Comis Symposium – Spring 2025
Robert L. Comis, MD Translational Science Symposium
Application of Technology in Studying Tumor Evolution and Targeting Different Types of Tumors
May 13, 2025
Tampa, FL
A highlight of the ECOG-ACRIN Group Meeting
This symposium is named for the ECOG-ACRIN Cancer Research Group’s late Group Co-Chair Robert L. Comis, MD (pictured at left). The potential of translational science to advance cancer diagnosis, prevention, and treatment was a guiding passion for Dr. Comis, and the symposium honors him in this way. Learn more about Dr. Comis here.
Agenda
Welcome
Peter J. O’Dwyer, MD and Mitchell D. Schnall, MD, PhD
ECOG-ACRIN Group Co-Chairs, University of Pennsylvania
Segment 1: Introduction and Overview of General Strategies for Circulating Markers
Tumor-Informed and Tumor-Uninformed ctDNA Approaches for Minimal Residual Disease Detection
Charu Aggarwal, MD, MPH
University of Pennsylvania/Abramson Cancer Center
Segment 2: Latest Technology
Applications of Circulating Marker Technology: Capabilities and Limitations
Gad Getz, PhD
Broad Institute of MIT and Harvard
Segment 3: Real World Examples
Dustin A. Deming, MD
University of Wisconsin/UW Carbone Cancer Center
Chair, ECOG-ACRIN Developmental Therapeutics Committee
ECOG-ACRIN Young Investigator of the Year for 2024
Segment 4: Trial Design
Practical Applications of ctDNA in Solid Tumors
Dejan Juric, MD
Harvard University/Mass General Cancer Center
Segment 5: Future Thinking
Design Considerations for a Trial in MRD-Positive Patients Following Initiation of Conventional Adjuvant Therapy
Keith T. Flaherty, MD
Harvard University/Mass General Cancer Center
Chair, ECOG-ACRIN Biomarker Steering Committee
Segment 6: Panel Discussion
Moderator
David A. Mankoff, MD, PhD
University of Pennsylvania
Panelists
Segment presenters named above, along with:
Barbara A. Burtness, MD
Yale University/Yale Cancer Center
Chair, ECOG-ACRIN Head and Neck Cancer Committee
Chair, ECOG-ACRIN Task Force on Career Advancement
Download the printed program to read speaker bios.