NJ
Brick
Ocean University Medical Center
Contact: Site Public Contact

Cape May Court House
AtlantiCare Health Park-Cape May Court House
Contact: Site Public Contact

Egg Harbor Township
AtlantiCare Surgery Center
Contact: Site Public Contact

Flemington
Hunterdon Medical Center
Contact: Site Public Contact

Hackensack
Hackensack University Medical Center
Contact: Site Public Contact

Moorestown
Virtua Samson Cancer Center
Contact: Site Public Contact

Morristown
Morristown Medical Center
Contact: Site Public Contact

Mount Holly
Virtua Memorial
Contact: Site Public Contact

Neptune
Jersey Shore Medical Center
Contact: Site Public Contact

Newton
Newton Medical Center
Contact: Site Public Contact

Paramus
The Valley Hospital-Luckow Pavilion
Contact: Site Public Contact

Pompton
Chilton Medical Center
Contact: Site Public Contact

Ridgewood
Neurosurgeons of New Jersey-Ridgewood
Contact: Site Public Contact
Email: ctsucontact@westat.com

Valley Hospital
Contact: Site Public Contact
Email: cparish@valleyhealth.com

Summit
Overlook Hospital
Contact: Site Public Contact

Teaneck
Holy Name Hospital
Contact: Site Public Contact

Voorhees
Virtua Voorhees
Contact: Site Public Contact

Wayne
Valley Medical Group - Wayne Multispecialty Practice
Contact: Site Public Contact
Email: pkurth@valleyhealth.com

Westwood
Valley Health System-Hematology/Oncology
Contact: Site Public Contact
Email: ctsucontact@westat.com

NM
Albuquerque
Lovelace Medical Center-Downtown
Contact: Site Public Contact
Email: AYost@nmcca.org

Lovelace Medical Center-Saint Joseph Square
Contact: Site Public Contact
Email: AYost@nmcca.org

New Mexico Oncology Hematology Consultants
Contact: Site Public Contact
Email: CLee@nmcca.org

Presbyterian Kaseman Hospital
Contact: Site Public Contact
Email: WBurman@phs.org

University of New Mexico Cancer Center
Contact: Site Public Contact
Email: LByatt@nmcca.org

Las Cruces
Memorial Medical Center - Las Cruces
Contact: Site Public Contact
Email: Kim.Hoffman@lpnt.net

Rio Rancho
Presbyterian Rust Medical Center/Jorgensen Cancer Center
Contact: Site Public Contact
Email: WBurman@phs.org

Santa Fe
Christus Saint Vincent Regional Cancer Center
Contact: Site Public Contact
Email: Olivia.Sloan@nmcancercare.com

NV
Carson City
Carson Tahoe Regional Medical Center
Contact: Site Public Contact
Email: research@sncrf.org

Henderson
Cancer and Blood Specialists-Henderson
Contact: Site Public Contact
Email: research@sncrf.org

Comprehensive Cancer Centers of Nevada - Henderson
Contact: Site Public Contact
Email: research@sncrf.org

Comprehensive Cancer Centers of Nevada-Horizon Ridge
Contact: Site Public Contact
Email: research@sncrf.org

Comprehensive Cancer Centers of Nevada-Southeast Henderson
Contact: Site Public Contact
Email: research@sncrf.org

GenesisCare USA - Henderson
Contact: Site Public Contact
Email: research@sncrf.org

Las Vegas Cancer Center-Henderson
Contact: Site Public Contact
Email: research@sncrf.org

Las Vegas Urology - Green Valley
Contact: Site Public Contact
Email: research@sncrf.org

Las Vegas Urology - Pebble
Contact: Site Public Contact
Email: research@sncrf.org

OptumCare Cancer Care at Seven Hills
Contact: Site Public Contact
Email: research@sncrf.org

Urology Specialists of Nevada - Green Valley
Contact: Site Public Contact
Email: research@sncrf.org

Las Vegas
Alliance for Childhood Diseases/Cure 4 the Kids Foundation
Contact: Site Public Contact
Email: research@sncrf.org

Ann M Wierman MD LTD
Contact: Site Public Contact
Email: research@sncrf.org

Cancer Therapy and Integrative Medicine
Contact: Site Public Contact
Email: research@sncrf.org

Cancer and Blood Specialists-Shadow
Contact: Site Public Contact
Email: research@sncrf.org

Cancer and Blood Specialists-Tenaya
Contact: Site Public Contact
Email: research@sncrf.org

Comprehensive Cancer Centers of Nevada
Contact: Site Public Contact
Email: research@sncrf.org

Comprehensive Cancer Centers of Nevada - Central Valley
Contact: Site Public Contact
Email: research@sncrf.org

Comprehensive Cancer Centers of Nevada - Northwest
Contact: Site Public Contact
Email: research@sncrf.org

Comprehensive Cancer Centers of Nevada - Town Center
Contact: Site Public Contact
Email: research@sncrf.org

Comprehensive Cancer Centers of Nevada-Summerlin
Contact: Site Public Contact
Email: research@sncrf.org

Desert West Surgery
Contact: Site Public Contact
Email: research@sncrf.org

GenesisCare USA - Fort Apache
Contact: Site Public Contact
Email: research@sncrf.org

GenesisCare USA - Las Vegas
Contact: Site Public Contact
Email: research@sncrf.org

GenesisCare USA - Vegas Tenaya
Contact: Site Public Contact
Email: research@sncrf.org

HealthCare Partners Medical Group Oncology/Hematology-Centennial Hills
Contact: Site Public Contact
Email: research@sncrf.org

HealthCare Partners Medical Group Oncology/Hematology-Maryland Parkway
Contact: Site Public Contact
Email: research@sncrf.org

