Numerous clinical trials are always open and enrolling patients in the ECOG-ACRIN Cancer Research Group, which focuses its research on adults 18 years of age and older who have or are at risk of developing cancer. This section of the website contains all educational materials that are publicly available to patients and researchers.
To access educational materials for a particular trial, click on the trial ID in the list below. Materials for closed trials (no longer enrolling patients) can be found in the Archived Educational Materials section.
Cancer Type |
Trial ID and Target Patient Population |
| Any Solid Tumor, Lymphoma, or Myeloma, or Cancer Type with No Standard Treatment Available | NCI-MATCH / EAY131 – Eligibility Based on Genetic Testing |
| Brain | EAF151 – Recurrent Glioblastoma |
| Breast | EA1151 aka TMIST – Evaluating Two Current Mammography Methods for Breast Cancer Screening |
| EAI142 – Newly Diagnosed Metastatic Breast Cancer | |
| EA1131 – Triple-Negative (Including Men) | |
| EA1141 – Imaging Study for Women with Dense Breasts | |
| E2112 – Advanced, Hormone Receptor-Positive and Resistant to Aromatase Inhibitors (Including Men) | |
| ACRIN 6694 – Imaging Substudy for Women in the Alliance A011104 Trial | |
| A011401 aka BWEL – Evaluating the Role of Weight Loss in Overweight Women with Early Breast Cancer | |
| Gastrointestinal | EA2161 – Rapalog-Resistant Advanced Pancreatic Neuroendocrine Tumors |
| EA2133 – Advanced Anal Cancer- Inoperable, Locally Recurrent or Metastatic | |
| EA2142 – Advanced G3 Non-Small Cell Gastroenteropancreatic Neuroendocrine Carcinomas | |
| EA2131 – Advanced Pancreatic | |
| ACRIN 7151 – Detection of Colon Cancer (By Invitation Only) | |
| Genitourinary | EA8143 aka PROSPER RCC – Renal Cell Carcinoma |
| EA8134 aka InPACT – Penile Advanced Cancer | |
| EA8141 – Upper Urinary Tract | |
| E2810 – Advanced Renal Cell | |
| Head and Neck | E3311 – Locally Advanced HPV-Positive Throat |
| EA3132 – p53 Mutated, Surgically Resected Squamous Cell Carcinoma of the Head and Neck (SCCHN) | |
| Leukemia | EAI141 – Acute Myeloid |
| E1910 – Acute Lymphoblastic (ALL) | |
| E2906 – Acute Myeloid (AML) in Adults 60 Years Old or Older | |
| NHLBI-MDS aka The National MDS Study – Observation of Myelodysplastic Syndromes (MDS) | |
| Lymphoma | E4412 – Hodgkin |
| Melanoma | EA6134 – Advanced, BRAFV600 Mutant |
| EA6141 – Advanced | |
| E3612 – Advanced, Not Removable by Surgery | |
| Myeloma | E1A11 aka ENDURANCE – Symptomatic |
| E3A06 – Asymptomatic High-Risk Smoldering | |
| Patient-Centered Outcomes | E1Q11 aka EROS – Reproductive Health Planning |
| and Survivorship | E1Z11 aka AIMSS – Genetic Predictors |
| EAQ152 aka COMET – Education in Tumor Profiling | |
| Thoracic | E4512, an ALCHEMIST treatment trial – Early, Non-Squamous Non-small Cell, Removed by Surgery |
| EA5142, an ALCHEMIST treatment trial – Non-small Cell, Post Surgery and Adjuvant Chemotherapy | |
| ACRIN 4703 aka DECAMP-1 – Detection of Early Lung Cancer in Military Personnel | |
| ACRIN 4704 aka DECAMP-2 – Screening of Military Personnel with Early Stage Lung Cancer or at High Risk of Developing Lung Cancer | |
| ACRIN 6697 – Imaging Substudy for Patients in the RTOG 1106 Trial | |
| Lung-MAP – Squamous Cell |
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