Group Statistician, ECOG-ACRIN Cancer Research Group
Constantine A. Gatsonis, PhD, is the Henry Ledyard Goddard University Professor of Biostatistics and Chair, Department of Biostatistics at Brown University, where he joined the faculty in 1995 as the founding Director of the Center for Statistical Sciences. Dr. Gatsonis is a leading authority on the design and analysis of clinical trials of diagnostic and screening modalities and has extensive involvement in methodologic research in medical technology assessment and health services research and comparative effectiveness research. He has served as Network Statistician of the American College of Radiology Imaging Network (ACRIN) since the founding of the network in 1999. ACRIN’s Digital Mammography Imaging Screening Trial and its arm of the National Lung Screening Trial occurred under his methodologic leadership. He was the lead statistician for the International Breast Magnetic Resonance Imaging Consortium, whose study published in 2004, and head of the Radiologic Diagnostic Oncology Group of the National Institutes of Health from 1988 to 1995.
Dr. Gatsonis has worked extensively on the development of statistical methods for the evaluation of diagnostic tests and biomarkers. He has published on methodology for receiver operating characteristic analysis, the assessment of the predictive value of tests, and the design of reader studies, as well as on broader issues in the evaluation and validation of diagnostic test and imaging biomarkers.
Dr. Gatsonis is the founding Editor-in-Chief of Health Services and Outcomes Research Methodology. He is also currently an associate editor of the Annals of Applied Statistics, Clinical Trials, and Academic Radiology, and is an editor of the Diagnostic Test Accuracy Reviews of the Cochrane Collaboration. He was a member of the Steering Group of the Standards for Reporting of Diagnostic Accuracy project, which published the first comprehensive checklist for reporting the results of diagnostic test evaluations, and co-convenor of the Screening and Diagnostic Tests Methods Working Group of the Cochrane Collaboration.
Dr. Gatsonis currently serves on the Research Development Committee of the Radiology Society of North America. He is Chair of the National Academy of Sciences (NAS) Committee on Applied and Theoretical Statistics and Co-Chair of the NAS Committee on Identifying the Needs of the Forensic Sciences Community. He has served on the Institute of Medicine (IOM) Immunization Safety Review Committee and the IOM Committee on Comparative Effectiveness Research Prioritization.
Dr. Gatsonis is a fellow of the American Statistical Association and the Association for Health Services Research.
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