HealthCare Partners Medical Group Oncology/Hematology-San Martin
Contact: Site Public Contact
Email: research@sncrf.org

HealthCare Partners Medical Group Oncology/Hematology-Tenaya
Contact: Site Public Contact
Email: research@sncrf.org

Hope Cancer Care of Nevada
Contact: Site Public Contact
Email: research@sncrf.org

Las Vegas Cancer Center-Medical Center
Contact: Site Public Contact
Email: research@sncrf.org

Las Vegas Prostate Cancer Center
Contact: Site Public Contact
Email: research@sncrf.org

Las Vegas Urology - Cathedral Rock
Contact: Site Public Contact
Email: research@sncrf.org

Las Vegas Urology - Pecos
Contact: Site Public Contact
Email: research@sncrf.org

Las Vegas Urology - Smoke Ranch
Contact: Site Public Contact
Email: research@smcrf.org

Las Vegas Urology - Sunset
Contact: Site Public Contact
Email: research@sncrf.org

OptumCare Cancer Care at Charleston
Contact: Site Public Contact
Email: research@sncrf.org

OptumCare Cancer Care at Fort Apache
Contact: Site Public Contact
Email: research@sncrf.org

OptumCare Cancer Care at MountainView
Contact: Site Public Contact
Email: research@sncrf.org

Radiation Oncology Centers of Nevada Central
Contact: Site Public Contact
Email: research@sncrf.org

Radiation Oncology Centers of Nevada Southeast
Contact: Site Public Contact
Email: research@sncrf.org

Summerlin Hospital Medical Center
Contact: Site Public Contact
Email: research@sncrf.org

Sunrise Hospital and Medical Center
Contact: Site Public Contact
Email: research@sncrf.org

University Cancer Center
Contact: Site Public Contact
Email: research@sncrf.org

University Medical Center of Southern Nevada
Contact: Site Public Contact
Email: research@sncrf.org

Urology Specialists of Nevada - Central
Contact: Site Public Contact
Email: research@sncrf.org

Urology Specialists of Nevada - Northwest
Contact: Site Public Contact
Email: research@sncrf.org

Urology Specialists of Nevada - Southwest
Contact: Site Public Contact
Email: research@sncrf.org

Pahrump
Hope Cancer Care of Nevada-Pahrump
Contact: Site Public Contact
Email: research@sncrf.org

Reno
Radiation Oncology Associates
Contact: Site Public Contact
Email: research@sncrf.org

Renown Regional Medical Center
Contact: Site Public Contact
Email: research@sncrf.org

Saint Mary's Regional Medical Center
Contact: Site Public Contact
Email: research@sncrf.org

NY
Auburn
Hematology Oncology Associates of Central New York-Auburn
Contact: Site Public Contact

Bay Shore
Northwell Health Imbert Cancer Center
Contact: Site Public Contact

Bronx
Montefiore Medical Center - Moses Campus
Contact: Site Public Contact
Email: eskwak@montefiore.org

Montefiore Medical Center-Einstein Campus
Contact: Site Public Contact
Email: eskwak@montefiore.org

Montefiore Medical Center-Weiler Hospital
Contact: Site Public Contact
Email: eskwak@montefiore.org

Buffalo
Roswell Park Cancer Institute
Contact: Site Public Contact
Email: askroswell@roswellpark.org

East Syracuse
Hematology Oncology Associates of Central New York-East Syracuse
Contact: Site Public Contact

Lake Success
Northwell Health/Center for Advanced Medicine
Contact: Site Public Contact

New York
NYP/Weill Cornell Medical Center
Contact: Site Public Contact

Rochester
Highland Hospital
Contact: Site Public Contact

University of Rochester
Contact: Site Public Contact

Staten Island
Staten Island University Hospital
Contact: Site Public Contact

Stony Brook
Stony Brook University Medical Center
Contact: Site Public Contact

Syracuse
Hematology Oncology Associates of Central New York-Onondaga Hill
Contact: Site Public Contact

SUNY Upstate Medical Center-Community Campus
Contact: Site Public Contact
Email: ctsucontact@westat.com

State University of New York Upstate Medical University
Contact: Site Public Contact

White Plains
Dickstein Cancer Treatment Center
Contact: Site Public Contact
Email: mcortese@wphospital.org

OH
Akron
Cleveland Clinic Akron General
Contact: Site Public Contact
Email: CancerAnswer@ccf.org

Summa Health System - Akron Campus
Contact: Site Public Contact
Email: cancerresearch@summahealth.org

Beachwood
UHHS-Chagrin Highlands Medical Center
Contact: Site Public Contact
Email: CTUReferral@UHhospitals.org

Beavercreek
Indu and Raj Soin Medical Center
Contact: Site Public Contact
Email: clinical.trials@daytonncorp.org

Belpre
Strecker Cancer Center-Belpre
Contact: Site Public Contact
Email: sheree@columbusccop.org

Boardman
Saint Elizabeth Boardman Hospital
Contact: Site Public Contact
Email: clinical.trials@daytonncorp.org

Centerville
Dayton Physicians LLC-Miami Valley South
Contact: Site Public Contact
Email: clinical.trials@daytonncorp.org

Miami Valley Hospital South
Contact: Site Public Contact
Email: clinical.trials@daytonncorp.org

Chardon
Geauga Hospital
Contact: Site Public Contact
Email: CTUReferral@UHhospitals.org

Chillicothe
Adena Regional Medical Center
Contact: Site Public Contact
Email: sheree@columbusccop.org

Cincinnati
Bethesda North Hospital
Contact: Site Public Contact
Email: clinicaltrials@sfmc-gi.org

Good Samaritan Hospital - Cincinnati
Contact: Site Public Contact
Email: clinicaltrials@sfmc-gi.org

Oncology Hematology Care Inc-Anderson
Contact: Site Public Contact
Email: clinical.trials@daytonncorp.org

