EA6244

This clinical trial is exploring less intense treatment for older patients with early-stage melanoma, particularly those with thicker tumors. These patients typically undergo a wide local excision (WLE) surgery to remove the melanoma and a margin of healthy-looking tissue around all of its edges. Then, they have a second surgery, called a sentinel lymph node biopsy (SLNB), in which the lymph nodes where cancer cells could spread are located and removed as well. This study compares the standard approach of two surgeries (WLE followed by SLNB) versus one surgery (WLE alone) and close lymph node monitoring. The goal is to determine whether WLE alone is equally effective and enhances patients’ quality of life.