Numerous clinical trials are always open and enrolling patients in the ECOG-ACRIN Cancer Research Group, which focuses its research on adults 18 years of age and older who have or are at risk of developing cancer. This section of the website contains links to all materials that are publicly available to patients and researchers.
To access materials for a particular trial, click on the trial ID in the list below.
Cancer Type |
Trial ID and Target Patient Population |
Any Solid Tumor, Lymphoma, or Myeloma, or Cancer Type with No Standard Treatment Available | NCI-MATCH / EAY131 – Eligibility Based on Genetic Testing |
Brain | EAF151 – Glioblastoma, Recurrent |
Breast | EA1131 – Triple-Negative, Including Men |
EA1151 / TMIST – Screening Mammography | |
EA1181 / CompassHER2 pCR – HER2-Positive | |
EA1183 / FEATURE – Bone-dominant, Metastatic | |
EAI142 – Newly Diagnosed, Advanced | |
EAZ171 – Neuropathy in Black Women | |
6694 – Imaging of Women in the Alliance A011104 Trial | |
Cancer Care Delivery Research | EAQ171CD – Any Cancer, Stop-Smoking Counseling |
Cancer Control | EA9131 – Acute Promyelocytic Leukemia |
and Survivorship | E1Q11 / EROS – Any Cancer, Reproductive Health Planning |
EAQ172 – Any Cancer, Treatment of Lung Inflammation | |
EAQ191 / CARISMA – Blood Pressure Management | |
Gastrointestinal | EA2142 – Pancreas or Gastrointestinal Tract, Advanced |
EA2165 – Anal | |
EA2174 – Esophagus | |
EA2176 – Anal (Treatment-Naïve) | |
EA2182 / DECREASE – Anal, Squamous Cell | |
EA2183 – Esophagus and Gastric | |
EA2185 – Surveillance of Non-Cancerous Pancreas Cysts | |
EA2186 / GIANT – Pancreatic, Advanced (Aged 65+) | |
EA2187 – Bile Duct (Cholangiocarcinoma), Advanced | |
EA2197 / OPT-IN – Gallbladder | |
7151 – Detection of Colon Cancer (By Invitation Only) | |
Genitourinary | EA8134 / InPACT – Penis |
EA8143 / PROSPER RCC – Kidney | |
EA8153 / CHAARTED2 – Prostate, Hormone-Sensitive | |
EA8171 – Prostate (Imaging/Treatment Planning) | |
EA8183 / ERADICATE – Prostate (Post Prostatectomy) | |
EA8185 / INSPIRE – Bladder, Node Positive | |
EA8191 / INDICATE – Prostate (Recurrence) | |
Gynecologic | None at this time |
Head and Neck | EA3132 – p53-Mutated Squamous Cell, After Surgery |
EA3161 – Oropharyngeal Squamous Cell Carcinoma (Throat), HPV-Positive | |
EA3163 – Nose and Sinus, Squamous Cell | |
EA3191 – Recurrent Squamous Cell, High Risk Features | |
Leukemia | EA9131 – Acute Promyelocytic Leukemia |
EA9152 – Acute Lymphoblastic Leukemia (T-cell or B-cell) | |
EA9161 – Chronic Lymphocytic Leukemia | |
EA9171 – Myeloid Leukemia | |
EA9181 – Acute Lymphoblastic Leukemia (BCR-ABL-positive) | |
NHLBI-MDS / The National MDS Study – Observation of Myelodysplastic Syndromes | |
Lymphoma | EA4151 – Mantle Cell |
EA4181 – Mantle Cell | |
E4412 – Hodgkin | |
PrE0404 – Mantle Cell | |
PrE0405 – Mantle Cell | |
Melanoma | EA6134 / DREAMseq – Advanced, BRAFV600-Mutated |
EA6141 – Advanced | |
EA6174 / STAMP – Merkel Cell, After Surgery | |
EA6183 – Cutaneous or Unknown Primary | |
EA6191 / BAMM2 – Advanced, BRAF V600E/K | |
EA6192 / PET-Stop – Advanced | |
Myeloma | EAA173 / DETER-SMM – Smoldering Myeloma |
EAA181 / EQUATE – Multiple Myeloma (Newly Diagnosed) | |
Prevention | EAZ171 – Neuropathy in Black Women |
Thoracic (Lung Cancer) | EA5162 – Non-Small Cell, Advanced |
EA5163 / S1709 / INSIGNA – Non-Small Cell, Advanced | |
EA5181 – Non-Small Cell, Unresectable | |
EA5182 – Non-Small Cell, Advanced | |
EA5191 – Non-Squamous Non-Small Cell | |
E4512, an ALCHEMIST trial – Non-Small Cell, Early | |
Lung-MAP – Squamous Cell. Previously Treated | |
4703 / DECAMP-1 – Detection in Military Personnel | |
4704 / DECAMP-2 – Screening of Military Personnel | |
6697 – Imaging of Patients in the RTOG 1106 Trial |
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