Oncology Hematology Care Inc-Blue Ash
Contact: Site Public Contact
Email: clinical.trials@daytonncorp.org

Oncology Hematology Care Inc-Eden Park
Contact: Site Public Contact
Email: clinical.trials@daytonncorp.org

Oncology Hematology Care Inc-Kenwood
Contact: Site Public Contact
Email: clinical.trials@daytonncorp.org

Oncology Hematology Care Inc-Mercy West
Contact: Site Public Contact
Email: clinical.trials@daytonncorp.org

TriHealth Cancer Institute-Anderson
Contact: Site Public Contact
Email: clinicaltrials@sfmc-gi.org

TriHealth Cancer Institute-Westside
Contact: Site Public Contact
Email: clinicaltrials@sfmc-gi.org

University of Cincinnati Cancer Center-UC Medical Center
Contact: Site Public Contact
Email: uchealthnews@uc.edu

Cleveland
Case Western Reserve University
Contact: Site Public Contact
Email: CTUReferral@UHhospitals.org

Columbus
Columbus Oncology and Hematology Associates Inc
Contact: Site Public Contact
Email: sheree@columbusccop.org

Doctors Hospital
Contact: Site Public Contact
Email: sheree@columbusccop.org

Grant Medical Center
Contact: Site Public Contact
Email: sheree@columbusccop.org

Mount Carmel East Hospital
Contact: Site Public Contact
Email: sheree@columbusccop.org

Mount Carmel Health Center West
Contact: Site Public Contact
Email: sheree@columbusccop.org

Ohio State University Comprehensive Cancer Center
Contact: Site Public Contact
Email: Jamesline@osumc.edu

Riverside Methodist Hospital
Contact: Site Public Contact
Email: sheree@columbusccop.org

The Mark H Zangmeister Center
Contact: Site Public Contact
Email: sheree@columbusccop.org

Dayton
Dayton Physician LLC-Miami Valley Hospital North
Contact: Site Public Contact
Email: clinical.trials@daytonncorp.org

Good Samaritan Hospital - Dayton
Contact: Site Public Contact
Email: clinical.trials@daytonncorp.org

Miami Valley Hospital
Contact: Site Public Contact
Email: clinical.trials@daytonncorp.org

Miami Valley Hospital North
Contact: Site Public Contact
Email: clinical.trials@daytonncorp.org

Delaware
Delaware Health Center-Grady Cancer Center
Contact: Site Public Contact
Email: sheree@columbusccop.org

Delaware Radiation Oncology
Contact: Site Public Contact
Email: sheree@columbusccop.org

Grady Memorial Hospital
Contact: Site Public Contact
Email: sheree@columbusccop.org

Dublin
Dublin Methodist Hospital
Contact: Site Public Contact
Email: sheree@columbusccop.org

Elyria
Mercy Cancer Center-Elyria
Contact: Site Public Contact
Email: CTUReferral@UHhospitals.org

Fairfield
Oncology Hematology Care Inc-Healthplex
Contact: Site Public Contact
Email: clinical.trials@daytonncorp.org

Findlay
Armes Family Cancer Center
Contact: Site Public Contact
Email: clinical.trials@daytonncorp.org

Blanchard Valley Hospital
Contact: Site Public Contact
Email: clinical.trials@daytonncorp.org

Orion Cancer Care
Contact: Site Public Contact
Email: clinical.trials@daytonncorp.org

Franklin
Atrium Medical Center-Middletown Regional Hospital
Contact: Site Public Contact
Email: clinical.trials@daytonncorp.org

Dayton Physicians LLC-Atrium
Contact: Site Public Contact
Email: clinical.trials@daytonncorp.org

Greenville
Dayton Physicians LLC-Wayne
Contact: Site Public Contact
Email: clinical.trials@daytonncorp.org

Wayne Hospital
Contact: Site Public Contact
Email: clinical.trials@daytonncorp.org

Grove City
Mount Carmel Grove City Hospital
Contact: Site Public Contact
Email: sheree@columbusccop.org

Kettering
First Dayton Cancer Care
Contact: Site Public Contact
Email: clinical.trials@daytonncorp.org

Greater Dayton Cancer Center
Contact: Site Public Contact
Email: clinical.trials@daytonncorp.org

Kettering Medical Center
Contact: Site Public Contact
Email: clinical.trials@daytonncorp.org

Lancaster
Fairfield Medical Center
Contact: Site Public Contact
Email: sheree@columbusccop.org

Lima
Saint Rita's Medical Center
Contact: Site Public Contact

Mansfield
OhioHealth Mansfield Hospital
Contact: Site Public Contact
Email: sheree@columbusccop.org

Marietta
Marietta Memorial Hospital
Contact: Site Public Contact
Email: sheree@columbusccop.org

Marion
OhioHealth Marion General Hospital
Contact: Site Public Contact
Email: sheree@columbusccop.org

Maumee
Toledo Clinic Cancer Centers-Maumee
Contact: Site Public Contact

Toledo Radiation Oncology at Northwest Ohio Onocolgy Center
Contact: Site Public Contact

Mayfield Heights
UH Seidman Cancer Center at Landerbrook Health Center
Contact: Site Public Contact
Email: CTUReferral@UHhospitals.org

Mentor
UH Seidman Cancer Center at Lake Health Mentor Campus
Contact: Site Public Contact
Email: CTUReferral@UHhospitals.org

Middleburg Heights
UH Seidman Cancer Center at Southwest General Hospital
Contact: Site Public Contact
Email: CTUReferral@UHhospitals.org

Middletown
Dayton Physicians LLC-Signal Point
Contact: Site Public Contact
Email: clinical.trials@daytonncorp.org

