The Advanced Practice Provider
Clinical Trials Research Manual
Created by representatives from across the cooperative research groups in the National Cancer Institute's (NCI) National Clinical Trials Network (NCTN), The Advanced Practice Provider Clinical Trials Research Manual is intended for advanced practice providers (APPs) who are new to clinical research or who wish to refresh their knowledge. The manual provides education and guidance for oncology APPs and their centers.
Topics covered in the manual include the types, phases, and endpoints of clinical trials; research team roles and responsibilities; the protocol development review process; regulatory affairs and data management; enrollment and informed consent processes; auditing and monitoring; the NCI Cancer Therapy Evaluation Program’s APP prescribing policy; and tips for discussing trials with potential participants.
A password is required to view the manual, which can be accessed in one of two ways:
- Cancer Trials Support Unit (CTSU) website (ctsu.cancer.gov): Resources > Researcher Resources > then under the heading “NCI Program and General LPO Resources > LPO Resources”
- ECOG-ACRIN Members’ website (ecog-acrin.org, member login, “Clinical and Administrative Resources”): User Group/Committee Resources > Advanced Practice Provider Committee (last item under APP Committee Member Information)
For additional questions/issues with access, please email bridget_obrien-fagan@rush.edu.
