The Advanced Practice Provider
Clinical Trials Research Manual

Created by representatives from across the cooperative research groups in the National Cancer Institute's (NCI) National Clinical Trials Network (NCTN), The Advanced Practice Provider Clinical Trials Research Manual is intended for advanced practice providers (APPs) who are new to clinical research or who wish to refresh their knowledge. The manual provides education and guidance for oncology APPs and their centers.

Topics covered in the manual include the types, phases, and endpoints of clinical trials; research team roles and responsibilities; the protocol development review process; regulatory affairs and data management; enrollment and informed consent processes; auditing and monitoring; the NCI Cancer Therapy Evaluation Program’s APP prescribing policy; and tips for discussing trials with potential participants.