Mount Vernon
Knox Community Hospital
Contact: Site Public Contact
Email: sheree@columbusccop.org

Newark
Licking Memorial Hospital
Contact: Site Public Contact
Email: sheree@columbusccop.org

Newark Radiation Oncology
Contact: Site Public Contact
Email: sheree@columbusccop.org

Oregon
Saint Charles Hospital
Contact: Site Public Contact

Parma
University Hospitals Parma Medical Center
Contact: Site Public Contact
Email: CTUReferral@UHhospitals.org

Perrysburg
Mercy Health Perrysburg Cancer Center
Contact: Site Public Contact
Email: sheree@columbusccop.org

Portsmouth
Southern Ohio Medical Center
Contact: Site Public Contact
Email: sheree@columbusccop.org

Sandusky
UH Seidman Cancer Center at Firelands Regional Medical Center
Contact: Site Public Contact
Email: CTUReferral@UHhospitals.org

Sidney
Dayton Physicians LLC-Wilson
Contact: Site Public Contact
Email: clinical.trials@daytonncorp.org

Springfield
Springfield Regional Cancer Center
Contact: Site Public Contact
Email: clinical.trials@daytonncorp.org

Springfield Regional Medical Center
Contact: Site Public Contact
Email: clinical.trials@daytonncorp.org

Steubenville
Trinity's Tony Teramana Cancer Center
Contact: Site Public Contact

Sylvania
ProMedica Flower Hospital
Contact: Site Public Contact

Toledo
Mercy Health - Saint Anne Hospital
Contact: Site Public Contact
Email: sheree@columbusccop.org

ProMedica Toledo Hospital/Russell J Ebeid Children's Hospital
Contact: Site Public Contact

Toledo Clinic Cancer Centers-Toledo
Contact: Site Public Contact

Troy
Dayton Physicians LLC - Troy
Contact: Site Public Contact
Email: clinical.trials@daytonncorp.org

Upper Valley Medical Center
Contact: Site Public Contact
Email: clinical.trials@daytonncorp.org

Wadsworth
University Hospitals Sharon Health Center
Contact: Site Public Contact
Email: CTUReferral@UHhospitals.org

Warren
Saint Joseph Warren Hospital
Contact: Site Public Contact
Email: clinical.trials@daytonncorp.org

West Chester
University of Cincinnati Cancer Center-West Chester
Contact: Site Public Contact
Email: clinicaltrials@ucphysicians.com

Westerville
Saint Ann's Hospital
Contact: Site Public Contact
Email: sheree@columbusccop.org

Westlake
UH Seidman Cancer Center at Saint John Medical Center
Contact: Site Public Contact
Email: CTUReferral@UHhospitals.org

UHHS-Westlake Medical Center
Contact: Site Public Contact
Email: CTUReferral@UHhospitals.org

Youngstown
Saint Elizabeth Youngstown Hospital
Contact: Site Public Contact
Email: clinical.trials@daytonncorp.org

Zanesville
Genesis Healthcare System Cancer Care Center
Contact: Site Public Contact
Email: sheree@columbusccop.org

OK
Lawton
Cancer Centers of Southwest Oklahoma Research
Contact: Site Public Contact

Oklahoma City
Mercy Hospital Oklahoma City
Contact: Site Public Contact

University of Oklahoma Health Sciences Center
Contact: Site Public Contact
Email: ou-clinical-trials@ouhsc.edu

Tulsa
Oklahoma Cancer Specialists and Research Institute-Tulsa
Contact: Site Public Contact

OR
Baker City
Saint Alphonsus Medical Center-Baker City
Contact: Site Public Contact
Email: stephanie.couch@stjoeshealth.org

Bend
Saint Charles Health System
Contact: Site Public Contact
Email: nosall@stcharleshealthcare.org

Clackamas
Clackamas Radiation Oncology Center
Contact: Site Public Contact
Email: CanRsrchStudies@providence.org

Providence Cancer Institute Clackamas Clinic
Contact: Site Public Contact
Email: CanRsrchStudies@providence.org

Coos Bay
Bay Area Hospital
Contact: Site Public Contact
Email: cherie.cox@bayareahospital.org

Corvallis
Good Samaritan Hospital
Contact: Site Public Contact
Email: stmock@samhealth.org

Newberg
Providence Newberg Medical Center
Contact: Site Public Contact
Email: CanRsrchStudies@providence.org

Ontario
Saint Alphonsus Medical Center-Ontario
Contact: Site Public Contact
Email: stephanie.couch@stjoeshealth.org

Oregon City
Providence Willamette Falls Medical Center
Contact: Site Public Contact
Email: CanRsrchStudies@providence.org

Portland
Providence Portland Medical Center
Contact: Site Public Contact
Email: CanRsrchStudies@providence.org

Providence Saint Vincent Medical Center
Contact: Site Public Contact
Email: CanRsrchStudies@providence.org

Redmond
Saint Charles Health System-Redmond
Contact: Site Public Contact

PA
Abington
Jefferson Abington Hospital
Contact: Site Public Contact

Allentown
Lehigh Valley Hospital-Cedar Crest
Contact: Site Public Contact
Email: stephanie.couch@stjoeshealth.org

Beaver
UPMC-Heritage Valley Health System Beaver
Contact: Site Public Contact

Bethlehem
Lehigh Valley Hospital - Muhlenberg
Contact: Site Public Contact
Email: stephanie.couch@stjoeshealth.org

Saint Luke's University Hospital-Bethlehem Campus
Contact: Site Public Contact

Bryn Mawr
Bryn Mawr Hospital
Contact: Site Public Contact
Email: turzoe@mlhs.org

Chadds Ford
Christiana Care Health System-Concord Health Center
Contact: Site Public Contact
Email: mhayden@christianacare.org

