Numerous clinical trials are always active (ie, open and enrolling patients) in the ECOG-ACRIN Cancer Research Group, which focuses its research on adults who have or are at risk of developing cancer. The buttons below depict the general research categories being investigated in ECOG-ACRIN clinical trials. To access information within a particular category, click on the relevant button. Upon clicking, the color of the button will change from grey to red, and a table will appear on screen. The table will display the study number, study description, lead investigator(s), accrual goal, and the date the trial was activated (began enrolling patients). Please read the ECOG-ACRIN Disclaimer in its entirety before accessing this information.
To inquire about a particular trial, send us an email using our contact form. Alternatively, send an email to the study chair; click on their hyperlinked name and a new email window will open. To view educational materials, click on the links provided in the Educational Materials column.
Melanoma Trials Currently Recruiting Participants
STUDY DESCRIPTION ECOG-ACRIN STUDY CHAIR
EA6134 A Randomized Phase III trial of Dabrafenib + Trametinib followed by Ipilimumab + Nivolumab at Progression vs. Ipilimumab + Nivolumab followed by Dabrafenib + Trametinib at Progression in Patients with Advanced BRAFV600 Mutant Melanoma
Michael B. Atkins, MD, Chair
(Sandra Lee, ScD)
EA6141 Randomized Phase II/III Study of Nivolumab plus Ipilimumab plus Sargramostim versus Nivolumab plus Ipilimumab in Patients with Unresectable Stage III or Stage IV Melanoma
***A pause to all new accrual to EA6141 is effective 06/23/2017 to conduct a planned interim analysis.***
F. Stephen Hodi, MD,
Ahmad A. Tarhini, MD, PhD, Co-Chair
(Sandra Lee, ScD)