Collegeville
Main Line Health Center-Collegeville
Contact: Site Public Contact
Email: turzoe@mlhs.org

Danville
Geisinger Medical Center
Contact: Site Public Contact
Email: HemonCCTrials@geisinger.edu

East Norriton
Fox Chase Cancer Center - East Norriton Hospital Outpatient Center
Contact: Site Public Contact
Email: ecog.rss@jimmy.harvard.edu

East Stroudsburg
Pocono Medical Center
Contact: Site Public Contact
Email: stephanie.couch@stjoeshealth.org

Erie
UPMC Hamot
Contact: Site Public Contact

UPMC Hillman Cancer Center Erie
Contact: Site Public Contact
Email: haneydl@upmc.edu

Exton
Main Line Health Center-Exton
Contact: Site Public Contact
Email: turzoe@mlhs.org

Greensburg
UPMC Cancer Centers - Arnold Palmer Pavilion
Contact: Site Public Contact

Harrisburg
UPMC Pinnacle Cancer Center/Community Osteopathic Campus
Contact: Site Public Contact
Email: klitchfield@PINNACLEHEALTH.org

UPMC Pinnacle Harrisburg
Contact: Site Public Contact
Email: ecog.rss@jimmy.harvard.edu

Hazleton
Geisinger Medical Center-Cancer Center Hazleton
Contact: Site Public Contact
Email: HemonCCTrials@geisinger.edu

Lehigh Valley Hospital-Hazleton
Contact: Site Public Contact
Email: stephanie.couch@stjoeshealth.org

Hershey
Penn State Milton S Hershey Medical Center
Contact: Site Public Contact
Email: CTO@hmc.psu.edu

Johnstown
UPMC-Johnstown/John P. Murtha Regional Cancer Center
Contact: Site Public Contact

Langhorne
Saint Mary Medical and Regional Cancer Center
Contact: Site Public Contact

Lewisburg
Geisinger Medical Oncology-Lewisburg
Contact: Site Public Contact
Email: HemonCCTrials@geisinger.edu

Lewistown
Lewistown Hospital
Contact: Site Public Contact
Email: HemonCCTrials@geisinger.edu

McKeesport
UPMC Cancer Center at UPMC McKeesport
Contact: Site Public Contact

Meadowbrook
Holy Redeemer Hospital and Medical Center
Contact: Site Public Contact

Media
Riddle Memorial Hospital
Contact: Site Public Contact
Email: turzoe@mlhs.org

Moon Township
UPMC Hillman Cancer Center in Coraopolis
Contact: Site Public Contact

Paoli
Paoli Memorial Hospital
Contact: Site Public Contact
Email: turzoe@mlhs.org

Philadelphia
Fox Chase Cancer Center
Contact: Site Public Contact

University of Pennsylvania/Abramson Cancer Center
Contact: Site Public Contact

Pittsburgh
UPMC Jefferson Regional Radiation Oncology
Contact: Site Public Contact

UPMC-Magee Womens Hospital
Contact: Site Public Contact

UPMC-Passavant Hospital
Contact: Site Public Contact

UPMC-Presbyterian Hospital
Contact: Site Public Contact

UPMC-Saint Clair Hospital Cancer Center
Contact: Site Public Contact

UPMC-Saint Margaret
Contact: Site Public Contact

UPMC-Shadyside Hospital
Contact: Site Public Contact

University of Pittsburgh Cancer Institute (UPCI)
Contact: Site Public Contact

Pottsville
Geisinger Cancer Services-Pottsville
Contact: Site Public Contact
Email: HemonCCTrials@geisinger.edu

Sayre
Guthrie Medical Group PC-Robert Packer Hospital
Contact: Site Public Contact

Scranton
Community Medical Center
Contact: Site Public Contact
Email: HemonCCTrials@geisinger.edu

Selinsgrove
Geisinger Medical Oncology-Selinsgrove
Contact: Site Public Contact
Email: HemonCCTrials@geisinger.edu

Seneca
UPMC Cancer Center at UPMC Northwest
Contact: Site Public Contact

State College
Geisinger Medical Group
Contact: Site Public Contact
Email: HemonCCTrials@geisinger.edu

Uniontown
UPMC Uniontown Hospital Radiation Oncology
Contact: Site Public Contact

Washington
UPMC Washington Hospital Radiation Oncology
Contact: Site Public Contact
Email: cancer@washingtonhospital.org

West Chester
Chester County Hospital
Contact: Site Public Contact

Wilkes-Barre
Geisinger Wyoming Valley/Henry Cancer Center
Contact: Site Public Contact
Email: HemonCCTrials@geisinger.edu

Williamsport
UPMC Susquehanna
Contact: Site Public Contact

Willow Grove
Asplundh Cancer Pavilion
Contact: Site Public Contact

Wynnewood
Lankenau Medical Center
Contact: Site Public Contact
Email: turzoe@mlhs.org

SC
Beaufort
Beaufort Memorial Hospital
Contact: Site Public Contact
Email: kwade@bmhsc.org

Boiling Springs
Prisma Health Cancer Institute - Spartanburg
Contact: Site Public Contact
Email: kim.williams3@prismahealth.org

Charleston
Medical University of South Carolina
Contact: Site Public Contact
Email: hcc-clinical-trials@musc.edu

Easley
Prisma Health Cancer Institute - Easley
Contact: Site Public Contact
Email: kim.williams3@prismahealth.org

Gaffney
Gibbs Cancer Center-Gaffney
Contact: Site Public Contact
Email: kmertz-rivera@gibbscc.org

Georgetown
Tidelands Georgetown Memorial Hospital
Contact: Site Public Contact
Email: broe@tidelandshealth.org

Greenville
Greenville Health System Cancer Institute-Andrews
Contact: Site Public Contact
Email: kwilliams8@ghs.org

Prisma Health Cancer Institute - Butternut
Contact: Site Public Contact
Email: kim.williams3@prismahealth.org

Prisma Health Cancer Institute - Eastside
Contact: Site Public Contact
Email: kim.williams3@prismahealth.org

Prisma Health Cancer Institute - Faris
Contact: Site Public Contact
Email: kim.williams3@prismahealth.org

Saint Francis Cancer Center
Contact: Site Public Contact
Email: melissa_beckman@bshsi.org

Saint Francis Hospital
Contact: Site Public Contact
Email: melissa_beckman@bshsi.org

Greenwood
Self Regional Healthcare
Contact: Site Public Contact
Email: nmcgaha@selfregional.org

Greer
Gibbs Cancer Center-Pelham
Contact: Site Public Contact
Email: kmertz-rivera@gibbscc.org

Prisma Health Cancer Institute - Greer
Contact: Site Public Contact
Email: kim.williams3@prismahealth.org

Seneca
Prisma Health Cancer Institute - Seneca
Contact: Site Public Contact
Email: kim.williams3@prismahealth.org

Spartanburg
Spartanburg Medical Center
Contact: Site Public Contact
Email: kmertz-rivera@gibbscc.org

Union
MGC Hematology Oncology-Union
Contact: Site Public Contact
Email: kmertz-rivera@gibbscc.org

West Columbia
Lexington Medical Center
Contact: Site Public Contact
Email: LMCIRB@lexhealth.org

SD
Rapid City
Rapid City Regional Hospital
Contact: Site Public Contact
Email: research@rcrh.org

Sioux Falls
Sanford Cancer Center Oncology Clinic
Contact: Site Public Contact
Email: OncologyClinicTrialsSF@sanfordhealth.org

Sanford USD Medical Center - Sioux Falls
Contact: Site Public Contact
Email: OncologyClinicalTrialsSF@SanfordHealth.org

TN
Chattanooga
Memorial Hospital
Contact: Site Public Contact
Email: clinicaltrials@sfmc-gi.org

Collierville
Baptist Memorial Hospital and Cancer Center-Collierville
Contact: Site Public Contact
Email: BCCclintrials@bmhcc.org

Integrity Oncology PLLC-Collierville
Contact: Site Public Contact
Email: ctsucontact@westat.com

Franklin
Vanderbilt-Ingram Cancer Center Cool Springs
Contact: Site Public Contact

Hixson
Pulmonary Medicine Center of Chattanooga-Hixson
Contact: Site Public Contact
Email: clinicaltrials@sfmc-gi.org

Memphis
Baptist Memorial Hospital and Cancer Center-Memphis
Contact: Site Public Contact
Email: BCCclintrials@bmhcc.org

Baptist Memorial Hospital for Women
Contact: Site Public Contact
Email: BCCclintrials@bmhcc.org

Family Cancer Center-Memphis
Contact: Site Public Contact
Email: ecog.rss@jimmy.harvard.edu

Nashville
Meharry Medical College
Contact: Site Public Contact
Email: Nancy.McCullough@NashvilleHA.org

Vanderbilt Breast Center at One Hundred Oaks
Contact: Site Public Contact

Vanderbilt University/Ingram Cancer Center
Contact: Site Public Contact

Ooltewah
Memorial GYN Plus
Contact: Site Public Contact
Email: clinicaltrials@sfmc-gi.org

TX
Amarillo
The Don and Sybil Harrington Cancer Center
Contact: Site Public Contact
Email: Gina.Cravey@bsahs.org

Austin
Dell Seton Medical Center at The University of Texas
Contact: Site Public Contact

Bryan
Saint Joseph Regional Cancer Center
Contact: Site Public Contact
Email: clinicaltrials@sfmc-gi.org

Dallas
Parkland Memorial Hospital
Contact: Site Public Contact
Email: canceranswerline@UTSouthwestern.edu

UT Southwestern/Simmons Cancer Center-Dallas
Contact: Site Public Contact
Email: canceranswerline@UTSouthwestern.edu

Fort Worth
UT Southwestern/Simmons Cancer Center-Fort Worth
Contact: Site Public Contact
Email: canceranswerline@UTSouthwestern.edu

Laredo
Doctor's Hospital of Laredo
Contact: Site Public Contact

Richardson
UT Southwestern Clinical Center at Richardson/Plano
Contact: Site Public Contact
Email: Suzanne.cole@utsouthwestern.edu

UT
American Fork
American Fork Hospital / Huntsman Intermountain Cancer Center
Contact: Site Public Contact
Email: officeofresearch@imail.org

Cedar City
Sandra L Maxwell Cancer Center
Contact: Site Public Contact
Email: officeofresearch@imail.org

Farmington
Farmington Health Center
Contact: Site Public Contact
Email: cancerinfo@hci.utah.edu

Logan
Logan Regional Hospital
Contact: Site Public Contact
Email: officeofresearch@imail.org

Murray
Intermountain Medical Center
Contact: Site Public Contact
Email: officeofresearch@imail.org

Ogden
McKay-Dee Hospital Center
Contact: Site Public Contact
Email: officeofresearch@imail.org

Provo
Utah Valley Regional Medical Center
Contact: Site Public Contact
Email: officeofresearch@imail.org

Riverton
Riverton Hospital
Contact: Site Public Contact
Email: officeofresearch@imail.org

Saint George
Saint George Regional Medical Center
Contact: Site Public Contact
Email: officeofresearch@imail.org

Salt Lake City
Huntsman Cancer Institute/University of Utah
Contact: Site Public Contact
Email: cancerinfo@hci.utah.edu

LDS Hospital
Contact: Site Public Contact
Email: officeofresearch@imail.org

University of Utah Sugarhouse Health Center
Contact: Site Public Contact
Email: cancerinfo@hci.utah.edu

Utah Cancer Specialists-Salt Lake City
Contact: Site Public Contact
Email: officeofresearch@imail.org

South Jordan
South Jordan Health Center
Contact: Site Public Contact
Email: cancerinfo@hci.utah.edu

VA
Lynchburg
Centra Lynchburg Hematology-Oncology Clinic Inc
Contact: Site Public Contact
Email: Kevin.Patel@centrahealth.com

Martinsville
Sovah Health Martinsville
Contact: Site Public Contact
Email: sharon.hubbard@lpnt.net

Richmond
VCU Massey Cancer Center at Stony Point
Contact: Site Public Contact
Email: mwellons@vcu.edu

Virginia Commonwealth University/Massey Cancer Center
Contact: Site Public Contact
Email: klcampbell@vcu.edu

South Hill
VCU Community Memorial Health Center
Contact: Site Public Contact
Email: sherman.baker@vcuhealth.org

Winchester
Shenandoah Oncology PC
Contact: Site Public Contact
Email: William.Houck@usoncology.com

VT
Saint Johnsbury
Norris Cotton Cancer Center-North
Contact: Site Public Contact

WI
Antigo
Langlade Hospital and Cancer Center
Contact: Site Public Contact
Email: Juli.Alford@aspirus.org

Appleton
ThedaCare Regional Cancer Center
Contact: Site Public Contact
Email: ResearchDept@thedacare.org

Chippewa Falls
Marshfield Clinic-Chippewa Center
Contact: Site Public Contact
Email: oncology.clinical.trials@marshfieldresearch.org

Eau Claire
HSHS Sacred Heart Hospital
Contact: Site Public Contact
Email: ewd_research_admin@hshs.org

Marshfield Clinic Cancer Center at Sacred Heart
Contact: Site Public Contact
Email: oncology.clinical.trials@marshfieldresearch.org

Marshfield Medical Center-EC Cancer Center
Contact: Site Public Contact
Email: oncology.clinical.trials@marshfieldresearch.org

Green Bay
Green Bay Oncology Limited at Saint Mary's Hospital
Contact: Brian Leslie Burnette

Green Bay Oncology at Saint Vincent Hospital
Contact: Brian Leslie Burnette

Saint Vincent Hospital Cancer Center Green Bay
Contact: Site Public Contact
Email: ewd_research_admin@hshs.org

Saint Vincent Hospital Cancer Center at Saint Mary's
Contact: Site Public Contact
Email: ewd_research_admin@hshs.org

Johnson Creek
UW Cancer Center Johnson Creek
Contact: Site Public Contact
Email: lynda.persico@uwmf.wisc.edu

La Crosse
Gundersen Lutheran Medical Center
Contact: Site Public Contact
Email: cancerctr@gundersenhealth.org

Ladysmith
Marshfield Clinic - Ladysmith Center
Contact: Site Public Contact
Email: oncology.clinical.trials@marshfieldresearch.org

Madison
Dean Hematology and Oncology Clinic
Contact: Site Public Contact

University of Wisconsin Carbone Cancer Center
Contact: Site Public Contact

Manitowoc
Holy Family Memorial Hospital
Contact: Site Public Contact

Marinette
Saint Vincent Hospital Cancer Center at Marinette
Contact: Site Public Contact
Email: Christy.Gilchrist@hshs.org

Marshfield
Marshfield Medical Center-Marshfield
Contact: Site Public Contact
Email: oncology.clinical.trials@marshfieldresearch.org

Medford
Aspirus Medford Hospital
Contact: Site Public Contact
Email: Beth.Knetter@aspirus.org

Minocqua
Marshfield Clinic-Minocqua Center
Contact: Site Public Contact
Email: oncology.clinical.trials@marshfieldresearch.org

Neenah
ThedaCare Regional Medical Center - Neenah
Contact: Site Public Contact
Email: ResearchDept@thedacare.org

New London
ThedaCare Cancer Care - New London
Contact: Site Public Contact
Email: ResearchDept@thedacare.org

New Richmond
Cancer Center of Western Wisconsin
Contact: Site Public Contact
Email: mmcorc@healthpartners.com

Oconto Falls
Saint Vincent Hospital Cancer Center at Oconto Falls
Contact: Site Public Contact
Email: ewd_research_admin@hshs.org

Oshkosh
ThedaCare Cancer Care - Oshkosh
Contact: Site Public Contact
Email: ResearchDept@thedacare.org

Rice Lake
Marshfield Medical Center-Rice Lake
Contact: Site Public Contact
Email: oncology.clinical.trials@marshfieldresearch.org

Shawano
ThedaCare Cancer Care - Shawano
Contact: Site Public Contact
Email: ResearchDept@thedacare.org

Sheboygan
HSHS Saint Nicholas Hospital
Contact: Site Public Contact
Email: ewd_research_admin@hshs.org

Stevens Point
Ascension Saint Michael's Hospital
Contact: Site Public Contact
Email: ClinicalResearchAWI@ascension.org

Marshfield Medical Center-River Region at Stevens Point
Contact: Site Public Contact
Email: oncology.clinical.trials@marshfieldresearch.org

Sturgeon Bay
Green Bay Oncology - Sturgeon Bay
Contact: Brian Leslie Burnette

Saint Vincent Hospital Cancer Center at Sturgeon Bay
Contact: Site Public Contact
Email: ewd_research_admin@hshs.org

Waupaca
ThedaCare Cancer Care - Waupaca
Contact: Site Public Contact
Email: ResearchDept@thedacare.org

Wausau
Aspirus Regional Cancer Center
Contact: Site Public Contact

Marshfield Clinic-Wausau Center
Contact: Site Public Contact
Email: oncology.clinical.trials@marshfieldresearch.org

Weston
Marshfield Medical Center - Weston
Contact: Site Public Contact
Email: oncology.clinical.trials@marshfieldresearch.org

Wisconsin Rapids
Aspirus Cancer Care - Wisconsin Rapids
Contact: Site Public Contact

Marshfield Clinic - Wisconsin Rapids Center
Contact: Site Public Contact
Email: oncology.clinical.trials@marshfieldresearch.org

WV
Bridgeport
United Hospital Center
Contact: Site Public Contact
Email: cancertrialsinfo@hsc.wvu.edu

Martinsburg
WVUH-Berkely Medical Center
Contact: Site Public Contact
Email: cancertrialsinfo@hsc.wvu.edu

Morgantown
West Virginia University Healthcare
Contact: Site Public Contact
Email: cancertrialsinfo@hsc.wvu.edu

Parkersburg
Camden Clark Medical Center
Contact: Site Public Contact
Email: cancertrialsinfo@hsc.wvu.edu

WY
Cheyenne
Cheyenne Regional Medical Center-West
Contact: Site Public Contact
Email: ccrp@co-cancerresearch.org

Cody
Big Horn Basin Cancer Center
Contact: Site Public Contact
Email: ctsucontact@westat.com

Billings Clinic-Cody
Contact: Site Public Contact
Email: research@billingsclinic.org

Sheridan
Welch Cancer Center
Contact: Site Public Contact
Email: mccinfo@mtcancer.org

PRIMARY OBJECTIVE:
I. To compare the invasive disease-free survival (IDFS) in triple-negative breast cancer (TNBC) patients with residual basal-like disease after neoadjuvant chemotherapy who are randomized to post-preoperative platinum based chemotherapy with those who are randomized to capecitabine.

SECONDARY CLINICAL OBJECTIVES:
I. To evaluate overall survival (OS) and response-free survival (RFS) in the two arms in patients with TNBC with residual basal-like disease after neoadjuvant chemotherapy.
II. To characterize the side effects and tolerability of each platinum agent (cisplatin and carboplatin) as well as capecitabine in patients with TNBC with residual disease after neoadjuvant chemotherapy.
III. To identify the rate of basal-like gene expression using prediction analysis of microarray 50 (PAM50) analysis by digital messenger ribonucleic acid (mRNA) quantitation amongst drug-resistant residual TNBC after neoadjuvant chemotherapy.
IV. To compare the IDFS in TNBC patients with residual non-basal-like disease after neoadjuvant chemotherapy who are randomized to post-preoperative platinum based chemotherapy with those who are randomized to capecitabine (exploratory analysis).
V. To assess the difference in health-related quality of life (HRQL) between the platinum based and capecitabine chemotherapy arms.
VI. To describe the rate of neurotoxicity over time in the platinum arm, the rate of medication adherence in the capecitabine arm and the rates of amenorrhea in both arms (exploratory).

SECONDARY CORRELATIVE BIOMARKER OBJECTIVES:
I. To evaluate the association of genomic alterations identified via profiling of the surgical tumor specimen with RFS in patients with TNBC after neoadjuvant chemotherapy.
II. To explore whether any of the genomic alterations identified via profiling of the surgical tumor specimen can predict treatment benefit in patients with basal-like TNBC.
III. To determine the frequency of CTC positivity at baseline and after completion of study therapy in patients with TNBC with residual basal-like disease after neoadjuvant chemotherapy.
IV. To evaluate the associations between CTC levels at baseline, and after completion of chemotherapy, with RFS.
V. To evaluate the association between CTC change in status post-treatment (i.e. negative to negative, negative to positive, positive to negative, positive to positive) and RFS.
VI. To explore significance of CTC number/phenotype and ctDNA-detected mutations (mutational burden, specific mutations) in predicting RFS.

EXPLORATORY CORRELATIVE BIOMARKER OBJECTIVES:
I. To determine the frequency of plasma tumor cell-free DNA (cfDNA) positivity at baseline and after completion of study therapy in patients with TNBC with residual basal-like disease after neoadjuvant chemotherapy.
II. To evaluate the associations between plasma tumor cfDNA tumor-specific mutations (baseline and after therapy) with RFS.
III. To explore optimal biomarker combination for RFS prediction.

EXPLORATORY TOBACCO USE OBJECTIVES:
I. To determine the effects of tobacco, operationalized as combustible tobacco (1a), other forms of tobacco (1b), and environmental tobacco exposure (ETS) (1c) on provider-reported cancer-treatment toxicity (adverse events [both clinical and hematologic] and dose modifications).
II. To determine the effects of tobacco on patient-reported physical symptoms and psychological symptoms.
III. To examine quitting behaviors and behavioral counseling/support and cessation medication utilization.
IV. To explore the effect of tobacco use and exposure on treatment duration, relative dose intensity, and therapeutic benefit.

OUTLINE: Patients are randomized to 1 of 3 treatment arms.

ARM A (closed to accrual 05/16/2016): Patients undergo observation.

ARM B: Patients receive cisplatin intravenously (IV) or carboplatin IV on day 1. Treatment repeats every 3 weeks for 4 cycles in the absence of disease progression or unacceptable toxicity.

ARM C: Patients receive capecitabine orally (PO) twice daily (BID) on days 1-14. Treatment repeats every 3 weeks for up to 6 cycles in the absence of disease progression or unacceptable toxicity.

After completion of study treatment, patients are followed up every 3, 6, or 12 months for up to 10 years.

Interactive content above is from the official study record on the National Cancer Institute website, cancer.gov.


The ECOG-ACRIN Cancer Research Group designed and conducted this trial with funding from the National Cancer Institute through its National Clinical Trials Network.


EA1131 (Closed)
ECOG-ACRIN Cancer Research Group